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Development of a fluorescence-based protease biosensor using nanoscale platforms
(University of Missouri--Columbia, 2010)
The development of a protease biosensor utilizing nanomaterials is presented in this dissertation. Peptide substrates and nanomaterial platforms were investigated to increase the sensitivity and response time for the detection of protease analytes...
Self-aligned microchip device for automated measurement of quantal exocytosis
(University of Missouri--Columbia, 2010)
Here we describe a method to fabricate a multi-channel high-throughput microchip device for measurement of quantal transmitter release from individual cells. Instead of bringing carbon-fiber electrodes to cells, the device ...
Quantification of cell attachment on different materials as candidate electrodes for measurement of quantal exocytosis
(University of Missouri--Columbia, 2008)
A high throughput lab-on-a-chip device is being developed for single cell capture for the purpose of high time resolution quantal exocytosis measurement with high probability of cell docking. This device makes use of DLC ...
A novel PCR based DNA microanalyzer system for detection of viral genome
(University of Missouri--Columbia, 2006)
code. The micro-pumps, PCR chamber and capillary electrophoresis system have been designed fabricated and tested. For fabrication of the device, a regime has been developed for bonding PDMS surfaces to a variety of substrates (silicon in the present...
Synthesis and characterization of nanostructures and their applications : from supercapacitors to fluorescent labels to proteins
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Nanomaterials have gained importance in virtually all fields from industrial applications to pure science research since these were developed. However, ...
Characterization and MEMS applications of nanothermite materials
(University of Missouri--Columbia, 2010)
The research described herein is on characterization of nanothermite materials and development of nanothermite microdevices for shock wave generation, microthruster propulsion, and intracellular particle delivery and cell ...
Single molecule imaging of DNA on nanogap embedded plasmonic gratings with enhanced fluorescence and improved level of detection
(University of Missouri--Columbia, 2020)
low quantities of biomolecules tagged with fluorophores. In this thesis, a cheap and simple fabrication technique is presented for producing polymethylsilsesquioxane (PMSSQ) based gratings embedded with nano-gaps using micro-contact printing where a...
Development of a human immunodeficiency virus (HIV-1) biosensor utilizing liquid core waveguides
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Millions of individuals are diagnosed each year with Human Immunodeficiency Virus Type 1. Each day more individuals are receiving antiretroviral ...