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Prehospital intravenous access and fluid resuscitation in severe sepsis: an observational cohort study
(2014-09-27)
Abstract
Introduction
Prompt treatment of severe sepsis in the Emergency Department reduces deaths, but the role of prehospital ...
Activated protein C resistance in Behcet's disease
(2013-09-02)
Abstract
Behcet’s disease is a chronic multi-system disorder of unknown etiology with protean manifestations. Venous thromboembolism is more common than arterial thrombosis, with deep vein thrombosis being the ...
Separating signal from noise: the challenge of identifying useful biomarkers in sepsis
(2014-03-17)
Abstract
Sepsis diagnosis remains based largely on clinical presentation despite significant advances in the understanding of underlying pathophysiology and host-pathogen interactions. The systematic review article by ...
Factors associated with sterilization use among women leaving a U.S. jail: a mixed methods study
(2014-07-31)
Abstract
Background
Despite the high rates of reported sterilization use among women who have spent time in correctional facilities, little is known about the context in which women in this ...
Combined meta-analysis of systemic effects of allogeneic stem cell transplantation and systemic sclerosis
(2014-03-22)
Abstract
Background
Chronic graft-versus-host disease (cGVHD) is a major factor of morbidity and mortality for allogeneic stem cell transplantation (aSCT). The skin and internal organ involvement ...
Antioxidant-mediated up-regulation of OGG1 via NRF2 induction is associated with inhibition of oxidative DNA damage in estrogen-induced breast cancer
(2013-05-22)
Abstract
Background
Estrogen metabolism-mediated oxidative stress is suggested to play an important role in estrogen-induced breast carcinogenesis. We have earlier demonstrated that antioxidants, ...
An embedded multichannel telemetry unit for bone strain monitoring
(2013-10-17)
Abstract
An embedded telemetry unit for bone strain monitoring is presented. The telemetry unit is designed using commercially available components to lower design time and manufacturing ...
Human immunodeficiency virus type 1 viral protein R (Vpr) induces CCL5 expression in astrocytes via PI3K and MAPK signaling pathways
(2013-11-13)
Abstract
Background
Neurocognitive impairments remain prevalent in HIV-1 infected individuals despite current antiretroviral therapies. It is increasingly becoming evident that astrocytes ...
Computational analysis and predictive modeling of polymorph descriptors
(2013-02-04)
Abstract
Background
A computation approach based on integrating high throughput binding affinity comparison and binding descriptor classifications was utilized to establish the ...
Recurrent acute pancreatitis and massive hemorrhagic ascites secondary to a duodenal duplication in a child: a case report
(2013-03-14)
Abstract
Introduction
Duodenal duplication is a rare congenital malformation and has been reported as a rare cause of recurrent acute pancreatitis. Hemorrhagic ascites has been reported in only ...
Visual gene-network analysis reveals the cancer gene co-expression in human endometrial cancer
(2014-04-23)
Abstract
Background
Endometrial cancers (ECs) are the most common form of gynecologic malignancy. Recent studies have reported that ECs reveal distinct markers for molecular pathogenesis, ...
Cardiac thromboxane A2 receptor activation does not directly induce cardiomyocyte hypertrophy but does cause cell death that is prevented with gentamicin and 2-APB
(2014-12-17)
Abstract
Background
We have previously shown that the thromboxane (TXA2) receptor agonist, U46619, can directly induce ventricular arrhythmias that were associated with increases in intracellular ...
Evaluation of a new fluorescence quantitative PCR test for diagnosing Helicobacter pylori infection in children
(2013-01-14)
Abstract
Background
Numerous diagnostic tests are available to detect Helicobactor pylori (H. pylori). There has been no single test available to detect H. pylori infection reliably. We evaluated ...
Regional pulse wave velocities and their cardiovascular risk factors among healthy middle-aged men: a cross-sectional population-based study
(2014-01-13)
Abstract
Background
Both carotid-femoral (cf) pulse wave velocity (PWV) and brachial-ankle (ba) PWV employ arterial sites that are not consistent with the path of blood flow. Few previous ...
RNA-seq analysis of synovial fibroblasts brings new insights into rheumatoid arthritis
(2012-12-21)
Abstract
Background
Rheumatoid arthritis (RA) is a chronic autoimmune-disease of unknown origin that primarily affects the joints and ultimately leads to their destruction. Growing evidence ...
ART adherence changes among patients in community substance use treatment: a preliminary analysis from MACH14
(2012-10-11)
Abstract
Background
Opiate substitution treatment has been associated with better adherence to lifesaving antiretroviral medications, but the impact of other substance abuse treatment on ...
The neuroprotective properties of palmitoylethanolamine against oxidative stress in a neuronal cell line
(2009-12-10)
Abstract
Background
N-acylethanolamines (NAEs) are lipids upregulated in response to cell and tissue injury and are involved ...
A new permutation strategy of pathway-based approach for genome-wide association study
(2009-12-18)
Abstract
Background
Recently introduced pathway-based approach is promising and advantageous to improve the efficiency of ...
NQAR: Network Quality Aware Routing in Error-Prone Wireless Sensor Networks
(2009-11-10)
We propose a network quality aware routing (NQAR) mechanism to provide an enabling method of the delay-sensitive data delivery over error-prone wireless sensor networks. Unlike the existing routing methods that select ...
Hepatocellular proliferation in response to agonists of peroxisome proliferator-activated receptor alpha:a role for kupffer cells?
(2006-11-27)
Abstract
Background
It has been proposed that PPARα agonists stimulate Kupffer cells in rodents which in turn, release ...