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Interferon regulatory factor 1 (IRF-1) directs IL-4/IL-13 induced death of neonatal Th1 cells
(University of Missouri--Columbia, 2017)
Newborns typically have immune responses that are allergic, due to a predominance of Th2 cells, and lack the ability to respond to vaccines as well as display poor protection against microbes, due to a lack of Th1 cells. ...