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Drug resistance in D. discoideum: isolation of 4-nitroquinoline 1-oxide resistant mutants
(University of Missouri--Columbia, 2005)
The drug 4-nitroquinoline 1-oxide (4NQO) displays both carcinogenic and antitumor effects, a well known characteristic of many chemotherapeutic drugs. In addition 4NQO shares a similar operating mechanism with the commonly used chemotherapeutic drug...
Behavioral choice and demographic consequences of wood frog habitat selection in response to land use
(University of Missouri--Columbia, 2007)
throughout the circular experimental timber harvest arrays (164 m radius) by using standard radiotelemetry techniques. Prior to timber harvest, I found that wood frogs were not distributed equally throughout oak-hickory forest. Adults used drainages as non...
Identification and characterization of M cells in the mammalian conjunctiva
(University of Missouri--Columbia, 2007)
The M cell is a morphologically and functionally distinct epithelial cell found in the follicle associated epithelium (FAE) above organized lymphoid tissue at distinct locations along mucosal surfaces. By sampling antigens ...
Regulation of ceramide synthase 1 in cellular stress response
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Ceramides are intimately involved in a wide range of cellular processes. In mammals, de novo ceramide synthesis is catalyzed by the 6 ceramide synthase ...
The role of terrrestrial habitat in the population dynamics and conservation of pond-breeding amphibians
(University of Missouri--Columbia, 2007)
I used both demographic modeling and experimental field research to evaluate the role of terrestrial habitat in the population dynamics and conservation of pond-breeding amphibians. I began by using literature data to ...
Behavioral endocrinology of female gray treefrogs, Hyla versicolor, in response to acoustic stimulation
(University of Missouri--Columbia, 2008)
Particularly in organisms with a limited breeding period, females must rely on both external and physiological cues to regulate the phenology of reproduction and behavior. I investigated the relationship between male ...
A study of the role of the Atg8 protein in autophagic vesicle formation
(University of Missouri--Columbia, 2009)
) The deconjugation of Atg8 from PE is essential for completion of autophagosome formation (2) Deconjugation of Atg8-PE requires Atg4 protease; (3) presence of Atg18 protein is essential for deconjugation during starvation. Here we present substantial evidence...
Role of non-hypophototropic hypocotyl[3] (NPH[3]) in regulation of phototropism in Arabidopsis
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Light is arguably one of the most important environmental factor that not only provides the plant with its energy needs but also cues to modulate its ...