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Now showing items 1-17 of 17
Genome-wide microbial phylogeny reconstruction with polytomy identification
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Evolutionary comparative genomics is one of the most studied areas in the computational biology. With ever increasing speed of newly sequenced microbial ...
Bioinformatics analysis and prediction of protein phosphorylation and other posttranslational modifications
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Protein posttranslational modifications (PTM), such as phosphorylation, play essential roles in many aspects of cell life. With the rapid accumulation ...
Methods for protein structure prediction
(University of Missouri--Columbia, 2014)
Develpment of soybean knowledge base for systems biology studies
(University of Missouri--Columbia, 2014)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Soybean (Glycine max), as an important crop worldwide primarily for protein and oil, has raised great interest in both basic and applied researches. ...
Computational methods for bacterial characterization and bacteria-host/environment interaction analyses
(University of Missouri--Columbia, 2012)
With the rapid development of next-generation sequencing technologies, bacterial identification becomes a very important and essential step in processing genomic data, especially for metagenomic data. Many computational ...
Using pathway correlation profiles for understanding pathway perturbation
(University of Missouri--Columbia, 2012)
Identifying perturbed or dysregulated pathways is critical to understanding the biological processes that change within an experiment. Previous methods identified important pathways that are significantly enriched among ...
Development of tools for SoyKB: SNPViz, differential expression and protein bioviewer
(University of Missouri--Columbia, 2014)
Soybean Knowledge Base (SoyKB) is a comprehensive website, which contains lots of web sources for soybean. By integrating multi omics data and solving data storage problem, SoyKB is able to build connection between multiple ...
Development of Soybean Knowledge Base (SoyKB), a multi-omics data integration web resource for bridging molecular breeding and translational genomics in Glycine Max
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Many genome-scale data are available in soybean (Glycine Max) including genomics, transcriptomics, proteomics and metabolomics datasets, together with ...
Analyzing high-throughput genomics data for cancer studies
(University of Missouri--Columbia, 2015)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] NGS data output has increased at a rate that outpaces Moore's law, more than doubling each year since it was invented. Studying such high-throughput ...
Phosphoprotein analysis of soybean root hairs in response to Bradyrhizobium japonicum inoculation
(University of Missouri--Columbia, 2012)
The nitrogen fixing symbiosis in soybean (Glycine max) is initiated by colonization of root hairs by the symbiotic bacterium Bradyrhizobium japonicum. Specificity in this symbiosis is determined very early during the initial ...
Development of a plant protein phosphorylation database and a web-based protein phosphorylation prediction tool
(University of Missouri--Columbia, 2012)
In this project, two efficient and intuitive user-interfaces were designed and developed to be highly accessible and versatile for bioinformatics researchers. Two web based user interfaces were designed for two bioinformatics ...
Protein structural models selection using 4-mer sequence and combined single and consensus scores
(University of Missouri--Columbia, 2012)
Quality assessment for protein structure models is an important issue in protein structure prediction. Consensus methods assess each model based on its structural similarity to all the other models in a model set, while ...
Computational analysis of tongue image for health diagnosis
(University of Missouri--Columbia, 2017)
Tongue, the primary taste organ in the mouth, can reflect the whole body's health conditions based on the Traditional Chinese Medical (TCM) theories. Watching the tongue is one of the most common, essential and reliable ...
Applications of deep neural networks to protein structure prediction
(University of Missouri--Columbia, 2018)
Protein secondary structure, backbone torsion angle and other secondary structure features can provide useful information for protein 3D structure prediction and protein functions. Deep learning offers a new opportunity ...
Protein transport : bioinformatics methods for understanding protein subcellular localization
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Eukaryotic cells contain diverse subcellular organelles. These organelles form distinct functional cellular compartments where different biological ...
Data analysis and prediction of protein posttranslational modification
(University of Missouri--Columbia, 2014)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Protein posttranslational modification (PTM) occurs broadly after or during protein biosynthesis, to assist folding or activate function during the ...
Complexity reduction and visualization tool for RDF knowledge network application in precision medicine
(University of Missouri--Columbia, 2015)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Precision medicine is one of the most rapidly emerging areas of research and development, crucial for improving patient care, but there is a lack of ...