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The phenomena of retraction in biomedical literature
(2010)
in the biomedical literature from 1966 to 1997 and found that “retracted articles continue to be cited as valid work…after publication of the retraction.” Originally presented at MOBIUS conference 2010....
Mining host-pathogen interaction from biomedical literature
(University of Missouri--Columbia, 2011)
against pathogenic organisms. Our understanding of the mechanisms can be greatly enhanced by the data at the molecular level, at which interactions between the host and pathogen proteins occur. While conducting experiments to verify a biomedical discovery...
Research in motion
(2010-03)
, and joint replacement, and on exploring tissue-engineered cartilage as a possible biological replacement of diseased and arthritic joints. An interdisciplinary team approach to these goals has resulted in peer-reviewed publications, graduate student...
Targeting the myofibroblast : new strategies in managing equine corneal fibrosis
(University of Missouri--Columbia, 2014)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Corneal disease is a common cause of blindness in horses as a result of various causes including traumatic, autoimmune, neoplastic, or infectious ...
The role of CFTR in regulating the cell cycle of intestinal stem cells
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] [Abstract taken from public pdf.] Cystic fibrosis (CF) patients and CF mouse models have an increased risk for gastrointestinal (GI) cancer. Intestinal stem cells (ISCs...
Role of the intermediate-conductance Ca²⁺-activated K⁺ channel (K[ca]3.1) in coronary smooth muscle cell phenotypic modulation
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Smooth muscle cell phenotypic modulation is characterized by suppression of smooth muscle specific marker gene expression, migration, and proliferation ...
Canine pharmacodynamic assays: applications in immune-mediated disease
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Immune-mediated diseases are commonly diagnosed in veterinary medicine and a high rate of mortality, expense and complications of immunosuppressive ...
Vascular maladaptations to chronic disease and physical inactivity
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Physical inactivity due to increases in modern conveniences and access to cheap, high calorie foods have greatly contributed to the "obesity epidemic" ...
Ethical Issues: Futility Policies
(Center for Health Ethics, 2005-03)
Futility, in general, is the inability to achieve an intended goal or outcome. Biomedical futility more specifically is a clinical judgment that, in light of the patient's current clinical circumstance, it is not physiologically possible...
Sympathetic control of the collateral circulation : effects of time post-occlusion and exercise training
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] These studies evaluated the role of alpha-adrenergic receptors ([alpha]AR) and NPYergic receptors in the collateral circulation following acute and ...
New strategies in canine corneal wound healing for the veterinary ophthalmic patient
(University of Missouri--Columbia, 2012)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Canine corneal fibrosis is a significant clinical problem in veterinary ophthalmology. Corneal wound healing following injury or infection often results ...
Molecular epidemiology of tick-borne Anaplasmataceae among client-owned dogs in Missouri
(University of Missouri--Columbia, 2012)
Several tick-borne agents of zoonotic ehrlichiosis or anaplasmosis are endemic to Missouri. Dogs are susceptible to the same infections and tick vectors, but their roles as models, sentinels or reservoirs are undefined. ...
Parenteral fish oil effects on plasma non-esterified fatty acids and systemic cytokine concentrations in dogs immediately following ovariohysterectomy
(University of Missouri--Columbia, 2012)
An extreme systemic inflammatory response may be observed in dogs that experience severe accidental trauma, such as being struck by a car. The inflammatory response may be so extreme that it complicates treatment and causes ...
Analysis of coffin and shoulder joint lameness with an inertial sensor-based system : impact versus pushoff
(University of Missouri--Columbia, 2012)
Reason for performing the study: An inertial sensor-based system (Lameness Locator[copyright] [LL]) can help veterinarians detect mild lameness. It would be beneficial if this tool could also be used to distinguish lamenesses ...
Apigenin : chemopreventive and chemotherapeutic potential for progestin-dependent breast cancer
(University of Missouri--Columbia, 2012)
Use of estrogen-progestin hormone replacement therapy (HRT) has been linked to increased risk of breast cancer, an effect that has been attributed to the progestin component. Commonly available antiprogestins are associated ...
Cytauxzoon felis : an emerging feline pathogen and potential therapy
(University of Missouri--Columbia, 2011)
Cytauxzoon felis is a pathogenic hemoprotozoal parasite of Felidae. We were able to document, via both piroplasm detection and PCR analysis, a chronic carrier state in naturally infected captive bred tigers as well as ...
The effects of furosemide on ureteral diameter and attenuation using computed tomographic excretory urography in normal healthy dogs
(University of Missouri--Columbia, 2012)
A number of imaging techniques have been employed to try and diagnose ureteral disease, including ectopic ureters. CTEU has overcome those disadvantages and has become the imaging modality of choice for evaluating human ...
The mechanism of C-type natriuretic peptide production in dogs and its use as a prognostic indicator in critically ill dogs
(University of Missouri--Columbia, 2012)
The N-terminal portion of pro C-type natriuretic peptide (NT-pCNP) has shown promise as a diagnostic biomarker for sepsis in humans and dogs. The mechanism of NT-pCNP induction and its use as a prognostic indicator in dogs ...
Acute and chronic adaptations to intermittent pnemuatic [sic] leg compressions
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Few therapies exist that improve functional capacity and quality of life of patients with peripheral arterial disease (PAD). Despite the growing ...
Double pelvic osteotomy for the treatment of hip dysplasia in dogs
(University of Missouri--Columbia, 2011)
Canine hip dysplasia (CHD) is the most common developmental orthopedic disease of dogs. Triple pelvic osteotomy (TPO) is a surgery that can be performed at 5 months of age, prior to the development of osteoarthritis. ...