Now showing items 1-5 of 5
The role of the P2Y₂ nucleotide receptor in inflammation: the mechanisms of P2Y₂ receptor-mediated activation of G proteins
(University of Missouri--Columbia, 2007)
The extracellular ATP/UTP receptor, i.e., the P2Y₂ receptor (P2Y₂R), mediates pro-inflammatory responses in the vasculature, including the endothelium-dependent infiltration of monocytes and their transmigration into sites ...
Mechanisms of salivary gland cell proliferation in vitro by P2Y2R activation
(University of Missouri--Columbia, 2012)
Sjögren's syndrome (SS) and the side-effects of γ-radiation therapies for head and neck cancers cause salivary gland dysfunction. Salivary gland regeneration has been considered to be a very promising approach for restoring ...
The role of the P2Y2 nucleotide receptor in salivary gland regeneration
([University of Missouri--Columbia], 2014)
Salivary gland dysfunction affects millions of Americans whose quality of life is severely impacted by dry mouth, oral bacterial infections, poor nutrition, and other disorders that are associated with decreased saliva ...
Role of the P2Y2 nucleotide receptor in inflammation and inflammatory diseases
(University of Missouri--Columbia, 2015)
Nucleotides are released from cells in response to tissue damage and activate P2X and P2Y receptors on the cell surface to regulate inflammation, a critical process for wound repair. During inflammation, leukocytes are ...
Neuroprotective roles of the P2Y[subscript 2] nucleotide receptor
(University of Missouri--Columbia, 2014)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Alzheimer's disease (AD) is the most prevalent neurodegenerative disease. AD is an important disease to study because of the high cost of care for ...