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Genetically Engineered Swine Models to Study Diseases like Cystic Fibrosis
Swine have become important in biomedical research as they are excellent models for a variety of diseases including cardiovascular disease, atherosclerosis, cutaneous pharmacology, wound repair, cancer, diabetes, ophthalmology, ...
Commercialization of novel biomarkers of male fertility in humans and farm animals
Each year, US infertility clinics treat 135,000 couples who fail to conceive naturally. Up to 40% of these infertility cases can be attributed to male infertility stemming from poor sperm quality. An additional 20% of ...
High-throughput genomics and the Sword of Damocles
Next-generation sequencing and high-throughput assaying technologies have dichotomized entire research communities into those individuals who have rapidly evolved in response to the technological selection pressure and ...
Swine models of Human Conditions
Since the introduction of Dolly, the first cloned sheep, genetic engineering of livestock has advanced to the point that nearly any genetic modification appears feasible. Genes can be introduced, deleted or altered in ...