Search
Now showing items 1-20 of 594
Communities or Collections matching your query
Items matching your query
Orthopedic Tissue Engineering
(2010-03)
and biologists at KU, KUMC, UMKC, and beyond, and look forward to exploring further opportunities at the Missouri Regional Life Sciences Summit....
Creation of 'Super Avastin': A New Nanomedicine Approach for the Treatment of PXE and AMD [abstract]
(2010-02)
Nanomedicine is an emerging medical area that utilizes nanoparticles for the detection and treatment of diseases. The ubiquitous place of gold in Nanomedicine stems from its chemical ability to serve in an unoxidized state ...
Towards the Biological Synthesis of fullerene molecules [abstract]
(2010)
This invention describes the synthesis of carbon fullerene molecules and nanotubes using biological or enzymatic means. Presently carbon nanotubes are synthesized by either chemical vapor deposition or by electrical discharge ...
Nanostructures for Diagnostics and Delivery [abstract]
(2010)
Nanostructures are increasingly being recognized for their novel applications in biological systems including nanomedicine— the application of nanoscale technologies for diagnosis, treatment and prevention of diseases. ...
Creating a Health Care Business from University Research
(2010-03)
consortium is developing advanced bioactive glasses and investigating their use for repairing traumatized bone and tissue. The latter part of this presentation discusses entrepreneurship and the locations of creative activity (patents) in Missouri...
Of Mice and Men and the Search for an Alzheimer's Disease Treatment
(2010-03)
to solving the Alzheimer's disease problem. Clinical and basic science investigators with a wide range of backgrounds have dedicated themselves to this disease. This talk will review the current state of Alzheimer's disease research and discuss where we...
KU Center for Technology Commercialization: "promoting innovation to benefit society"
(2010-03)
The presentation will examine the challenges of the university technology transfer office in assessing new invention disclosures and the various means of doing so. The presentation will also provide information on different ...
Tao3 mediates a phenotypic switch between amoeba-adapted and mammalian-adapted forms of Cryptococcus neoformans
(2010-03)
Many microbes are capable of changing phenotypes more frequently than due to basal mutation rates alone, and this ability is coupled to pathogenesis. The human pathogenic yeast Cryptococcus neoformans is found in the ...
Engineering Optimal Islets for Transplantation for Type 1 Diabetes [abstract]
(2010-03)
Islet transplantation offers an improvement in the quality of life for those suffering from type 1 diabetes. It is found that islet cells may die during or soon after transplantation. Studies in our lab have shown that small islets are superior...
UMKC Center of Excellence in the Study of Dental and Musculoskeletal Tissues (CEMT) [abstract]
(2010-03)
, Medicine, Nursing, Biological Sciences, and Computing and Engineering that focus on dental and musculoskeletal health. The Center of Excellence integrates basic and clinical investigators into a powerful translational team to prevent and treat diseases...
Quantitative Profiling of S-Nitrosylated Proteins in Parkinson's Disease Paradigms for the Effects of Botanical Phenolics [abstract]
(2010-02)
A convergent feature for most aging-related neurological diseases, such as Parkinson's Disease (PD), is excessive generation of free radicals - reactive nitrogen and oxygen species, which can contribute to neuronal cell ...
Use of Aggregation Prediction in Protein Formulations for Excipient Design
(2010-03)
immune responses in patients. Excipients are additive molecules that are not therapeutically active, but can increase the stability of protein formulations. An ideal excipient binds with aggregation prone regions on the protein to limit interaction...
Dangerous Drug Reactions on the S&A iPhone App [abstract]
(2010)
The S&A drug database for handhelds, sold to dermatologists for 8 years, was uploaded as a new iPhone application (app), February 2010. Our program notes all warnings at the several FDA levels: boxed warnings, bold warnings, warnings, and adverse...
Dose escalation safety study of Nanotax® in dogs [abstract]
(2010)
circulation. The circulating half life is short which may be a result of clearance by the reticuloendothelial system. Final postmortem evaluation will be performed to determine whether the drug has accumulated in any organ system. We will use data generated...
Mechanism-based Inhibitor of Matrix Metalloproteinase-9 Rescues Brain from Focal Cerebral Ischemia-induced Damage and Improve Neurological Outcomes in Mice [abstract]
(2010-02)
Stroke is the third leading cause of death in the US and the primary cause of long-term disability. Acute ischemic stroke, the most common form of stroke, is caused by clotting in the cerebral arteries leading to brain ...
A Novel Method to Monitor Sequential Displacement of Capped Ligands in Gold Nanoparticles [abstract]
(2010-02)
Nanochemistry of ligand displacement reactions has attracted much attention in recent years for the development of myriad of new gold nanomaterials. Gold nanoparticles have shown applications ranging from tumor imaging ...
A Comparative Study between Antibody and Peptide Conjugated Gold Nanoparticles for In Vivo Targeting of EGFR in Pancreatic Cancer Bearing Mice Models [abstract]
(2010-03)
Pancreatic cancer is the fourth leading cause of cancer related deaths in the United States due to its severe aggressiveness and lethal malignancy. Epidermal Growth Factor Receptor (EGFR) is over expressed in more than 95% ...
Clinical Translation of Nanopharmaceuticals for Cancer Therapy [abstract]
(2010-02)
The most recent study involving 77,000 North American men has shown that regular prostate specific antigen (PSA) screening did not provide accurate diagnosis of prostate cancer and therefore did not save lives of cancer ...
Cytotoxic Oleanane-type Triterpenen Saponins with N-acetyl Sugar from Albizia inundata [abstract]
(2010)
Bioassay-guided fractionation of a CH2Cl2-MeOH extract of the aerial part of Albizia inundata , collected in Argentina, resulted in the isolation of two new oleanane-type triterpene saponins with N-acetyl sugar (1, 2) and ...