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In situ polymerizing collagen for the development of 3D printed tissue engineering scaffolds
(University of Missouri--Columbia, 2018)
-inflammatory compounds such as gold nanoparticles and curcumin were also incorporated into the scaffolds post printing in order to further tailor the cellular responses to the scaffolds. Scanning electron microscopy and neutron activation analysis were performed...
Development of a flexible image-based approach for studying signal transduction in isolated arterioles
(University of Missouri--Columbia, 2007)
Myogenic constriction in arterioles occurs when membrane tension leads to smooth muscle depolarization and voltage-gated calcium channel activation. A barrier to understanding the exact signaling events is the limited ...
Effects of oxidative stress and Alzheimer's amyloid-beta peptide on astrocytes
(University of Missouri--Columbia, 2006)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Oxidative stress and deposition of amyloid-[beta] peptide (A[beta]) in brains have been hypothesized as causes of Alzheimer's disease (AD), and research ...
Development of a biosensor for the detection of Helicobacter hepaticus utilizing multi-functioning immobilization platforms
(University of Missouri--Columbia, 2010)
Optical biosensor development is a process involving the careful selection of the material for the immobilization platform, design of the detection mechanism and integration with optical and electronic equipment. The ability of biosensor...
Synthesis and application of semiconductor quantum dots in novel sensing applications
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] This thesis details the synthesis of CdSe/ZnS semiconductor nanocrystals (quantum dots). These quantum dots (QDs) show very interesting optical properties ...
Multi-scale self-assembly of nanoenergetic materials utilizing functionalized graphene
(University of Missouri--Columbia, 2020)
with Al and Bi2O3 nanoparticles, the FGO/Al/Bi2O3 showed a 60% enhancement in energy release and an all-solid-state reaction between Al and Bi2O3 as the fluorine significantly weakened the alumina shell protecting Al core. Iodinated reduced graphene oxide...
Development of a fluorescence-based protease biosensor using nanoscale platforms
(University of Missouri--Columbia, 2010)
The development of a protease biosensor utilizing nanomaterials is presented in this dissertation. Peptide substrates and nanomaterial platforms were investigated to increase the sensitivity and response time for the ...
Optical stimulation of quantal exocytosis on transparent microchips
(University of Missouri--Columbia, 2007)
) film was sputter-deposited onto glass coverslips, which were then patterned into 24 cell-sized working electrodes (2̃0 [mu]m by 20 [mu]m). We loaded bovine chromaffin cells with acetoxymethyl (AM) ester derivatives of the Ca²⁺ cage NP-EGTA and Ca...
Risk prediction and an injectable collagen material for intervertebral disc degeneration
(University of Missouri--Columbia, 2021)
This research primarily focuses on early prediction and treatment for intervertebral disc degeneration (IVDD). In Phase 1, machine learning algorithms were evaluated to predict the risk of intervertebral disc degeneration ...
Quantification of cell attachment on different materials as candidate electrodes for measurement of quantal exocytosis
(University of Missouri--Columbia, 2008)
A high throughput lab-on-a-chip device is being developed for single cell capture for the purpose of high time resolution quantal exocytosis measurement with high probability of cell docking. This device makes use of DLC ...
Creating a zero-waste soy processing system and developing vitamin B12 fortified non-GMO high oleic soy-based products using encapsulation technology
(University of Missouri--Columbia, 2023)
by preventing it from degrading with environmental change. Currently, there are many encapsulation techniques used to entrap core material with appropriate wall matrices. Spray drying is one of the most appropriate encapsulation techniques for thermosensitive...
Nanofibrillation of lignocellulosic biomass into lignin-containing nanocellulose for 3D printing and antimicrobial applications
(University of Missouri--Columbia, 2022)
Lignin-containing nanocellulose (LNC) has become an emerging subcategory of nanocellulose. Compared toedtraditional pure nanocellulose, LNC contains lignin and hemicellulose that are not fully removed from original ...
Optical reflectance in fibrous tissues and skeletal muscles
(University of Missouri--Columbia, 2008)
We studied diffuse optical reflectance in two anisotropic biological tissues: high moisture soy extrudates and skeletal muscles. High moisture extrusion of soy proteins can produce healthy alternative protein sources that ...