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What are the indications for tonsillectomy in children?
(Family Physicians Inquiries Network, 2002)
. (Grade of recommendation: B, based on low-quality randomized controlled trials [RCTs]). The evidence supporting tonsillectomy for recurrence of sore throat is controversial. There is insufficient evidence to recommend other potential indications. (Grade...
What is the best way to evaluate acute diarrhea?
(Family Physicians Inquiries Network, 2002)
Limited evidence delineates the relative probabilities of causes of acute diarrhea, typically defined as a diarrheal disease lasting 14 days or fewer, in the developed world. Viruses (rotavirus, Norwalk, and other enteric viruses) are responsible...
How effective are nasal steroids combined with nonsedating antihistamines for seasonal allergic rhinitis?
(Family Physicians Inquiries Network, 2002)
For treating seasonal allergic rhinitis, inhaled nasal corticosteroids are superior to nonsedating antihistamines (Grade of recommendation: A, based on a large meta-analysis of randomized controlled trials [RCTs]). Combining nasal steroids...
How effective is desmopressin for primary nocturnal enuresis?
(Family Physicians Inquiries Network, 2003)
of recommendation [SOR]: A, based on meta-analysis). Evidence suggests that the benefits of desmopressin are temporary, with a high relapse rate once treatment is discontinued (SOR: B). However, long-term therapy with occasional weaning attempts is a safe option...
Does evidence support the use of supplements to aid in BP control?
(Family Physicians Inquiries Network, 2020)
Q: Does evidence support the use of supplements to aid in BP control? Evidence-based answer: Yes. A number of well-tolerated natural therapies have been shown to reduce systolic and diastolic blood pressure (BP). (See TABLE1-8 for summary.) However...
What effects -- if any -- does marijuana use during pregnancy have on the fetus or child?
(Family Physicians Inquiries Network, 2017)
Q: What effects -- if any -- does marijuana use during pregnancy have on the fetus or child? Evidence-based answer: The effects are unclear. Marijuana use during pregnancy is associated with clinically unimportant lower birth weights (growth...
For fibromyalgia, which treatments are the most effective?
(Family Physicians Inquiries Network, 2005)
well-being and have a moderate beneficial effect on tenderness and stiffness (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs]). Selective serotonin reuptake inhibitors (SSRIs) may moderately...
Is an outpatient workup safe for patients with a transient ischemic attack?
(Family Physicians Inquiries Network, 2004)
There is no compelling evidence that outpatient diagnostic workup of patients with transient ischemic attack (TIA) is less safe than inpatient workup, or that hospitalization prevents stroke or improves stroke outcomes after TIA (strength...
Is therapy based on endoscopy results better than empiric therapy for dyspepsia?
(Family Physicians Inquiries Network, 2005)
In the initial management of dyspepsia for patients without "alarm" symptoms (weight loss, recurrent vomiting, dysphagia, anemia, evidence of bleeding, onset of dyspepsia after age 45 years), therapy based on the results of early endoscopy...
At what age do patients no longer need colorectal cancer screening?
(Family Physicians Inquiries Network, 2001)
Good evidence supports fecal occult blood testing (FOBT) for patients up to age 75 (grade of recommendation: A, based on systematic review of randomized controlled trials). There is insufficient evidence to recommend for or against colorectal cancer...
What illnesses contraindicate immunization?
(Family Physicians Inquiries Network, 2005)
The Advisory Council on Immunization Practices (ACIP) reports that the only contraindication for all vaccines is a history of severe allergic reaction to a previous vaccine or vaccine constituent (strength of recommendations: C, based predominantly...
Other than anticoagulation, what is the best therapy for those with atrial fibrillation?
(Family Physicians Inquiries Network, 2004)
Rate control with long-term anticoagulation is recommended for most patients with atrial fibrillation (strength of recommendation [SOR]: A, based on randomized controlled trials [RCTs]). A rhythm-control strategy provides no survival or quality...
Does combining aspirin and warfarin decrease the risk of stroke for patients with nonvalvular atrial fibrillation?
(Family Physicians Inquiries Network, 2004)
(NVAF) (strength of recommendation [SOR]: A, based on randomized controlled trials). Aspirin therapy at a dose of 75 to 325 mg reduces the risk of stroke to a lesser degree and may be useful for low-risk patients with NVAF or patients at high risk...
What is the best treatment for impacted cerumen?
(Family Physicians Inquiries Network, 2002)
Docusate sodium given 15 minutes before irrigation is most effective for facilitating cerumen removal during a single office visit. (Grade of recommendation: B, based on head-to-head trials that lacked irrigationonly arms.) Treatment with 5% urea...
What's the best way to screen for anxiety and panic disorders?
(Family Physicians Inquiries Network, 2007)
The GAD-7 has the best evidence and utility in the primary care setting for generalized anxiety disorder (strength of recommendation [SOR]: A), while the proprietary Quick PsychoDiagnostics Panel (QPD) has the best operating characteristics...
How safe and effective is ondansetron for nausea and vomiting in pregnancy?
(Family Physicians Inquiries Network, 2019)
Q: How safe and effective is ondansetron for nausea and vomiting in pregnancy? Evidence-based answer: oral ondansetron is more effective than a combination of pyridoxine and doxylamine for outpatient treatment of nausea and vomiting in pregnancy...
Hospitalist update : why does team-based care matter to hospitalists?
(University of Missouri, Department of Medicine, Division of Hospital Medicine, 2011-07)
Does cranberry juice prevent or treat urinary tract infection?
(Family Physicians Inquiries Network, 2003)
[ARR]) compared with placebo (number needed to treat [NNT]=58) (strength of recommendation: A). There is no conclusive evidence that cranberry juice effectively treats UTI (SOR: D)....
Do patients with type 2 diabetes who aren't taking insulin benefit from self-monitoring blood glucose?
(Family Physicians Inquiries Network, 2013)
reviews and meta-analyses of disease-oriented evidence). Patients with a baseline HbA1c <8% who self-monitor don't reduce their HbA1c levels, but patients with a baseline HbA1c >8% do (SOR: B, systematic reviews and meta-analyses of disease...
What is the evaluation and treatment strategy for Raynaud's phenomenon?
(Family Physicians Inquiries Network, 2005)
Raynaud's phenomenon is diagnosed by history,
which also plays a key role in distinguishing
primary from secondary Raynaud's phenomenon
(strength of recommendation [SOR]: C, based
on expert opinion). The initial treatment includes conservative...