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Discovery of Peptide and Aptamer Ligands for Targeted Drug Delivery to Hepatic Stellate Cells
(University of Missouri--Kansas City, 2016)
The objective of this dissertation is to present two approaches to identify Hepatic Stellate Cells (HSCs) targeting ligands using phage-display library biopanning and systematic evolution of ligands by exponential ...
Identification of Cell Types that Define Embryonic Submandibular and Parotid Salivary Glands Using Single Cell RNA Sequencing
(University of Missouri -- Kansas City, 2019)
Branching organs including the kidney, mammary, and salivary glands arise as epithelial buds that are morphologically very similar. However, the mesenchyme is known to guide epithelial morphogenesis and to help govern ...
Evaluating the Ergonomics of Healthcare Providers using Kinematic Motion Analysis, Electromyography, and Musculoskeletal Modeling
(University of Missouri -- Kansas City, 2018)
Work-related musculoskeletal disorders (MSDs) in healthcare providers have been heavily reported, and are a major cause of occupational discomfort, disability, and occupational absence. Current evaluation methodology of ...