Osteogenesis imperfecta (OI), a heritable connective tissue disorder generally due to type I collagen defects, is characterized by small stature, reduced bone mineral density, and frequent fractures. Bone is inherently ...

OBJECTIVE: To investigate the incidence of auditory neuropathy, abnormal auditory brainstem response (ABR) with normal otoacoustic emissions, in newborn patients with craniosynostosis as compared to published standards. ...

Pinnacle Technology has developed successful university collaborations to bring new preclinical research systems to the marketplace. Primary funding for these collaborations has been through the NIH Small Business Innovation ...

A smart cardiovascular stent to be used as a single set of theranostics (therapeutics and diagnostics) is developed. The stent is aimed at delivering nitric oxide as a therapeutic agent and monitoring stent-induced restenosis. ...

The Transgenic and Gene-Targeting Facility at the University of Kansas Medical Center is located in the newly constructed Kansas Life Sciences Innovation Center on the KUMC campus. The mission of the Transgenic Facility ...

The preclinical development of a prodrug-based site-specific delivery strategy that allows for targeting a potent small-molecule neuroprotectant into the eye, and with preference to the retina, after topical administration ...

Cofactor Genomics is based in St. Louis, MO and provides sequencing and analysis services to academic and industry clients. We are a small company committed to changing the service sequencing paradigm by offering our ...

Mohs skin cancer surgery is also known as microscopically-controlled surgery because at each stage in the Mohs procedure, a new layer of tissue is obtained surgically and frozen sections made, allowing a microscopic reading ...

Background: Several million dogs are euthanized in animal shelters annually after multiple relinquishment reasons (Scarlett, 2002; Salman, 1998; New, 2000 & Kass, 2001). Gains in pet adoptions are happening via shelter ...

It has been hypothesized that osteocytes are stimulated by local strain distribution within the bone subjected to mechanical loadings. This collaborative research project between bone biologists and mechanical engineers ...

A high-accuracy, sensor system has been developed that provides near-instantaneous detection of biomarker proteins as indicators of ovarian serous papillary carcinoma. Based upon photonic guided-mode resonance technology, ...

Many microbes are capable of changing phenotypes more frequently than due to basal mutation rates alone, and this ability is coupled to pathogenesis. The human pathogenic yeast Cryptococcus neoformans is found in the ...

Introduction: Fat embolism, a subclinical event, occurs in many clinical settings, such as long bones fractures, liposuction and during cardiopulmonary bypass. Some cases, especially with trauma, result in fat embolism ...

Over 85% of cancer patients nationwide receive care in the community setting (NCI, 2007). In 2008, the Midwest Cancer Alliance (MCA) launched with a vision of marshaling the exceptional cancer resources of the region to ...

Introduction: National health organizations usually offer a limited variety of publication resources to the regional organizations that they serve. These resources may not always reflect the needs of the populations served ...

INTRODUCTION: Nanoparticles of many types have been created for industrial and medical applications. Among these nanoparticles, single-walled carbon nanotubes (SWCNT) are of high interest for their physicochemical properties ...

Organic Anion Transporting Polypeptides (OATPs) comprise a superfamily of sodium-independent membrane transporters which are involved in transporting numerous endogenous and exogenous substances. OATPs are expressed in ...

Skin Scan digital dermoscopy skin cancer detection software, developed by Rolla's S&A in collaboration with Missouri S&T, can now detect critical features of early melanoma. There is also a need for diagnostic help for ...

The development of safe and effective vaccines and adjuvants remains an important global public health goal. The Antigen Display on Bacillus Endospore (ADOBE) system, developed at the University of Missouri's College of ...

Successful businesses move new products through the development pipeline swiftly and efficiently. An integral part of this process is the research design and execution. The field of statistics can provide knowledge and ...