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Characterization of the relationship between radiographic grading and biomarkers in patients with knee osteoarthritis
(University of Missouri--Columbia, 2020)
"Osteoarthritis (OA) is a whole-joint degenerative disease, affecting more than 25% of the adult population. Currently, OA is most commonly diagnosed based on radiographic documentation. However, radiographic grading is ...
Intervertebral discs : metabolic responses to load, injury, and pro-inflammatory stimulation
(University of Missouri--Columbia, 2020)
Introduction: Intervertebral disc (IVD) degeneration is a significant cause of back pain and disability. Factors such as trauma and magnitude and frequency of loading are associated with IVD degeneration. However, the ...
Brassicales to Brassica : integrating phylogenomics and population genomics
(University of Missouri--Columbia, 2020)
The Brassicales are an economically important order of flowering plants. Many crop species such as kale, broccoli, cabbage, cauliflower, canola oil, capers, and papaya, as well as the model plant organism, Arabidopsis ...
The blue light responses and lifetime fitness of a hyper-phototropic mutant in Arabidopsis thaliana and Zea mays
(University of Missouri--Columbia, 2020)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Optimal plant growth and development hinges on the plant's ability to absorb sunlight. Because plants are sessile, they have evolved a variety of ...
Dissecting the genetic basis of learning, memory, and thermal tolerance in a multi-parental population of fruit flies
(University of Missouri--Columbia, 2021)
Learning, memory, and thermal tolerance are complex traits that are fundamental survival skills in many species. For example, small poikilotherms " like Drosophila melanogaster, have evolved physiological mechanisms to ...
Weed versus wildflower : mating system ecology in a taraxacum native-exotic contact zone
(University of Missouri--Columbia, 2020)
Closely related plant species often exhibit differences in ploidy level, mode of reproduction, and traits related to reproduction. Differences in ploidy levels are often associated with mating system differentiation, ...
Coupling, membrane conductance, and ion channel mRNA profiles in the establishment and maintenance of network activity in the crustacean cardiac ganglion
(University of Missouri--Columbia, 2021)
Neural networks produce critical rhythmic behaviors throughout an animal's lifespan, despite growth, differing environments, and changes in physiological state. This requires networks which balance stability in their ...
Uncovering the genetic architecture and metabolic basis of amino acid composition in maize kernels using multi-omics integration
(University of Missouri--Columbia, 2020)
Seeds are a major source of protein in human and livestock diets. Cereal grains are some of the most consumed seeds by both humans and livestock worldwide, with maize, wheat, and rice alone accounting for ~70% of the total ...
The genetic and physiological basis of total energy budget in different nutritional environments
(University of Missouri--Columbia, 2020)
Organisms need to adapt to dynamic environments over time. An organism consumes and stores a finite amount of resources that are used for all daily tasks. In order to survive and thrive, they must allocate these finite ...
Low-level laser therapy for the treatment of osteoarthritis in the dog
(University of Missouri--Columbia, 2020)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] In veterinary medicine there is increasing interest in the use of low-level laser therapy (LLLT) for the treatment of pain in dogs with OA. ...
Genetic and hormonal regulation of meristem initiation and maintenance pathways during maize vegetative and reproductive development
(University of Missouri--Columbia, 2021)
Plant development is driven by pools of undifferentiated stem cells called meristems. Meristems have two functions, to divide producing cells that will replenish the stem-cell niche, and cells that will differentiate into ...
Interactions between neuroanatomy, cognition, and ecology in Anolis lizards
(University of Missouri--Columbia, 2021)
The interactions between an organism and its environment are mediated by cognition, the substrates of which are in the brain. Cognition is ubiquitous across vertebrates, yet we still know very little about the factors ...
Role of neuronal positioning in jaw motor circuit function in zebrafish
(University of Missouri--Columbia, 2021)
Development of the vertebrate nervous system involves substantial cell migration, where immature neurons move to specific locations to generate functional circuits. Precise neuronal migration and positioning are essential ...
Characterizing a model of early human placenta
(University of Missouri--Columbia, 2020)
In the few weeks following fertilization of a human ovum, there is little known about the events of early human development. What we do know we've learned from a few collections of fixed sections of implantation sites ...
Methodological approaches for sound training in underepresented learners: a case study with american toads (Anaxyrus americanus)
(University of Missouri--Columbia, 2021)
efforts to better understand the minds of animals have been flourishing, with methodological breakthroughs and a remarkable increase in the number of publications dealing with a wide variety of non-model species. The growing ...
Uncovering the genetic basis of seed amino acid composition in arabidopsis using a multi-omics integrative approach
(University of Missouri--Columbia, 2021)
Seeds are a vital source of protein in the diet of humans and livestock. However, protein composition in the seed is low, comprising about 10 percent of the total composition in the seed. Additionally, protein quality in ...
Ecological genomics of divergence, admixture, and fitness in the smallmouth bass (Micropterus dolomieu)
(University of Missouri--Columbia, 2021)
The Smallmouth Bass (Micropterus dolomieu) is one of the most highly targeted sport fishes in the world. Anglers vie for the opportunity to catch Smallmouth Bass recreationally and competitively, spending billions of dollars ...
The power of synteny : deep evolutionary insights from comparative genomics
(University of Missouri--Columbia, 2021)
Synteny, or the order of genes in a given genome, is an emergent property of individuals and species that has only, with the implementation of next gen-sequencing, become available for evolutionary consideration. In this ...
Conservation genetics of conflict in the Asian elephant, Elephas maximus
(University of Missouri--Columbia, 2021)
The Asian elephant (Elephas maximus) is an endangered species whose distribution spans 13 countries in south, southeast, and insular Asia. The primary threats to the survival of this species include direct conflict, primarily ...