Search
Now showing items 1-20 of 67
Phylogenomics of ancient whole genome duplications in the Brassicales
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Ancient whole genome duplications (WGDs), which multiply copies of the entire genome within an organism, are ubiquitous throughout the evolutionary history of higher eukaryotic...
The evolution of Brassica crops and wild relatives: phylogenetics, development and domestication
(University of Missouri--Columbia, 2012)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The main goal of my dissertation is to understand the patterns and mechanisms underlying mustard (tribe Brassiceae, Brassicaceae) speciation in the Mediterranean while...
A study of reproductive toxicology
(University of Missouri--Columbia, 2012)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Di(2-ethylhexyl) phthalate (DEHP) is a ubiquitous environmental contaminant. Epidemiological studies suggest that DEHP decreases masculinization of male fetuses. Numerous rat...
Fetal exposure to low but not high doses of Bisphenol A (BPA) increases abdominal fat, impairs glucose tolerance and alters serum hormones in male mice : evidence for non-monotonic dose-response relationships
(University of Missouri--Columbia, 2012)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Bisphenol A (BPA) is a ubiquitous contaminant with estrogenic and other hormonal activities. A criticism of many experimental studies is the lack of examination of a wide does...
The characterization of the tetratricopeptide repeat protein 13 in mammals
(University of Missouri--Columbia, 2012)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Tetratricopeptide repeat domain protein 13 (TTC13) is a member of a large family of proteins known as tetratricopeptide repeat (TPR) proteins that has more than 5,000 members...
Immunogenic properties of neuralized embryonic stem cells in a model of allogenic intracranial transplantation
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Intracranial stem cell transplantation has may restore central nervous system (CNS) function and compensate for neural cell loss. However, immunological rejection of stem cells...
The eco-physiology of PHOT1/phot1[delta]PKD, insights into a phototropically enhanced mutant.
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The phototropin class of blue light photoreceptors in Arabidopsis is critical to how plants response to light cues. Here, I study how the photo-perception process occurs...
Mitochondrial DNA insertions in the nuclear genomes of maize (Zea mays ssp. mays)
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Mitochondria were derived from once free--living [alpha]-proteobacteria and became part of eukaryotic cells through endosymbiosis (Kleine et al. 2009). The movement...
Neuromodulation-dependent regulation of coordinated patterns of gene expression in motor neurons of the stomatogastric ganglion
(University of Missouri--Columbia, 2012)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The pyloric network of the crustacean stomatogastric ganglion (STG) is a central pattern generator that requires descending modulation for normal ongoing rhythmic activity...
A tale of two horses : origins and population genetics of two feral horse herds
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Domestic feral horses have been living on two United States barrier islands since earliest record, and their origins are speculative. Legend holds that horses surviving Spanish...
Understanding the effects of maternal undernutrition in early gestation on placental development in late gestation
(University of Missouri--Columbia, 2018)
that maternal periconceptional food restriction until mid- gestationaffected formation of blood spaces within the labyrinthine placenta near term, ascompared to those from control-fed dams. There was also a three-fold decreasein mRNA encoding SNAT4, an amino...
The secret lives of African forest elephants: using genetics, networks, and telemetry to understand sociality
(University of Missouri--Columbia, 2012)
Knowledge of social structure is important to understanding the overall evolution and behavioral ecology of a species as it ultimately influences spatial patterns and gene flow. This dissertation focuses on the social structure of African forest...
The genetic and physiological basis of total energy budget in different nutritional environments
(University of Missouri--Columbia, 2020)
Organisms need to adapt to dynamic environments over time. An organism consumes and stores a finite amount of resources that are used for all daily tasks. In order to survive and thrive, they must allocate these finite ...
The Agrobacterium tumefaciens min system contributes to the regulation of cell division
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] In A. tumefaciens, the essential FtsZ protein is located at the growth pole before shifting to the mid-cell right before division. Recruitment of FtsZ to mid-cell is required...
Effects of prescribed fire and timber harvest on terrestrial salamander abundance, behavior, and microhabitat use
(University of Missouri--Columbia, 2014)
The goal of my dissertation was to assess how terrestrial salamanders respond to two common forest management practices -- prescribed fire and timber harvest. Previous studies have reported that timber harvest adversely affects terrestrial...
Conservation genetics of conflict in the Asian elephant, Elephas maximus
(University of Missouri--Columbia, 2021)
and elephants, research increasingly relies on noninvasive monitoring combined with a diverse assemblage of genetic tools. This dissertation uses conservation genetics to evaluate major conflict and conservation issues for Asian elephants. The first study...
Impact of selective motor neuron death on hypoglossal motor neuron survival and tongue morphology in a novel model of dysphagia
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Amyotrophic lateral sclerosis (ALS) is a devastating disease characterized by the progressive loss of motor neurons and paralysis of the muscles they innervate. Hypoglossal...
Genome-wide exploration of direct GBX2 target genes and their contributions to mouse development
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The cells that comprise the vertebrate nervous system require molecular cues to determine their cellular position, identity and their ability to make appropriate connections...
Characterizing a model of early human placenta
(University of Missouri--Columbia, 2020)
been learned about the structures of the embryo formed during this time, but any experimentation to determine function is impossible. This is not only due to ethical restrictions but also due to the fact that women are unaware of when implantation...
Low-level laser therapy for the treatment of osteoarthritis in the dog
(University of Missouri--Columbia, 2020)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] In veterinary medicine there is increasing interest in the use of low-level laser therapy (LLLT) for the treatment of pain in dogs with OA. Recently, a study found...