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General genetic recombination in bacteriophage T4 : DNA exchange, DNA- protein-protein interactions
(University of Missouri, Agricultural Experiment Station, 1979)
We will discuss current models of genetic recombination emphasizing their general aspects and the specific points which have been demonstrated in phage T4. Recombination in this phage occurs preferentially (although not ...
Neurospora as an object for cytogenetic research : chromosome rearrangements, crossing over, duplications, meiosis, meiotic drive, recombination
(University of Missouri, Agricultural Experiment Station, 1979)
Several lines of research have been stimulated because the direct results of Mendelian segregation are apparent in Neurospora asci. Spore killer genes provide an example. When across is heterozygous for Spore killer, four ...
Role of gene duplication in the evolution of complex physiological mechanisms : an assessment based on protein sequence data : (gene duplication, protein sequences, evolutionary trees, serine proteases, immunoglobulins, evolution of muscle types)
(University of Missouri, Agricultural Experiment Station, 1979)
Genetic duplication has played a major role in the evolution of physiological complexity by creating originally redundant genes that evolved to produce related proteins in the organism. The related chains of certain polymeric ...
The role of tRNA in development
(University of Missouri, Agricultural Experiment Station, 1972)
Experiments that suggest a developmental regulatory role for tRNA in translation (such cytokinins in tRNA, suppressor mutations, tRNA methyases, excessive number of isoaccepting species, and others) are briefly presented. ...
Evolution and genetic significance of mitochondria
(University of Missouri, Agricultural Experiment Station, 1972)
Mitochondria are constituted of two different membrane systems which may well have quite different origins in replication and evolution. It is hypothesized that the outer membrane is entirely derived from cytosol constituents ...
The genetics of corn breeding
(University of Missouri, Agricultural Experiment Station, 1972)
Hybrid corn has now replaced open-pollinated varieties almost completely. This change-over has been accompanied by a nearly 3-fold increase in U.S. average yields. The genetic basis for corn breeding rests upon classical ...
Genetics of psychoses
(University of Missouri, Agricultural Experiment Station, 1972)
The financial burden of the psychoses each year runs into the billions of dollars while the misery to everyone concerned is beyond calculation. It should be self-evident that the genetics of the psychoses is therefore a ...
Seven or twenty-seven against obscurity or still further observations on tittlebats
(University of Missouri, Agricultural Experiment Station, 1972)
Trends in genetics research--prospects for development
(University of Missouri, Agricultural Experiment Station, 1972)
Some aspects of current research are viewed in an attempt to anticipate major trends in the next few years. The observations indicate that geneticists in general are becoming more problem - than organism-oriented and are ...
Chromosome engineering in wheat
(University of Missouri, Agricultural Experiment Station, 1972)
Three methods have been developed for the transfer of genetic material to wheat chromosomes from alien chromosomes: (i) Use of ionizing radiation to translocate an alien segment. (ii) Induction of homoeologous pairing, ...
The biochemisrty of meiosis and genetic recombination
(University of Missouri, Agricultural Experiment Station, 1972)
Evidence is presented for three important DNA metabolic processes which may direct genetic recombination events during meiosis. These processes are: 1) DNA breakage and repair, 2) facilitated interaction between homologous ...
Extension of BrdU-dye analysis of DNA replication and sister chromatid exchange formation to in vivo systems : (in vivo, BrdU-dye, DNA replication, sister chromatid exchange)
(University of Missouri, Agricultural Experiment Station, 1977)
BrdU-dye methodology was initially developed in tissue culture. Wide application of the technique for cytogenetic studies of DNA structure, replication and repair followed. Although the need for parallel in vivo studies ...
Genetics of nitrogen fixation : (nitrogenase, molybdenum, ammonium excretion, legumes)
(University of Missouri, Agricultural Experiment Station, 1977)
Recent advances in understanding the genetics of nitrogen fixation have provided ideas for novel application of nitrogenase and nitrogen-fixing organisms. Mutant strains have been useful for identifying the active site of ...
Genetic transformation as a tool in the studies of DNA replication and recombination
(University of Missouri, Agricultural Experiment Station, 1975)
Mechanism of chromosome replication by the use of transformation and genetic recombination are reviewed in Bacillus subtilis. The order of gene replication can be determined by marker frequency analysis during exponential ...
Genetic analysis of photosynthesis
(University of Missouri, Agricultural Experiment Station, 1975)
It is now possible to select mutations of nuclear genes controlling various steps of the light reaction of photosynthesis in higher plants. Forty-nine such mutants, which were not previously available for the study of ...
Evolutionary importance of gene regulation
(University of Missouri, Agricultural Experiment Station, 1975)
To assess the relative importance of regulatory mutations and structural gene mutations in adaptive evolution at the organismal level, two kinds of evidence were considered: 1) Evidence concerning the mechanism by which ...
Eugenics revisited : the case for germinal choice
(University of Missouri, Agricultural Experiment Station, 1973)
Tryptohan photoproduct as a genetic probe : effects on bacteria
(University of Missouri, Agricultural Experiment Station, 1973)
Recombinationless (rec) mutants of bacteria are sensitive to visible and near-ultraviolet wavelengths of light. In addition, these mutants are sensitive to a tryptophan photoproduct that results from irradiation of this ...
Mutagenic mechanisms in bacteriophage T4 : (bacteriophage T4, mutagenic mechanisms, heat mutagenesis)
(University of Missouri, Agricultural Experiment Station, 1976)
Mutagenic mechanisms can be divided into two categories, those dependent upon specific base mispairing (generating base pair substitutions and frameshift mutations) and those dependent upon misrepair (perhaps as a result ...
RNA : protein and protein : Protein interactions in the virions of southern bean mosaic virus : (isometric plant viruses, stabilizing interactions, capsid structure)
(University of Missouri, Agricultural Experiment Station, 1976)
Virions of southern bean mosaic virus (SBMV), a small RNA-containing isometric plant virus, are stabilized with strong linkages between the coat protein subunits mediated through divalent metal ions (magnesium, calcium) ...