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Role of Redox-Active Trace Metal (RATM) Oxidants in the Regulation of Toll-Like Receptor 4 (TLR4) Signaling-Mediated Inflammatory Phenotype in Synovial Fibroblasts
(University of Missouri -- Kansas City, 2018)
While the involvement of oxidant stress in rheumatoid arthritis (RA) has been
suspected, the role of redox-active trace metals (RATM) as exogenous pro-oxidants in the
pathogenesis of RA has not yet been investigated. ...
Role of Toll-Like Receptor 4 in Oxidant-induced Inflammatory Phenotypes in Macrophages
(University of Missouri--Kansas City, 2017)
A common mechanism by which redox stress may activate inflammatory
responses to potentially initiate, propagate and maintain many diseases states has not
been characterized. Accumulating evidence suggests that pattern ...