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Extension of BrdU-dye analysis of DNA replication and sister chromatid exchange formation to in vivo systems : (in vivo, BrdU-dye, DNA replication, sister chromatid exchange)
(University of Missouri, Agricultural Experiment Station, 1977)
BrdU-dye methodology was initially developed in tissue culture. Wide application of the technique for cytogenetic studies of DNA structure, replication and repair followed. Although the need for parallel in vivo studies ...
Genetics of nitrogen fixation : (nitrogenase, molybdenum, ammonium excretion, legumes)
(University of Missouri, Agricultural Experiment Station, 1977)
Recent advances in understanding the genetics of nitrogen fixation have provided ideas for novel application of nitrogenase and nitrogen-fixing organisms. Mutant strains have been useful for identifying the active site of ...
Historical aspects and significance of the discovery of wild wheats : (origin of wheat, evolution, gene pools)
(University of Missouri, Agricultural Experiment Station, 1977)
The genetic complexity of the R locus in maize : (gene complex, regulatory elements, paramutation)
(University of Missouri, Agricultural Experiment Station, 1977)
The evidence on the compound structure of the R locus is reviewed. The more recent analysis of another group of R accessions, collectively known as R-cherry, seems to indicate that this locus is a gene cluster separable ...
A gene-enzyme relationship in neurospora : (neurospora, complementation, amino acid substitutions, chain termination, suppression, osmotic repair)
(University of Missouri, Agricultural Experiment Station, 1977)
The results of work on amino acid replacements in NADP-specific glutamatede hydrogenase of Neurospora crassa, due to mutation in the am gene, are reviewed: amino acid residues which are important in coenzyme binding and ...
On the organization of DNA in isolated bacterial chromosomes : (bacterial DNA, folded chromosomes, EM, RNA)
(University of Missouri, Agricultural Experiment Station, 1977)
We review physical studies and electron microscopy of membrane-free folded chromosomes from E. coli [Kavenoff and Bowen, Chromosoma 59, 89 (1977)], and we consider the apparent relation between the organization of the DNA ...
Chromatin as a model system for studying the regulation of histone gene expression in mammalian cells : (mRNA, chromosomal proteins, transcription, cell cycle)
(University of Missouri, Agricultural Experiment Station, 1977)
Histone gene expression was studied during the cell cycle of continuously dividing HeLa S3 cells and after stimulation of confluent monolayers of WI-38 human diploid fibroblasts to proliferate. The presence of histone mRNA ...
Analysis of gene number and development in polygenic systems : (polygenes, variation, selection, pattern)
(University of Missouri, Agricultural Experiment Station, 1977)
The assumption that quantitative variation is produced by a large number of genes is re-examined. In fact, one finds that often only a small number of loci are involved. This, therefore, opens to careful study the developmental ...
A genetic pathway for dauer larva formation in caenorhabditis elegans : (nematode, development, neuron)
(University of Missouri, Agricultural Experiment Station, 1977)
C. elegans is a roundworm, a free-living soil nematode. The dauer larva is a non-feeding, non-growing larval stage which is formed under conditions of starvation. It possesses a relatively impermeable cuticle and differs ...
Polypeptide composition of fraction I protein as an aid in the study of plant evolution : (chloroplast DNA, age of genera and species, origin of genomes, composition of proteins as affected by amphiploidy)
(University of Missouri, Agricultural Experiment Station, 1977)
Fraction 1 protein (F-1-P), found in all green plants, consists of eight large subunits (LS) coded by chloroplast DNA and eight small subunits (SS) coded by nuclear DNA. By electrofocusing in 8M urea many different species ...
The role of tRNA in development
(University of Missouri, Agricultural Experiment Station, 1972)
Experiments that suggest a developmental regulatory role for tRNA in translation (such cytokinins in tRNA, suppressor mutations, tRNA methyases, excessive number of isoaccepting species, and others) are briefly presented. ...
Evolution and genetic significance of mitochondria
(University of Missouri, Agricultural Experiment Station, 1972)
Mitochondria are constituted of two different membrane systems which may well have quite different origins in replication and evolution. It is hypothesized that the outer membrane is entirely derived from cytosol constituents ...
Genetics of psychoses
(University of Missouri, Agricultural Experiment Station, 1972)
The financial burden of the psychoses each year runs into the billions of dollars while the misery to everyone concerned is beyond calculation. It should be self-evident that the genetics of the psychoses is therefore a ...
Seven or twenty-seven against obscurity or still further observations on tittlebats
(University of Missouri, Agricultural Experiment Station, 1972)
Trends in genetics research--prospects for development
(University of Missouri, Agricultural Experiment Station, 1972)
Some aspects of current research are viewed in an attempt to anticipate major trends in the next few years. The observations indicate that geneticists in general are becoming more problem - than organism-oriented and are ...
The genetics of corn breeding
(University of Missouri, Agricultural Experiment Station, 1972)
Hybrid corn has now replaced open-pollinated varieties almost completely. This change-over has been accompanied by a nearly 3-fold increase in U.S. average yields. The genetic basis for corn breeding rests upon classical ...
Chromosome engineering in wheat
(University of Missouri, Agricultural Experiment Station, 1972)
Three methods have been developed for the transfer of genetic material to wheat chromosomes from alien chromosomes: (i) Use of ionizing radiation to translocate an alien segment. (ii) Induction of homoeologous pairing, ...
The biochemisrty of meiosis and genetic recombination
(University of Missouri, Agricultural Experiment Station, 1972)
Evidence is presented for three important DNA metabolic processes which may direct genetic recombination events during meiosis. These processes are: 1) DNA breakage and repair, 2) facilitated interaction between homologous ...
General genetic recombination in bacteriophage T4 : DNA exchange, DNA- protein-protein interactions
(University of Missouri, Agricultural Experiment Station, 1979)
We will discuss current models of genetic recombination emphasizing their general aspects and the specific points which have been demonstrated in phage T4. Recombination in this phage occurs preferentially (although not ...
Genetics and molecular biology of plastids of higher plants : plastids in male gametes, mutation induction, nitroso - urea, plastid mutants, thylakoid proteins, plastid ribosome deficiency, pollen, chloroplast, photosynthesis, mitochondria
(University of Missouri, Agricultural Experiment Station, 1979)
In the majority of angiospermous species the plastids are excluded from the generative or sperm cells during the first pollen mitosis or during pollen development; this is the basis of the maternal inheritance of plastid ...