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Development of a biosensor for the detection of Helicobacter hepaticus utilizing multi-functioning immobilization platforms
(University of Missouri--Columbia, 2010)
Optical biosensor development is a process involving the careful selection of the material for the immobilization platform, design of the detection mechanism and integration with optical and electronic equipment. The ability ...
Functional study of Kcv potassium channel through manipultion [sic] of individual subunits
(University of Missouri--Columbia, 2010)
Potassium channels make up a ubiquitous, physiologically essential class of integral membrane proteins. Many K+ channels contain four identical symmetrically associated subunits. To explore the role of an individual subunit ...
Amyloid- [beta] peptide induces temporal membrane biphasic changes in astrocytes through cytosolic phospholipase A₂
(University of Missouri--Columbia, 2010)
Oligomeric amyloid-[beta] peptide (A[beta]) is known to induce cytotoxic effects and damage cell functions in Alzheimer's disease. However, mechanisms underlying the effects of A[beta] on cell membranes have yet to be fully ...
Manure management using precision agriculture
(University of Missouri--Columbia, 2010)
The overall purpose of this project was to develop and implement a manure application record system that was solely based on Global Positioning Systems (GPS). This system will have the ability to provide steering and ...
Molecularly imprinted polymer labeled with quantum dots for detection of nitroaromatic explosives
(University of Missouri--Columbia, 2010)
A sensing device for explosive compounds is a fundamental step towards the capability to detect the presence of landmines, improvised explosive devices (IEDs), and other unexploded ordinance. To detect high explosive ...
Applications of the opto-fluidic ring resonator for DNA methylation analysis and microfluidic laser development
(University of Missouri--Columbia, 2010)
For several decades, optical ring resonators have played an important role in the field of telecommunications. Within only the past decade however, ring resonators have been applied for the purposes of biological and ...
Geographic information systems used for precision agriculture : knowledge and use by agriculture students at the University of Missouri (MU)
(University of Missouri--Columbia, 2010)
The use of GIS in PA technology helps manage the information intensive environment in production agriculture by intertwining site-specific (within field) management with computer software modeling for analyses and ...
Development of land-use map for Salt River basin using satellite imagery
(University of Missouri--Columbia, 2010)
The Salt River Basin in northeastern Missouri is the major water supply source for people in the region. There is a need to build a long term simulation and to validate the long term trend of pollutant concentrations in ...
Development of a fluorescence-based protease biosensor using nanoscale platforms
(University of Missouri--Columbia, 2010)
The development of a protease biosensor utilizing nanomaterials is presented in this dissertation. Peptide substrates and nanomaterial platforms were investigated to increase the sensitivity and response time for the ...
Development of an online planning tool for designing terrace layouts
(University of Missouri--Columbia, 2010)
A web-based conservation planning tool for terrace layouts was created by modifying a terrace location program (TERLOC), developed originally by Sudduth and Gregory (1982) and revised by Ghidey et al. (1992). Development ...
Time delay compensation in finite-order models of acoustic wave propagation in homogenous media
(University of Missouri--Columbia, 2011)
Finite-order models do not completely account for the delay in acoustic wave propagation and thus require an additional phase correction, besides parameter adjustments to fit experimental measurements. As a consequence, ...
Microfluidic capture of rare cells via non-cylindrical microposts in an array
(University of Missouri--Columbia, 2014)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] In recent decades, microsystems for the capture of rare cells have become exceedingly popular and important in the study of cellular mechanisms. These ...
Plasmonic-enhanced fluorescent conjugated polymer chemosensor for ultra-sensitive detection of nitroaromatic vapors
(University of Missouri--Columbia, 2014)
Rapid degradation of fluorescent conjugated polymers in ambient conditions imposes severe restrictions on their utility for long-term, portable sensing applications. This dissertation discusses the combined use of low-density, ...
Vascular smooth muscle calcium waves in isolated arterioles : interactions between intraluminal pressure and intracellular calcium handling
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Arterioles, an important control element in the circulatory system regulate blood flow in part though a phenomenon known as the 'Myogenic Response'. ...
The role of metabotropic glutamate receptor 5 in cerebral ischemia
(University of Missouri--Columbia, 2014)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Group I metabotropic glutamate receptor 5 (mGluR5), belongs to G-protein coupled receptors family and plays important roles in CNS disorders including ...
Azelnidipine attenuates inflammatory responses, siperoxide and relevant signaling pathways induced by amyloid-beta in mouse cerebral endothelial cells
(University of Missouri--Columbia, 2014)
Alzheimer's disease (AD) is a debilitating neurodegenerative disease with no known cure. The cause and progression of AD is still unclear. Over the years, studies have shown that one of the earliest cytotoxic effects is ...
Microrna detection by surface plasmon resonance
(University of Missouri--Columbia, 2014)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Lung cancer is the leading cause of cancer death in the world out of over 100 different known human cancers. Therefore there is a need for better ...
Evaluation of the antimicrobial properties and biocompatibility of polypropylene mesh conjugated with gold nanoparticles
(University of Missouri--Columbia, 2013)
Polypropylene (PP) mesh is commonly utilized as a patch for hernia repairs and for pelvic slings. However, biocompatibility and infection rates are a concern. Conjugating gold nanoparticles (AuNPs) to PP mesh may enhance ...
Employers perceptions of agricultural systems management (ASM) graduates competencies and skill level in the work environment
(University of Missouri--Columbia, 2012)
The University of Missouri Agricultural Systems Management and Agricultural Engineering Extension program is undergoing a six year review in order to evaluate whether or not the department is satisfying the needs of the ...
Multi-frequency electrical impedance method for detection of viable micro-organisms, their quantification and their characterization
(University of Missouri--Columbia, 2013)
Despite advances in DNA based technologies and molecular methods, there are still several drawbacks to these methods and hence, there is a need for development of a new technology for microbial detection and quantification. ...