Search
Now showing items 1-4 of 4
Discovery of PSMA-Specific Peptide Ligands and Development of A Noncovalent Method to Attach Chemical Moieties to siRNA
(University of Missouri -- Kansas City, 2017)
The objective of this dissertation is to discover PSMA (Prostate Specific Membrane
Antigen)-specific peptide ligands using phage display and employ peptide nucleic acid as
a complementary linker to attach chemical ...
Engineering of Human Acid Phosphatase Enzyme Sensitive Nanomedicine for HIV/AIDS Prevention by Topical Route
(University of Missouri -- Kansas City, 2018)
This study is divided into two aims. Aim #1 focuses on the development and
characterization of tenofovir (TFV) loaded a stimuli sensitive nanomedicine against male to
female HIV/AIDS infection. Aim #2 focus on the ...
Clear, Aqueous Topical Nanomicelle Formulation For Diabetic Macula Edema
(University of Missouri -- Kansas City, 2018)
The objective of this study was to develop a clear aqueous mixed nanomicellar
formulation (NMF) of hydrophobic drugs for diabetic macula edema. The hydrophobic
drugs include triamcinolone acetonide (TA), fluocinolonce ...
Novel Prodrugs and Self-Assembling Nanocarriers to Improve Drug Delivery
(University of Missouri -- Kansas City, 2018)
PART I: DIPEPTIDE PRODRUG APPROACH TO IMPROVE INTESTINAL
ABSORPTION OF LOPINAVIR
Lopinavir (LPV), a highly potent second-generation HIV-1 protease inhibitor, is
currently indicated in HIV-1 infection. However, poor ...