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Gene therapy in spinal muscular atrophy : RNA-based strategies to modulate the pre-mRNA splicing of survival motor neuron
(University of Missouri--Columbia, 2008)
Gene expression is the required process in eukaryotes in which DNA is transcribed into pre-mRNA, spliced to produce "mature" mRNA and translated into proteins. Inaccuracies in splicing events are receiving more attention ...
Mechanisms of clostridial toxin binding and translocation
(University of Missouri--Columbia, 2018)
The bacterial genus Clostridium consists of over 150 species of anaerobic, fermentative, spore-forming bacilli. Clostridial species produce up to 20% of all known bacterial exotoxins, which serve as important virulence ...