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NIR fluorescent sensors for blood pH and fructose
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Blood serum parameters are tightly associated with human beings' physiological activities, therefore the real-time monitoring of blood serum parameters attacks great attention...
Modeling EAA requirement and developing low fishmeal diet for yellow perch
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Overall, my dissertation research sought to enhance production of yellow perch by developing a low cost, complete diet for juvenile yellow perch by determining: the digestibility...
The inhibition of cysteine peptidases improves in vitro maturation of porcine cumulus-oocyte-complexes
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The cell permeable cysteine peptidase inhibitor, E-64, has shown utility as a potent and irreversible inhibitor for many cysteine proteases. Consequently, it has been studied...
Analysis of Gbx genes during neural development
(University of Missouri--Columbia, 2013)
). Furthermore there is an abnormal clustering of nV cell bodies arising from r2 and r3. These phenotypes can be rescued by injecting mouse Gbx2 mRNA (Buckley et al., 2013). This dissertation provides the first functional analysis of Gbx1 during mouse embryonic...
Stem cells and DNA methylation reprogramming in pigs
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] In mammals, the majority of cells in the body contain the same genome as other cells. The concept of nuclear totipotency has been well demonstrated by cloning animals generated...
Generation and characteriazation of porcine induced trophoblast
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Trophoblast stem cells are progenitors of all trophoblast lineages that compose fetal placental portion. Trophoblast stem cells provide an unlimited source of immature...
Effect of endophyte-infected tall fescue on hepatic gene expression in cattle
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Fescue toxicosis may result from the intake of ergot alkaloids found in endophyteinfected (E+) tall fescue. The liver if the major organ involved in the pathology of fescue...
Use of simvastatin to inhibit advanced prostate cancer formation in the TRAMP mouse model of prostate cancer
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] A provocative question currently proposed by the NIH is: do statin medications, which lower serum cholesterol, prevent cancer? We hypothesize that statins work by lowering...
Urocortin as a measure of stress in livestock
(University of Missouri--Columbia, 2012)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Stress is a fact of life for every living thing. In livestock species, stress can affect an animal's performance, thus leading to decreased profit for producers. For decades...
Development of a pregnancy associated glycoprotein assay to detect late embryonic mortality in cattle
(University of Missouri--Columbia, 2015)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Embryonic mortality (EM) decreases profitability of a beef or dairy operation because of the impact that it is has on delaying the time of conception and consequently calving...
Abundance of TRIM28, SETDB1, and TP53 mRNA is dynamically regulated during porcine early embryogenesis and is abnormal in preimplantation embryos produced by in vitro fertilization in comparison to in vivo derived and nuclear transfer derived embryos
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] In vitro embryo production is important for research in animal reproduction, embryo transfer, transgenics, and cloning. However, in vitro-derived embryos generally have delayed...
Developmental exposure to bisphenol a (BPA) and ethinyl estradiol (EE) and effects on F1 parental care and F2 pup parameters in California mice (Peromyscus californicus)
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Environmental exposure during the perinatal period can promote health and disease in offspring, otherwise coined developmental origins of health and disease (DOHaD). Endocrine...
The role of the mammary gland during heat stress
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Disruptive effects of climate change, such as increasing environmental temperature, have direct impacts on economic viability and efficiency of food production. In lactating...
Effects of conjugated linoleic acid on tissue lipid composition and bone remodeling in an ovariectomized aged rat model
(University of Missouri--Columbia, 2012)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Dietary fat is known to alter certain characteristics of bone metabolism in rats. CLA has been shown to decrease arachidonic acid and PGE2, thus improving bone density...
Determination of allelic expression of H19 in pre- and peri-implantation mouse embryos
(University of Missouri--Columbia, 2013)
H19 is a maternally-expressed imprinted non-coding RNA with tumor suppressor activity. H19 is located in an imprinted cluster which contains the paternally-expressed fetal growth factor Igf2. Monoallelic expression of H19 ...
Effects of heat stress on leukocyte function and gene expression in lactating dairy cows
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The effects of heat stress in animal agriculture are expected to become more serious as global temperatures continue to increase. Negative effects on production, reproduction...
Improving viability of immunodeficient RAG2-/- pigs by non-specific porcine antibody administration
(University of Missouri--Columbia, 2020)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Immunodeficient swine models such as the RAG2-/- model, are valuable to the field of regenerative medicine; however, their utility would greatly benefit from increased longevity...
Altered microrna expression profiles in bovine fetuses with an assisted reproduction-induced congenital overgrowth syndrome
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Assisted reproductive technologies (ART) refer to a series of fertility treatments used to conceive offspring. ART is used worldwide in humans for treatment of infertility...
The effect of reduced nocturnal temperatures on the performance of broiler chicks and hen turkey poults from 0 to 21 days of age
(University of Missouri--Columbia, 2018)
is the method of reduced nocturnal temperatures. Johnston and coworkers (2013) studied this 4 management strategy in an effort to determine if it would be a viable option in reducing energy usage without affecting pig performance and therefore, making operations...
Zinc ion fluxes on the pathway to mammalian sperm fertilization competency
(University of Missouri--Columbia, 2019)
For decades, the role of the divalent ion calcium was the focus of understanding mechanisms leading to sperm fertilization competency and management of semen storage. Little focus has been placed on other divalent ions, ...