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Gene therapy in spinal muscular atrophy : RNA-based strategies to modulate the pre-mRNA splicing of survival motor neuron
(University of Missouri--Columbia, 2008)
Gene expression is the required process in eukaryotes in which DNA is transcribed into pre-mRNA, spliced to produce "mature" mRNA and translated into proteins. Inaccuracies in splicing events are receiving more attention ...
Gene expression profiling of bovine ovarian follicular selection
(University of Missouri--Columbia, 2006)
Lack of, or abnormal, ovarian follicular development is a major factor associated with impaired fertility in mammals. However, development of new treatments is limited by our poor understanding of ovarian follicular ...
Statistical analysis of multivariate interval-censored failure time data
(University of Missouri--Columbia, 2007)
A voluminous literature on right-censored failure time data has been developed in the past 30 years. Due to advances in biomedical research, interval censoring has become increasingly common in medical follow-up studies. ...
Racial differences in households' financial asset allocation, 1992-2004
(University of Missouri--Columbia, 2007)
By combining the data from the 1992, 1995, 1998, 2001 and 2004 Survey of Consumer Finances, this study investigated racial differences in households' financial asset allocation over the years. This study categorized the financial assets into four...
Relation of Missouri river flows to sandbar morphology with implications for selected biota
(University of Missouri--Columbia, 2006)
Channel modification and flow regulation in historically braided large rivers, have reduced sandbars and associated highly productive habitats for riverine biota. Sandbars are an important interface between aquatic and ...
GABP regulation of the murine GABPa/ATPsynthase coupling factor six and human glutathione reductase promoters
(University of Missouri--Columbia, 2005)
GABPa is expressed from a bi-directional promoter expressing ATP synthase coupling factor six (CF6) in the opposite direction. This bi-directional promoter is regulated by GABP, indicating an autoregulation of GABPa. GABP is a redox sensitive...
Daily alcohol use and relationship functioning in young adult romantic relationships
(University of Missouri--Columbia, 2008)
of bi-directional influences between relationship functioning and alcohol use. The present study sought to address these limitations by examining bi-directional effects of alcohol use and relationship processes in a normal population sample of 81 couples...
Metamorphism of the Wales Group and Moira Group on Prince of Wales and Dall Islands, southeastern Alaska
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] This study examines the metamorphic history of the Proterozoic to Early Ordovician Wales Group and the newly-named Ordovician to Silurian Moira Group ...
Understanding students' technology appropriation and learning perceptions in online learning environments
(University of Missouri--Columbia, 2005)
Distance education has the unique characteristic of using technologies as the primary means of delivery of instruction and interaction. The present study contributes to research dedicated to explaining or predicting phenomena ...
Analysis and modeling of direct selective laser sintering of two-component metal powders
(University of Missouri--Columbia, 2005)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Direct Selective Laser Sintering (SLS) is an emerging technology of Solid Freeform Fabrication (SFF) that 3-D parts are built from the metal-based ...
Development of tailored preform processing technology for net-shape manufacturing of large monolithic structures
(University of Missouri--Columbia, 2007)
The aim of the present research effort involves exploration of a new processing approach, "Tailored Preform Processing (TPP)" technology for net-shape manufacturing of monolithic structures for the transportation industry. ...
Examination of metabolic and regulatory networks of desulfovibrio species
(University of Missouri--Columbia, 2004)
The sulfate-reducing bacteria are a morphologically diverse group of organisms characterized by the ability to couple the enzymatic reduction of sulfate to energy production and growth. This metabolic activity has profound ...
Prospective radiolabled bombesin conjugates for prostate cancer imaging and therapeutic agents
(University of Missouri--Columbia, 2009)
-99m ([superscript 99][superscript-m]Tc), Copper-64 ([superscript 64 ]Cu) or Bismuth-213 ([superscript 213]Bi)....
Three essays on entrepreneurship : theory, measurement, and environment
(University of Missouri--Columbia, 2007)
This dissertation consists of three essays. In Essay One, I question the conventional wisdom that economic transactions are governed either by the price mechanism or by the authority of the firm. I argue that the exchange ...
The effects of axotomy on the biophysical properties of reticulospinal neurons in larval lamprey
(University of Missouri--Columbia, 2006)
Following severe spinal cord injury (SCI), in adult higher vertebrates there is little or no axonal regeneration, and animals remain paralyzed below the lesion. In contrast, lower vertebrates such as the lamprey, following ...
Fluorescence spectroscopy and parallel factor analysis of waters from municipal waste sources
(University of Missouri--Columbia, 2007)
location. Parallel Factor Analysis (PARAFAC) has recently been used to effectively model EEM data sets. This thesis continues the study of the EEM/PARAFAC technique by applying it to waters of municipal waste sources. Bi-weekly samples were collected over a...
Nitrification enhancement in lagoons using fixed film media
(University of Missouri--Columbia, 2007)
involved conducting performance study of the Kingdom City lagoon, and evaluating the effect of the fixed film technology on the performance of the lagoon to remove pollutants of concern. Bi-weekly wastewater samples were collected during September 2005...
Functional outcome and self-perceived overall health status following surgery to remove primary brain tumor
(University of Missouri--Columbia, 2008)
=0.05; Tinetti: df=1, F=7.2, p=0.03) and from immediately post-surgery to 3 months post-surgery, ( SF-36: df=1, F=14.8, p=0.006; TUG: df=1, F=24.3, p=0.003; Tinetti: df=1, F=39.0, p<0.001). From pre-surgery to 3 months post-surgery, no significant...
Communicating medical advances in television health news : the influence of a human interest frame on audiences' cognitive and emotional responses
(University of Missouri--Columbia, 2010)
The dissemination of scientific advances in medicine became popular in television health news over the last few decades. The purpose of this study is to investigate the influence of news frames in television health news ...
Development and validation of a computational multibody model of the elbow joint
(2014-03-25)
Computational multibody models of the elbow joint can provide a powerful tool to study joint biomechanics, examine muscle and ligament function, soft tissue loading, and the effects of joint trauma. Such models can reduce ...