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Novel targeted lipid prodrugs to improve cellular absorption of acyclovir and topical delivery to the eye via nanomicellar approach
Biotinylated lipid prodrugs of acyclovir (ACV) were designed to target the sodium dependent multivitamin transporter (SMVT) on the intestine and cornea to facilitate ACV cellular transport. All the prodrugs were screened ...
Fomulation and Delivery of Drugs for Macular Edema and Retinoblastoma; Synthesis and In Vitro Characterization of Doxorubicin Loaded Surface Modified Nanoparticles Using PLGA-PEG-PLGA Polymer
(University of Missouri--Kansas City, 2011-01-20)
Macular edema (ME) is caused by central extravascular swelling of the macula resulting in a significant loss of visual activity. Corticosteroids are widely used in the treatment of ME. In this project, nanoparticles of ...