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Polystyrene coated iron-platinum drug delivery platforms for theranostics
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Cancer is the second leading cause of death in the United States, exceeded only by heart disease, and it is estimated that one in every four deaths is ...
Deep ultraviolet resonance Raman spectroscopy as a tool for biomolecule analysis
(University of Missouri--Columbia, 2017)
Cholesterol is a major component of membranes, reducing their fluidity at higher concentrations. The UV Raman vibrational mode of the carbon-carbon double bond in cholesterol occurs at 1675 cm-1 is strongly resonance ...
Mechanistic and computational studies of ferroin, simple organic acids, and bromine oxides : elucidating the complex electrochemical dance in an oscillating reaction
(University of Missouri--Columbia, 2016)
Before the year 1950, many chemists in their 'right mind' held the archaic belief that all chemical reactions proceed strictly from reactants to products, though some could be coaxed into reverse. What we now know colloquially ...
Economical synthesis of carbon nanoparticles
(University of Missouri--Columbia, 2016)
One of the core values of a capitalistic market is cost efficiency which is tried and true even in cursed with discovering and developing materials as inexpensive as possible. Now, this is for a multitude of reasons but ...
Gold-catalyzed generation of vinylthionium ions and the development of an organocatalytic, asymmetric (4+3)-cycloaddition reaction
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] An allylic benzoate ester was prepared and used as a progenitor of vinylthionium ions for (4+3)-cycloaddition reactions. The chemistry was limited to ...
Sustainable chemical approaches to two-dimensional nanosheets and mesoporous platforms and catalysts
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Green Chemistry, also called as Sustainable Chemistry, envisions minimum hazard to improve the efficiency and performance of materials while designing ...
Synthesis and photochemistry of PT (IV) hydroxo complexes
(University of Missouri--Columbia, 2015)
Global energy consumption and the production of clean renewable energy have become greater challenges. Sunlight-induced splitting of water into H2 and O2 is one of the leading strategies to achieve clean and renewable ...
Synthesis and properties of small molecules designed to covalently capture native and oxidized forms of protein tyrosine phosphatase 1B (PTP1B)
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Protein tyrosine phosphatase 1B (PTP1B) is a validated target for the treatment of type 2 diabetes and obesity. The discovery of selective inhibitors ...
Spectroscopic investigation of the effect of polyphenolic compounds on the amyloid-[beta] protein
(University of Missouri--Columbia, 2017)
Aggregation of the amyloid-[beta] (A[beta]) protein is associated with the development of Alzheimer's disease. A[beta] is a 39-43 residue cleavage product of the amyloid precursor protein (APP). A[beta] aggregates to produce ...
The use of polyhedral borane derivatives as molecular electronic scaffolds
(University of Missouri--Columbia, 2016)
When functionalized, the highly symmetrical, three-dimensional aromatic cluster, closo - dodecahydrododecaborate, or dodecaborate, has a two, one - electron oxidation pathway available to it. The framework of dodecaborate ...
Synthesis and characterization of pn monoanionic ligands and their reactivity with actinides
(University of Missouri--Columbia, 2021)
Organoactinide complexes have gained much popularity in the recent decades particularly in the field of nuclear waste sequestration. With the increase of nuclear power along side other residual nuclear waste from power ...
Development of highly selective fluorescent sensors for detection of glycolipids in vesicles and visualization of glutamate for neuronal imaging
(University of Missouri--Columbia, 2020)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI-COLUMBIA AT REQUEST OF AUTHOR.] Fluorescent sensors are very useful tools for exploring chemical biology and advanced medical research. Herein, we propose four different ...
Design and gas sorption study of c-alkylresorcin[n]arene-based cocrystals
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Supramolecular chemistry is the study of how to form complexes through molecular self-assembly and intermolecular bonding. Our research group has been ...
The coloring matter in fat from cow's milk
(University of Missouri--Columbia, 1910)
Text from page 1: The great variety of coloring matters that exist throughout the entire plant and animal kingdoms have long been of interest to scientists. From the standpoint of both the chemist and the physiologist a ...
Technetium and rhenium (I and V) complexes for radiopharmaceutical applications
(University of Missouri--Columbia, 2016)
Technetium and rhenium have radioactive isotopes that are clinically useful for diagnostic (Tc-99m) or therapeutic (Re-186/188) purposes. This makes them attractive candidates for incorporation into pharmaceuticals. One ...
Finite element analysis for the insertion process of the press-fitted total hip arthroplasty
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] There are more than 300,000 total hip arthroplasty (THA) surgeries performed every year in the United States. Press-fitted artificial hip joints are ...
The synthesis of a fluorescent bioconjugation agent
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Bioconjugation linkers are used covalently link two molecules, where at least one is a large biomolecule for uses such as tracking cellular function, ...
Synthesis design and nuclear medicine applications for radiometal, beta and gamma emission, chelated complexes /
(University of Missouri--Columbia, 2017)
Nuclear medicine covers a wide variety of radionuclides to meet demands of disease. In the current study, first we have looked at the application of mono-amine mono-amide ligands for Re(V), 99mTc(V), and 186Re(V) with ...
Near infrared fluorescent sensors and their use in vivo /
(University of Missouri--Columbia, 2017)
In an effort to design near-infrared (NIR), water soluble glucose sensors, several pH sensitive NIR cyanine derivates were designed and synthesized to provide insight into the viability of the cyanine platform as the ...
Synthesis and reactivity of actinide phosphorano-stabilized carbene and phosphido complexes
(University of Missouri--Columbia, 2018)
Nuclear power plants have been operated in the United States for over 60 years, generating over 800 terawatt-hours of energy per year. However, there is still no reliable process to recycle the spent nuclear fuel. This ...