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The Middle Region is Required for Phosphorylation Regulation of Ceramide Transfer Protein
(2013)
The trafficking of ceramide from endoplasmic reticulum (ER), where it is synthesized, to the Golgi for sphingomyelin synthesis is mediated by the ceramide transfer protein (CERT) in a nonvesicular fashion. CERT is a cytosolic ...
The canonical Wnt signaling pathway affects regeneration of mechanosensory hair cells in Danio Rerio
(2020)
In vertebrates, mechanosensory hair cells are located in the inner ear and mediate hearing. When damage to these specialized cells occur, it leads to irreversible hearing loss. Not only do aquatic vertebrates have inner ...
Expression Pattern of Drug-Resistance Genes in Matched Clinical Isolates of Candida albicans at Variable Fluconazole Exposure Times
(2016)
Candida albicans is an opportunistic fungus that exists naturally in the vaginal, urinary, and gastrointestinal tracts of humans. Typically, this yeast remains balanced with the body’s other natural microbial flora and the ...
A single molecule study on the structural basis of ion selective permeation in voltage-gated sodium channels
(2021)
High resolution studies of voltage-gated sodium channels (VGSCs) can not reveal the dynamic nature of the channel structures, especially in lipid environments, which are vital for rational drug design. The bacterial NavAb ...