Search
Now showing items 1-4 of 4
Regulation of ceramide synthase 1 in cellular stress response
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Ceramides are intimately involved in a wide range of cellular processes. In mammals, de novo ceramide synthesis is catalyzed by the 6 ceramide synthase ...
Sphingolipid metabolic enzymes modulate anticancer drug resistance
(University of Missouri--Columbia, 2006)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] One of the most challenging aspects of cancer therapy today is the problem of drug resistance. The aim of our research is to understand the molecular ...
Drug resistance in D. discoideum: isolation of 4-nitroquinoline 1-oxide resistant mutants
(University of Missouri--Columbia, 2005)
The drug 4-nitroquinoline 1-oxide (4NQO) displays both carcinogenic and antitumor effects, a well known characteristic of many chemotherapeutic drugs. In addition 4NQO shares a similar operating mechanism with the commonly ...
Curcumin regulates transcription in Dictyostelium discoideum
(University of Missouri--Columbia, 2016)
Botanicals are widely used as dietary supplements and for the prevention and treatment of a myriad of diseases ranging from the common cold to depression. One in four Americans uses a botanical as part of their primary ...