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Role of P2Y₂ nucleotide receptors in reactive astrogliosis
(University of Missouri--Columbia, 2005)
Astrocytes become activated in response to brain injury characterized by increased expression of GFAP and increased rates of cell migration and proliferation. Damage to brain cells causes the release of cytoplasmic ...
Regulations and functions of P2Y₂ and P2X₇ nucleotide receptors in the central nervous system
(University of Missouri--Columbia, 2007)
It is well known that ATP acts as a classic neurotransmitter in the central nervous system. It is stored in synaptic vesicles, released upon neuronal excitation, and activates both ion channel receptors (P2X) and G ...