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Aspirin Use in Children for Fever or Viral Syndromes
(Family Physicians Inquiries Network, 2009)
Aspirin should not be used to treat acute febrile viral illness in children. (Strength of Recommendation [SOR]: C, based on case- control studies). Although no causal link has been proven, data from case-control and historic ...
What does the evidence tell us about treating very-high-risk patients to an LDL <70 mg/dL?
(Family Physicians Inquiries Network, 2009)
No studies directly compare low-density lipoprotein (LDL) levels <70 mg/dL to levels of 71 to 100 mg/dL in very-high-risk patients. However, no evidence suggests a "floor" for LDL cholesterol levels beyond which further ...
What's the best way to monitor low-risk patients with a history of differentiated thyroid cancer?
(Family Physicians Inquiries Network, 2009)
Recombinant human thyrotropin (rhTSH)-stimulated serum thyroglobulin (Tg) level alone is sufficient to monitor for recurrent disease in low-risk patients with a history of differentiated thyroid cancer (DTC) (strength of ...
Which strategies work best to prevent obesity in adults?
(Family Physicians Inquiries Network, 2009)
Regular physical activity decreases long-term weight gain (strength of recommendation [SOR]: B, 2 high-quality, randomized controlled trials [RCTs]). Decreasing fat intake (SOR: B, 1 high-quality systematic review) and ...
Pharmacologic therapy for eustachian tube dysfunction
(Family Physicians Inquiries Network, 2013)
There are no medications that improve patient-oriented outcomes in children or adults with eustachian tube dysfunction. (Strength of Recommendation [SOR]: A, based on a systematic review of randomized controlled trials ...
Let them eat nuts -- this snack is safe for diverticulosis patients
(Family Physicians Inquiries Network, 2009)
Tell patients with diverticular disease that they can eat nuts, corn, and popcorn without fear. There is no truth to the long-held belief that these foods increase the risk of complications. Strength of recommendatin: B: ...
Antidepressant Medications in Pregnancy
(Family Physicians Inquiries Network, 2004)
Selective serotonin reuptake inhibitors (SSRIs) are considered first-line agents for the treatment of depression in pregnant women. SSRIs and tricyclic antidepressants (TCAs) are considered safe and effective in pregnant ...
What is the best approach to prevention and treatment of osteoporosis?
(Family Physicians Inquiries Network, 2001)
Randomized controlled trials (RCTs) have demonstrated decreased vertebral and nonvertebral fracture rates in postmenopausal osteoporotic women taking a bisphosphonate (alendronate or risedronate). Hormone replacement therapy ...
How should you evaluate an asymptomatic patient with a femoral or iliac artery bruit?
(Family Physicians Inquiries Network, 2009)
Perform an ankle-arm index (AAI, or ankle- brachial index) test to evaluate for peripheral artery disease (PAD) (strength of recommendation [SOR]: B, cohort studies). If the test detects PAD, recommend steps to modify ...
Offer this contraceptive to breastfeeding new moms
(Family Physicians Inquiries Network, 2011)
Recommend the etonogestrel implant to new mothers who plan to breastfeed; the insertion of this contraceptive within the first few days postpartum does not alter breastfeeding outcomes. Stength of recommendation: B: Based ...
What is the risk of bowel strangulation in an adult with an untreated inguinal hernia?
(Family Physicians Inquiries Network, 2007)
after potential strangulation. These risk factors include advanced age, limited access to emergency care, significant concomitant illness, inability to recognize symptoms of bowel incarceration, and poor operative risk (American Society...
ACE inhibitors and ARBs: One or the other -- not both -- for high-risk patients
(Family Physicians Inquiries Network, 2009)
Avoid prescribing an angiotensin-converting enzyme (ACE) inhibitor and an angiotensin receptor blocker (ARB) for patients at high risk of vascular events or renal dysfunction. The combination does not reduce poor outcomes, ...
What vitamins and minerals should be given to breastfed and bottle-fed infants?
(Family Physicians Inquiries Network, 2005)
supplementation for all term, healthy, breastfed infants is not proven to be safe or necessary. Formula-fed infants should be consuming formula that contains 10 to 12 mg/L of iron (SOR: A,
2 small randomized controlled trials)....
What blood tests help diagnose celiac disease?
(Family Physicians Inquiries Network, 2006)
Histological confirmation of infiltrative lesions via small bowel biopsy is the gold standard for diagnosing celiac disease. Four serum antibody assays may serve as a first- step diagnostic tool to identify biopsy candidates: ...
When should you order a Lyme titer?
(Family Physicians Inquiries Network, 2005)
Lyme titers should be ordered for patients with signs or symptoms of disseminated Lyme disease, but who do not have the pathognomonic erythema migrans rash (strength of recommendation [SOR]: C, based on expert opinion). ...
Should we screen for ovarian cancer?
(Family Physicians Inquiries Network, 2003)
Ovarian cancer screening using pelvic examination, CA-125 serum tumor marker, transvaginal ultrasound (TVU), or any combination of tests is not recommended in average-risk women, or in women with only 1 first-degree relative ...
Do statins cause myopathy?
(Family Physicians Inquiries Network, 2003)
If statins (HMG-CoA reductase inhibitors) cause myopathy, the risk is very low (strength of recommendation [SOR]: A). There is no direct evidence to answer this question. A pooled analysis of randomized controlled trials ...
What is the best way to manage phantom limb pain?
(Family Physicians Inquiries Network, 2009)
No single best therapy for phantom limb pain (PLP) exists. Treatment requires a co- ordinated application of conservative, pharmacologic, and adjuvant therapies. Evaluative management (including prosthesis adjustment, ...
Polypharmacy in the elderly
(Family Physicians Inquiries Network, 2009)
This issue of eMedRef provides information to clinicians on the pathophysiology, diagnosis, and therapeutics of polypharmacy in the elderly.
Does case management improve diabetes outcomes?
(Family Physicians Inquiries Network, 2008)
Patients with type 2 diabetes benefit from case management, as evidenced by decreased glycated hemoglobin (HbA1c). The improvement in HbA1c appeared larger when case managers could make changes in medications independently ...