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Tao3 mediates a phenotypic switch between amoeba-adapted and mammalian-adapted forms of Cryptococcus neoformans
(2010-03)
Many microbes are capable of changing phenotypes more frequently than due to basal mutation rates alone, and this ability is coupled to pathogenesis. The human pathogenic yeast Cryptococcus neoformans is found in the ...
The Vision Research Center of Kansas City
(2010-03)
The Vision Research Center was founded as and is a well established collaboration of several of UMKC schools and Kansas City Medical Centers and thus offers an unprecedented interdisciplinary synergy with a unified goal: ...
Public-Private Collaborations to Promote Adult Literacy
(2010-03)
. Adapting educational materials is an appropriate short-term intervention. But these women wanted and needed much more. Low literacy negatively impacts the quality of an individual's entire life, not just health. Examples of life tasks requiring literacy...
Cofactor Genomics: A Sequencing Service Company Emerges from the Technology Development Laboratory
(2010-03)
, evaluate and develop both wet-lab and computational applications for emerging Next-Generation sequencing technology platforms. Their experience began with beta testing the 454 Life Sciences (now Roche) GS 20, continued with beta testing the first serial...
Transgenic and Gene-Targeting Facility
(2010-03)
The Transgenic and Gene-Targeting Facility at the University of Kansas Medical Center is located in the newly constructed Kansas Life Sciences Innovation Center on the KUMC campus. The mission of the Transgenic Facility is to provide services...
A genetic linkage map of the fungus Phycomyces blakesleeanus
(2010-03)
of point mutations in furA and lysA genes that flank madD and madE, respectively. Additionally, using the carRA and carB genes as a starting point, the DNA regions near the madI gene have been found and the adjacent carS gene identified....
An Intelligent Online System for Enhanced Recruitment of Patients for Clinical Research
(2010-03)
The recruitment and retention of subjects for clinical research has been identified as one of the bottlenecks in the development of new drugs and treatments by the healthcare industry. The Kansas City Area Life Sciences Institute has been...
Are there leaks in your product pipeline?
(2010)
professional statistician. The University of Missouri System has statisticians on several campuses. There are graduate programs at the University of Missouri, UMKC and Missouri University of Science and Technology. Graduate students are available...
Do Patients with Craniosynostosis Have an Increased Incidence of Auditory Neuropathy as Newborns?
(2010-02)
screening and, if patients were referred, diagnosis from audiologic diagnostic testing were obtained from the Missouri Department of Health. Institutional review board approval was obtained. PATIENTS: One hundred and thirty-five patients were identified...
Skin Scan Digital Dermoscopy Skin Cancer Training Software
(2010-03)
Skin Scan digital dermoscopy skin cancer detection software, developed by Rolla's S&A in collaboration with Missouri S&T, can now detect critical features of early melanoma. There is also a need for diagnostic help for the other 95+% of skin...
Effect of Radius on Load Distribution within Mouse Forearm Structure: Experimental and Numerical Analyses
(2010-03)
It has been hypothesized that osteocytes are stimulated by local strain distribution within the bone subjected to mechanical loadings. This collaborative research project between bone biologists and mechanical engineers ...
A Study of RO5217790 (HPV Targeted Immunotherapy) in Patients With High Grade Cervical Intraepithelial Neoplasia Associated With High Risk HPV Infection
(2010-03)
This is a randomized, double blind, placebo controlled, parallel group multicenter study in women with biopsy confirmed Grade 2 or Grade 3 cervical intraepithelial neoplasia (CIN). Two hundred patients will be enrolled and ...
Neutersol® from Laboratory to Market--Lessons Learned
(2010-02)
was done at the University of Missouri-Columbia and was sponsored by a small business venture capital company. The Neutersol® experience with the following questions offers lessons that are applicable to R&D of most male contraceptive medicines and devices...
The Antigen Display on Bacillus Endospore (ADOBE) System a Noninvasive Biodegradable Microparticle Display System
(2010)
The development of safe and effective vaccines and adjuvants remains an important global public health goal. The Antigen Display on Bacillus Endospore (ADOBE) system, developed at the University of Missouri's College of Veterinary Medicine, is a...
Development of a Telemetry Unit for Wireless Monitoring of Bone Strain
(2010-03)
A telemetry unit designed to monitor strain in bones is presented. This unit allows studying the relationship between bone load and bone mass in scenarios that were not possible with current setup. The current measuring ...
The Fungal Genetics Stock Center at UMKC is an International Biological Resource Center
(2010-03)
Founded in 1960, the Fungal Genetics Stock Center enters it's fiftieth year of operation during a period of tremendous growth. The collection has more than doubled since moving to UMKC in 2004 and has added new materials ...
Guided-mode resonance biochip system for early detection of ovarian cancer
(2010-03)
A high-accuracy, sensor system has been developed that provides near-instantaneous detection of biomarker proteins as indicators of ovarian serous papillary carcinoma. Based upon photonic guided-mode resonance technology, ...
Turbo Mohs for Basal Cell Carcinoma Skin Cancer
(2010-03)
Mohs skin cancer surgery is also known as microscopically-controlled surgery because at each stage in the Mohs procedure, a new layer of tissue is obtained surgically and frozen sections made, allowing a microscopic reading ...
Toxicty of a Serotonin-derived Neuromelanin
(2010)
Introduction: POCD (Postoperative Cognitive Dysfunction) is associated with increased mortality and disability and may develop as a consequence of lipid peroxidative byproducts (i.e. acrolein), which accumulate with aging. ...
Shelter Dog Behavior Improvement: Dog Walking as Enrichment
(2010)
Background: Several million dogs are euthanized in animal shelters annually after multiple relinquishment reasons (Scarlett, 2002; Salman, 1998; New, 2000 & Kass, 2001). Gains in pet adoptions are happening via shelter ...