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    FormatThesis (8)SubjectBacteriophages -- genetics (2)Collagen Type I -- metabolism (2)Mice, Mutant Strains (2)Osteogenesis Imperfecta -- genetics (2)Peptide Library (2)... View MoreDate Issued2010 (1)2009 (1)2006 (3)2005 (3)Author/ContributorDeutscher, Susan L. (3)Phillips, Charlotte L. (2)Bates, Maura K. (1)Brodeur, Amanda C., 1978- (1)Hannink, Mark, 1958- (1)... View MoreAdvisorDeutscher, Susan L. (3)Phillips, Charlotte L. (2)Hannink, Mark, 1958- (1)Martin, Mark E. (1)Sun, Grace Y. (1)Thesis Department
    Biochemistry (Medicine) (MU) (8)
    Language (ISO)English (8)

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    Characterization of peptides and phage that bind galectin-3 selected from bacteriophage display libraries: a study of the role of galectin-3 in metastasis-associated cancer cell adhesion 

    Zou, Jun, 1970- (University of Missouri--Columbia, 2005)
    Intravascular cancer cell adhesion plays a significant role in the metastatic process. Studies indicate that galectin-3, a member of the galectin family of soluble animal lectins, is involved in carbohydrate-mediated ...

    Crystal structure of the kelch domain of human keap1 

    Li, Xuchu, 1976- (University of Missouri--Columbia, 2005)
    [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Nrf2-Keap1 signal transduction pathway senses oxidative stress and protects eukaryotic cells against oxidative damage and cancer. The transcription ...

    GABP regulation of the murine GABPa/ATPsynthase coupling factor six and human glutathione reductase promoters 

    Patton, John David, 1976- (University of Missouri--Columbia, 2005)
    GABPa is expressed from a bi-directional promoter expressing ATP synthase coupling factor six (CF6) in the opposite direction. This bi-directional promoter is regulated by GABP, indicating an autoregulation of GABPa. GABP ...

    Glomerular deposition of homotrimeric type I collagen in the COL1A2 deficient mouse 

    Brodeur, Amanda C., 1978- (University of Missouri--Columbia, 2006)
    Type I collagen is the most abundant structural protein in the body. Type I collagen generally exists as a heterotrimeric protein; however, a homotrimeric isotype of type I collagen has been identified. Our lab currently ...

    Role of Proa(2)I collagen chains and collagen crosslinking in thoracic aortic biochemical integrity during aging using the OIM mouse model 

    Pfeiffer, Brent J., 1975- (University of Missouri--Columbia, 2006)
    The extracellular matrix (ECM) is an important constituent for a variety of tissues including vascular tissue in which the ECM maintains aortic wall integrity. An important component of vascular tissue ECM is type I collagen. ...

    Secretory phospholipase A2-IIA in Alzheimer's disease and inflammatory responses in astrocytes 

    Jensen, Michael D., 1979- (University of Missouri--Columbia, 2009)
    Alzheimer's disease (AD) is a progressive, fatal neurodegenerative disease marked with dementia. Secretory phospholipase A2-IIA (sPLA2-IIA) is an inflammatory protein known to have a role in the pathogenesis of multiple ...

    The use of FD-filamentous bacteriophage for the in vivo imaging of cancer 

    Newton, Jessica R. (University of Missouri--Columbia, 2006)
    Improved diagnosis of cancer through targeted imaging of neoplasms is needed for early detection and treatment of cancer. We propose that the physical characteristics of filamentous bacteriophage (phage) are well suited ...

    Phage display peptides for breast cancer targeting 

    Bates, Maura K. (University of Missouri--Columbia, 2010)
    Cancer cell surfaces differ from healthy cell surfaces allowing the detection of cancer targets on the cell. Use of these targets combined with radiolabeled targeting vehicles results in sensitive imaging agents, with ...

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