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How do clinical prediction rules compare with joint fluid analysis in diagnosing gout?
(Family Physicians Inquiries Network, 2016)
Q: How do clinical prediction rules compare with joint fluid analysis in diagnosing gout? Evidence-based answer: Clinical prediction rules effectively diagnose gout without joint fluid analysis. The American College of Rheumatology clinical...
Does knuckle popping lead to arthritis?
(Family Physicians Inquiries Network, 2016)
Q: Does knuckle popping lead to arthritis? Evidence-based answer: No, habitual knuckle popping, or cracking (over the course of several decades) isn't associated with clinical or radiographic evidence of osteoarthritis (strength of recommendation...
Does caffeine intake during pregnancy affect birth weight?
(Family Physicians Inquiries Network, 2016)
more than 300 mg of caffeine per day is associated with a clinically trivial, and statistically insignificant (less than 1 ounce), reduction in birth weight, compared with consuming no caffeine (strength of recommendation: B, randomized controlled trial...
Deliver or wait with late preterm membrane rupture?
(Family Physicians Inquiries Network, 2016)
of clinical indications for delivery, consider expectant management in women with premature rupture of membranes in late preterm stages (34 weeks to 36 weeks, 6 days). Stength of recommendation: B: Based on one well-designed randomized controlled trial: Morris...
A more palatable alternative to oral rehydration therapy for kids
(Family Physicians Inquiries Network, 2016)
A more palatable alternative to oral rehydration therapy for kids. Parents no longer need to struggle to get their kids to drink electrolyte solutions during episodes of mild gastroenteritis; apple juice works just as well. ...
Monitoring home BP readings just got easier
(Family Physicians Inquiries Network, 2016)
method using blood pressure diaries to assess blood pressure control. Ann Fam Med. 2016;14:63-69....
Potential harms of long-term acne treatment with oral antibiotics
(Family Physicians Inquiries Network, 2020)
Clinical Inquiries question: What are the potential harms of long-term acne treatment with oral antibiotics? Evidence-based answer: Specific evidence attributing adverse effects to long-term acne treatment with oral antibiotics is lacking. However...
More isn't better with acute low back pain treatment
(Family Physicians Inquiries Network, 2016)
More isn't better with acute low back pain treatment Adding cyclobenzaprine or oxycodone/acetaminophen to naproxen for the treatment of acute low back pain does nothing more than increase adverse effects. Practice changer: ...
Aneuploidy screening: Newer noninvasive test gains traction
(Family Physicians Inquiries Network, 2016)
Favorable results from the 2 studies reviewed here have prompted ACOG to recommend that cell-free DNA screening be discussed with all pregnant patients. Practice changer: Discuss cell-free DNA testing when offering fetal ...
Resistant hypertension? Time to consider this fourth-line drug
(Family Physicians Inquiries Network, 2016)
Resistant hypertension? Time to consider this fourth-line drug For most adults with resistant hypertension, spironolactone is superior to doxazosin and bisoprolol as an adjunct to triple therapy. Practice changer: When a ...
Light therapy for nonseasonal major depressive disorder?
(Family Physicians Inquiries Network, 2016)
Light therapy for nonseasonal major depressive disorder? While bright light therapy already has a place in the treatment of seasonal affective disorder, a recent trial spotlights its utility beyond the winter months. ...
Go low or say No to aggressive systolic BP goals?
(Family Physicians Inquiries Network, 2016)
"Go low" or say "No" to aggressive systolic BP goals? The SPRINT trial demonstrated the benefits -- and risks -- of reaching a systolic target <120 mm Hg in non-diabetic patients at high risk for CV events. Here's who might ...
Acupuncture for low back pain
(Family Physicians Inquiries Network, 2020)
Clinical Inquiries question: Is acupuncture effective in improving pain relief for low back pain? Evidence-based answer: Acupuncture is an effective treatment for relief from low back pain, even when compared with other interventions (sham...
On-demand pill protocol protects against HIV
(Family Physicians Inquiries Network, 2016)
On-demand pill protocol protects against HIV: Finally, there's an effective prevention strategy -- other than condoms -- that can be used, as needed, by patients at high risk for HIV infection. Practice changer: Offer ...
Yeast infection in pregnancy? Think twice about fluconazole
(Family Physicians Inquiries Network, 2016)
Yeast infection in pregnancy? Think twice about fluconazole. This study's findings regarding the risk of miscarriage may mean it's time to forego fluconazole in favor of topical azoles as first-line treatment. Practice ...
Kidney stones? It's time to rethink those meds
(Family Physicians Inquiries Network, 2016)
Kidney stones? It's time to rethink those meds. Despite being recommended for ureteral stone expulsion, tamsulosin or nifedipine are no more effective than placebo. Practice changer: Do not prescribe tamsulosin or nifedipine ...
Ruling out PE in pregnancy
(Family Physicians Inquiries Network, 2020)
Can clinical probability and a high-sensitivity D-dimer test reliably and safely rule out pulmonary embolism during pregnancy? PRACTICE CHANGER: Use a clinical probability score to identify patients at low or intermediate risk for pulmonary embolism...
Hypoglycemia with insulin and sulfonylureas
(Family Physicians Inquiries Network, 2020)
Clinical Inquiries question: In patients with type 2 diabetes mellitus (T2DM), does the combination of insulin and sulfonylurea (SU) increase the risk of hypoglycemia? Evidence-based answer: The incidence of severe hypoglycemia in patients with T2DM...
Does breastfeeding affect the risk of childhood obesity?
(Family Physicians Inquiries Network, 2016)
breastfeeding rates during the first 3 to 6 months of life don't appear to alter body mass index (BMI) at 11 to 12 years of age (SOR: B, randomized clinical trial [RCT]). Introducing complementary (solid) foods before 3 months is associated with a 30% greater...
Which SSRIs most effectively treat depression in adolescents?
(Family Physicians Inquiries Network, 2016)
Q: Which SSRIs most effectively treat depression in adolescents? Evidence-based answer: We don' t know which selective serotonin reuptake inhibitors (SSRIs) are the most effective and safe because no studies have compared ...