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Development of a human immunodeficiency virus (HIV-1) biosensor utilizing liquid core waveguides
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Millions of individuals are diagnosed each year with Human Immunodeficiency Virus Type 1. Each day more individuals are receiving antiretroviral ...
Optical glucose nanobiosensor encapsulated in erythrocytes
(University of Missouri--Columbia, 2007)
An implantable glucose biosensor encapsulated in erythrocytes, Red Blood Cells (RBC), will become a method for continuously measuring blood glucose concentration in diabetics. In 2005, the American Diabetes Association ...
Development of a FRET biosensor to detect the pathogen mycoplasma capricolum
(University of Missouri--Columbia, 2005)
Mycoplasmas are a species of bacteria that invade any type of cell and are adaptable to changing environments. We are developing an optical biosensor based on Fluorescence Resonance Energy Transfer (FRET) for detection of ...
Development of a fluorescence resonance energy transfer optical nanoscale biosensor based on a liquid-core waveguide platform
(University of Missouri--Columbia, 2007)
In order to produce a more versatile, adaptable, and effective method for detection of biological analytes, a self-contained and robust fluorescent optical biosensor architecture utilizing fluorescence resonance energy ...
Development of a capillary based helicobacter hepaticus biosensor
(University of Missouri--Columbia, 2006)
Helicobacter hepaticus causes hepatitis in mice. Infections with H. hepaticus can invalidate animal research studies and early detection helps curtail the spread of infection. The objective of this study was to develop a ...
A novel PCR based DNA microanalyzer system for detection of viral genome
(University of Missouri--Columbia, 2006)
A micro-fluidic assay to quickly analyze microscopic samples of DNA is being developed for field applications. It consists of a micro-PCR chamber, micropumps, and micro-heaters. Additional components of the device include ...
Development of novel bionanocomposite scaffolds
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The development of three novel bionanocomposite scaffolds is presented in this dissertation. These scaffold materials are comprised of amine-functionalized ...
Development of electrospun synthetic bioabsorbable fibers for a novel bionanocomposite hernia repair material
(University of Missouri--Columbia, 2008)
In order to create a more durable and biocompatible hernia repair mesh, a novel bionanocomposite material based on the crosslinking of bioabsorbable polymer fibers to decellularized porcine diaphragm tissue is proposed. ...
Investigative study of long-term packaging effects and donor characteristics on acellular dermis scaffolds
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Acellular tissue sources have become progressively popular for a variety of tissue engineering and medical applications, such as soft tissue augmentation, ...
Development of a post-traumatic osteoarthritis model to evaluate the effects of impact velocity and maximum strain on articular cartilage cell viability, matrix biomarkers, and material properties
(University of Missouri--Columbia, 2009)
Post-traumatic osteoarthritis (PTOA) is a very painful and debilitating disease that is associated with mechanical injury to articular cartilage, yet the severity of trauma required to induce it is unknown. The objective ...