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Assessing the biocompatibility of different sizes and concentrations of gold nanoparticles conjugated to decellularized tissue scaffolds
(University of Missouri--Columbia, 2016)
Gold nanoparticles conjugated to decellularized scaffolds have been studied previously within the fields of tissue engineering and biomaterials. They hold much potential for applications in soft tissue repair and improved ...
Clinical translation of nanomaterials for early detection of genetic abnormalities in fetus and retinopathy in neonates and adults
(University of Missouri--Columbia, 2017)
Nuclear medicine covers a wide variety of radionuclides to meet demands of disease. In the current study, first we have looked at the application of mono-amine mono-amide ligands for Re(V), 99mTc(V), and 186Re(V) with ...
Climate change impacts on hydrologic components and occurrence of drought in an agricultural watershed
(University of Missouri--Columbia, 2018)
The study on potential acceleration of future hydrologic cycle due to change in precipitation and increase in temperature are essential for managing natural resources and setting policy. The impact of future climate change ...
Evaluation of a solid-liquid manure separation operation
(University of Missouri--Columbia, 2018)
Field monitoring and laboratory tests were conducted to evaluate the efficacy and practicality of a solid-liquid separation barn for finishing pigs. The solid-liquid separation system included a mechanical scraper and ...
A continuous-wave-based acoustic method to measure viscoelastic properties of materials
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Typical viscoelastic materials do not have a flat frequency response to mechanical vibrations. Viscoelastic property evaluations with a multi-frequency ...
Porous silicates for applications in smart water treatment systems and antimicrobial biomedical coatings
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Porous silicates, particularly ordered ones, may find novel and wide-ranging applications in the bioengineering arena in the near future. For instance, ...
Use of geographic information systems and remote sensing as automated tool for variable rate irrigation prescriptions
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Economic as well as water shortage pressure on agricultural use of water has placed added emphasis on efficient irrigation management. Center pivot ...
Prediction of knee loading in native knee and total knee arthroplasty : a forward dynamics computational study
(University of Missouri--Columbia, 2019)
"The goal of this dissertation is to develop a musculoskeletal model and corroborate model predictions to experimentally measured in vivo knee contact forces, in order to study the biomechanical consequences of two different ...
Targeted therapeutics for non small cell lung carcinoma
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] "Lung carcinoma, also known as lung cancer, is a malignant tumor of lungs characterized by uncontrolled call growth in lung tissue. Tobacco smoking ...
Imaging structural and mechanical properties of articular cartilage using optical polarization tractography
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Osteoarthritis (OA) is an extremely common joint disease, which affects more than one-third of all adults in the USA. Although the entire joint ...
Studying pupillary light reflex in young children with autism spectrum disorders
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Pupillary light reflex (PLR) is a phenomenon wherein the pupil size changes according to retina illumination. PLR of adults and children has been ...
Engineering target nanomaterials for stable and efficient delivery of siRNA
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Lung cancer has the highest cancer-related mortality rate in the United States. The most common form of lung cancer is non-small cell lung ...
Tnf[alpha] alters occludin and endothelial cell barrier function : role of p38MAPK
(University of Missouri--Columbia, 2016)
Occludin is one of the key tight junction (TJ) proteins in endothelial cells and it plays an important role in modulating blood brain barrier (BBB) function. This protein (65kDa) has been shown to engage in many signaling ...
Automatic four-limb IMU gait analysis in the canine DMD model
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Gait analysis is valuable for studying neuromuscular and skeletal diseases. Wearable motion sensors or inertial measurement units (IMUs) possess ...
Integrating nanostructured artificial receptors with whispering gallery mode optical microresonators via inorganic molecular imprinting techniques
(University of Missouri--Columbia, 2016)
The creation of label-free biosensors capable of accurately detecting trace contaminants, particularly small organic molecules, is of significant interest for applications in environmental monitoring. This is achieved by ...
Natural and synthetic materials for the regeneration of osseous tissue
(University of Missouri--Columbia, 2017)
Bone is a complex tissue with many regulation mechanisms which can be taken advantage of through the release of simple signaling molecules delivered via a biodegradable material like a hydrogel. Hydrogels are water swollen ...
Nanocellulose extraction and surface modification toward active packaging applications
(University of Missouri--Columbia, 2017)
Cellulose nanocrystals (CNCs) have attracted growing interest as a renewable nanomaterial. The main objective of this study was to explore the extraction of CNCs from switchgrass and surface modification of CNCs into ...
Electrospinning lecithin-polycaprolactone scaffolds with gold nanoparticles for osteoarthritis prevention
(University of Missouri--Columbia, 2018)
The human body has articular cartilage covering the ends of the bones to act as a shock absorber and aid in movement. In a disease state, this articular cartilage breaks down causing pain, swelling, and stiffness. With ...
The role of Pre-B-cell colony-enhancing factor in neuronal death after ischemia and motor dysfunction
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Pre-B-cell colony-enhancing factor (PBEF) is the rate-limiting enzyme in the salvage pathway of mammalian nicotinamide adenine dinucleotide (NAD+) ...
Modeling and optimization of the Mannheimia haemolytica vaccine production process
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Leukotoxin (Lkt) from Mannheimia haemolytica has been discovered as the primary pathogenic factor for bovine respiratory disease (BRD), causing huge ...