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From developmental biology to tissue-engineering: printing blood vessels
(University of Missouri--Columbia, 2009)
-engineering, evidenced by the fact that they can elicit adverse host responses and interfere with, rather than guide, direct cellcell interaction as well as assembly and alignment of cell-produced extracellular matrix. Understanding the physical principles of biological...
Theoretical and in silico modeling of biological systems : from protein structure prediction to cellular dynamics
(University of Missouri--Columbia, 2009)
This thesis describes four distinct studies (involving a variety of concepts and methods from the physical sciences) of complex biological systems and processes that cover a wide range of time and length scales (extending from the molecular...
Genome evolution in monocots
(University of Missouri--Columbia, 2011)
Monocotyledonous plants are a well-circumscribed lineage comprising 25% of all angiosperm species, including many agriculturally and ecologically important species (e.g., grasses, palms, orchids, lilies, yams, pondweeds, ...
SIRT1 deacetylation regulates NFAT transcriptional activity
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The class III histone deacetylase SIRT1 plays important roles in aging, metabolism and biological clock control. We have recently demonstrated that SIRT1 is a critical factor...
An investigation of maize B chromosome-derived minichromosomes
(University of Missouri--Columbia, 2012)
The maize (Zea mays) B chromosome is a supernumerary chromosome with a selfish inheritance characterized by nondisjunction at the second pollen mitosis, univalent survival in meiosis, and preferential fertilization of the ...
The developmental liver transcriptome of Rattus norvegicus
(University of Missouri--Columbia, 2012)
less well understood. In an attempt to investigate this area of research, we developed a time course experiment including both pre- and postnatal liver samples whereby RNA sequencing was performed on each of the biological stages. We investigated...
Phylogenetic and behavioral differentiation in the canyon treefrog, Hyla arenicolor
(University of Missouri--Columbia, 2011)
intraspecific phylogenies using both sequence data and AFLP markers. I describe biologically significant differences in call properties among the geographically distant Mexican lineages relative to differences found among the USA populations. Results from female...
Examining beginning biology teachers' knowledge, beliefs, and practice for teaching natural selection
(University of Missouri--Columbia, 2012)
goals: 1) Develop content knowledge of evolution; 2) Accept evolution as scientifically valid; 3) Develop understandings of the nature of science related to evolution; 4) Develop strategies for handling the public controversy; and 5) Develop pedagogical...
Potential benefits of social media in a weapons of mass destruction (WMD) event
(University of Missouri--Columbia, 2011)
an improbability, and life sciences can be easily manipulated to produce a biological WMD. If a biological WMD is unleashed, strategic communications will be a critical facet for its management. In mass casualty situations, the medium of social media and social...
Hellbender (Cryptobranchus alleganiensis) gene flow within rivers of the Missouri Ozark highlands
(University of Missouri--Columbia, 2013)
For species of conservation concern, effective management includes maintaining robust population sizes while monitoring and promoting genetic variability. For hellbenders (Cryptobranchus alleganiensis), an aquatic salamander ...
Biology and control of Amur honeysuckle
(University of Missouri--Columbia, 2013)
the biology and control options for this plant. The objectives of this research were to: a) determine efficacy of various herbicides using postemergence and basal bark applications; b) determine the means of seed spread and time at which Amur honeysuckle seeds...
The effects of histone acetylation on the maize allele PL1-blotched
(University of Missouri--Columbia, 2007)
Covalent modifications of DNA and nucleosomal histone proteins associated with eukaryotic chromatin have the potential to alter expression of a gene without change in its DNA sequence. One gene regulated through this ...
Image and video analysis techniques for cellular microscopy
(University of Missouri--Columbia, 2014)
data into biological knowledge. Unique challenges posed by different imaging modalities and cell dynamics require a combination of accurate detection, segmentation, classification and tracking approaches tailored to address and exploit particular image...
The abundance and diversity of stream salamanders on montane golf courses
(University of Missouri--Columbia, 2012)
of their susceptibility to a range of environmental disturbances, it is widely believed that stream salamanders are useful as biological indicators of ecosystem health. The first study in this thesis examines how stream substrate complexity influences both capture rates...
Social and psychobiological regulation of the human child's hypothalamus-pituitary-axis : an ontogenetic perspective
(University of Missouri--Columbia, 2011)
and dehydroepiandrosterone (DHEA), seems to play a pivotal role mediating the relationships between the social environment and an individual's life history strategies. Yet the processes that underlie the biological embedding of social information remain unclear in humans...
A study of reproductive toxicology
(University of Missouri--Columbia, 2012)
studies report DEHP reduces fetal testosterone production at doses greatly exceeding human exposure. We fed pregnant CD-1 mice 0.5 - 500,000 [mu]g/kg/day DEHP from gestation day (GD) 9 - 18 and examined mothers and male fetuses on GD 18. We assessed non...
Fetal exposure to low but not high doses of Bisphenol A (BPA) increases abdominal fat, impairs glucose tolerance and alters serum hormones in male mice : evidence for non-monotonic dose-response relationships
(University of Missouri--Columbia, 2012)
range. We fed pregnant CD-1 mice BPA at doses ranging from 5-50,000 [mu]g/kg/day, spanning 10-fold below the reference dose to 10-fold above the no adverse effect level (NOAEL). At doses below the NOAEL we observed numerous significant effects in adult...
Genetic variation and population structure in the endangered Houston toad in contrast to its common sympatric relative, the coastal plain toad
(University of Missouri--Columbia, 2010)
the Austin County population, and involvement of the general public in conservation....
Ecological conditions of secondary sexual dimorphism in salix glauca : fundamental and realized dimorphic niche
(University of Missouri--Columbia, 2006)
This thesis explores the dimorphic niche of ecological conditions hypothesis as the selective force behind secondary sexual dimorphism in Salix glauca, a dioecious willow shrub. The dimorphic niche hypothesis predicts trait ...
Collective offspring-parent signaling in a social treehopper : mechanisms, patterns and function
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] I investigated the properties of collective behavior in a group-living insect, including the patterns of group behavior, the function of group level ...