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Characterization of the relationship between radiographic grading and biomarkers in patients with knee osteoarthritis
(University of Missouri--Columbia, 2020)
"Osteoarthritis (OA) is a whole-joint degenerative disease, affecting more than 25% of the adult population. Currently, OA is most commonly diagnosed based on radiographic documentation. However, radiographic grading is ...
Novel approach to assessment of efficacy of platelet inhibition by clopidogrel and aspirin in healthy dogs
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Introduction: Antiplatelet therapy, including clopidogrel and aspirin, is used to decrease the risk of thromboembolism in dogs. However, ...
Intervertebral discs : metabolic responses to load, injury, and pro-inflammatory stimulation
(University of Missouri--Columbia, 2020)
Introduction: Intervertebral disc (IVD) degeneration is a significant cause of back pain and disability. Factors such as trauma and magnitude and frequency of loading are associated with IVD degeneration. However, the ...
Impact of selective motor neuron death on hypoglossal motor neuron survival and tongue morphology in a novel model of dysphagia
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Amyotrophic lateral sclerosis (ALS) is a devastating disease characterized by the progressive loss of motor neurons and paralysis of the muscles they ...
Tales of an 'invisible' life stage : survival and physiology among terrestrial juvenile ambystomatid salamanders
(University of Missouri--Columbia, 2019)
The vital rates (e.g., survival, growth, and reproduction) of distinct life stages within a species are known to influence the growth and persistence of populations. As such, studies describing stage-specific vital rates, ...
Mechanisms of polar growth in the alphaproteobacterial order rhizobiales
(University of Missouri--Columbia, 2019)
All bacteria elongate and divide to faithfully reproduce their cell shape. Understanding the mechanisms that drive bacterial morphology requires an intimate knowledge of how the cell wall is synthesized. During cell ...
Development of an amenable system for site-specific addition to a maize chromosome
(University of Missouri--Columbia, 2019)
Currently, transgenic maize is produced by random integration of a transgenes into the plant. This works for single genes, but not as well for multiple traits. Identifying plants that contain several transgenes becomes a ...
Identification, characterization and use of novel thermogenetic tools in drosophilia melanogaster
(University of Missouri--Columbia, 2019)
Extrinsic control of neural activity is necessary to decipher the neural mechanisms underlying behavior. Molecular tools that employ light (optogenetics) or temperature (thermogenetics) are primarily used for extrinsic ...
Low-level laser therapy for the treatment of osteoarthritis in the dog
(University of Missouri--Columbia, 2020)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] In veterinary medicine there is increasing interest in the use of low-level laser therapy (LLLT) for the treatment of pain in dogs with OA. ...