Search
Now showing items 1-20 of 115
Suppression of nitric oxide induction and pro-inflammatory cytokines by novel proteasome inhibitors in various experimental models
(2011-10-12)
Abstract
Background
Inflammation has been implicated in a variety of diseases associated with ageing, including cancer, cardiovascular, and neurologic diseases. We have recently established that the proteasome ...
Inhibition of nitric oxide in LPS-stimulated macrophages of young and senescent mice by delta-tocotrienol and quercetin.
(2011-12-20)
Abstract
Background
Changes in immune function believed to contribute to a variety of age-related diseases have been associated with increased production of nitric oxide (NO). We have recently reported that ...
Encapsulation of docetaxel in oily core polyester nanocapsule intended for breast cancer therapy
(2011-12-14)
Abstract
This study is designed to test the hypothesis that docetaxel [Doc] containing oily core nanocapsules [NCs] could be successfully prepared with a high percentage encapsulation efficiency [EE%] and high drug loading. ...
Association of 25-hydroxyvitamin D deficiency with NT-pro BNP levels in patients with acute myocardial infarction: a cross-sectional analysis
(2011-12-15)
Abstract
Background
Nutritional vitamin D deficiency is an emerging risk factor for acute myocardial infarction (AMI) and heart failure. The association of 25-hydroxyvitamin D levels with N-terminal pro B-type natriuretic ...
The neuroprotective properties of palmitoylethanolamine against oxidative stress in a neuronal cell line
(2009-12-10)
Abstract
Background
N-acylethanolamines (NAEs) are lipids upregulated in response to cell and tissue injury and are involved ...
A new permutation strategy of pathway-based approach for genome-wide association study
(2009-12-18)
Abstract
Background
Recently introduced pathway-based approach is promising and advantageous to improve the efficiency of ...
NQAR: Network Quality Aware Routing in Error-Prone Wireless Sensor Networks
(2009-11-10)
We propose a network quality aware routing (NQAR) mechanism to provide an enabling method of the delay-sensitive data delivery over error-prone wireless sensor networks. Unlike the existing routing methods that select ...
Hepatocellular proliferation in response to agonists of peroxisome proliferator-activated receptor alpha:a role for kupffer cells?
(2006-11-27)
Abstract
Background
It has been proposed that PPARα agonists stimulate Kupffer cells in rodents which in turn, release ...
Hepatocellular proliferation in response to agonists of peroxisome proliferator-activated receptor alpha:a role for kupffer cells?
(2006-11-27)
Abstract
Background
It has been proposed that PPARα agonists stimulate Kupffer cells in rodents which in turn, release ...
Giant atypical carcinoid of the liver with vascular metastases and local sinusoidal invasion: a case report
(2007-07-12)
Abstract
We present the case of a 46 year old woman with a giant, 23-centimeter, atypical carcinoid of the liver. A primary site for this neoplasm could not be identified despite multiple radiographic ...
The validity of self-rated health as a measure of health status among young military personnel: evidence from a cross-sectional survey
(2006-08-29)
Abstract
Background
Single item questions about self ratings of overall health status are widely used in both military and ...
Tandem repeat regions within the Burkholderia pseudomallei genome and their application for high resolution genotyping
(2007-03-30)
Abstract
Background
The facultative, intracellular bacterium Burkholderia pseudomallei is the causative agent of melioidosis, a ...
FunnyBase: a systems level functional annotation of FundulusESTs for the analysis of gene expression
(2004-12-20)
Abstract
Background
While studies of non-model organisms are critical for many research areas, such as evolution, development, and ...
An informatics search for the low-molecular weight chromium-binding peptide
(2004-12-16)
Abstract
Background
The amino acid composition of a low molecular weight chromium binding peptide (LMWCr), isolated from ...
Associations between the built environment and physical activity in public housing residents
(2007-11-12)
Abstract
Background
Environmental factors may influence the particularly low rates of physical activity in African American and low-income adults. This cross-sectional study investigated ...
Diabetes (db/db) mutation-induced endometrial epithelial lipoapoptosis: Ultrastructural and cytochemical analysis of reproductive tract atrophy
(2005-04-27)
Abstract
Background
The diabetes (db/db) mutation in C57BL/KsJ mice promotes a progressive cytolipidemia within the endometrial ...
Glucocorticoid-like effects of antihepatocarcinogen Rotenone are mediated viaenhanced serum corticosterone levels: Molecular Fitting and Receptor Activation Studies
(2003-02-14)
Abstract
Background
Recent studies suggest that rotenone alters cell signal transduction pathways in a manner similar to ...
Hepatocarcinogenic potential of the glucocorticoid antagonist RU486 in B6C3F1 mice: effect on apoptosis, expression of oncogenes and the tumor suppressor gene p53
(2003-01-03)
Abstract
Background
Glucocorticoids inhibit hepatocellular proliferation and modulate the expression of oncogenes and tumor ...
CPP-ZFN: A potential DNA-targeting anti-malarial drug
(2010-09-16)
Abstract
Background
Multidrug-resistant Plasmodium is of major concern today. Effective vaccines or successful applications of RNAi-based strategies for the treatment of malaria are currently unavailable. An unexplored ...
Increased Mortality among Survivors of Myocardial Infarction with Kidney Dysfunction: the Contribution of Gaps in the use of Guideline-Based Therapies
(2009-07-08)
Abstract
Background
We assessed the degree to which differences in guideline-based medical therapy for acute myocardial ...