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Do oral decongestants have a clinically significant effect on BP in patients with hypertension?
(Family Physicians Inquiries Network, 2017)
Q: Do oral decongestants have a clinically significant effect on BP in patients with hypertension? Evidence-based answer: It is unclear. Pseudoephedrine causes an average increase of 1.2 mm Hg in systolic blood pressure (BP) in patients...
How effective is desmopressin for primary nocturnal enuresis?
(Family Physicians Inquiries Network, 2003)
of recommendation [SOR]: A, based on meta-analysis). Evidence suggests that the benefits of desmopressin are temporary, with a high relapse rate once treatment is discontinued (SOR: B). However, long-term therapy with occasional weaning attempts is a safe option...
What's the best test for underlying osteomyelitis in patients with diabetic foot ulcers?
(Family Physicians Inquiries Network, 2015)
, evidence-based guidelines)....
What are the repercussions of disclosing a medical error?
(Family Physicians Inquiries Network, 2008)
Physicians and their staff may experience a resolution of anxiety and guilt that can improve their well-being (strength of recommendation [SOR]: C, based on survey data). Full disclosure has little effect, however, on the likelihood that an injured...
What is the evaluation and treatment strategy for Raynaud's phenomenon?
(Family Physicians Inquiries Network, 2005)
Raynaud's phenomenon is diagnosed by history,
which also plays a key role in distinguishing
primary from secondary Raynaud's phenomenon
(strength of recommendation [SOR]: C, based
on expert opinion). The initial treatment includes conservative...
Glycemic Control in Patients with Type 2 Diabetes
(Family Physicians Inquiries Network, 2007)
There is no clearly superior oral agent for glycemic control in patients with type 2 diabetes. (Strength of Recommendation [SOR]: C) Metformin (Glucophage) has shown additional benefit when compared with other treatments ...
Time to conception after miscarriage : how long to wait?
(Family Physicians Inquiries Network, 2019)
Q: Time to conception after miscarriage: how long to wait? Evidence-based answer: an interpregnancy interval (IPI) of < 6 months following miscarriage is associated with an increased live birth rate in subsequent pregnancy, lower risks of preterm...
Which drugs are best when aggressive Alzheimer's patients need medication?
(Family Physicians Inquiries Network, 2010)
of antiepileptic agents is conflicting (SOR: C, inconsistent patient-oriented evidence). Valproate is ineffective for treating aggression (SOR: C, very small RCT). No data exist to guide long-term medication use. All available studies lasted no longer than 12 weeks...
How safe and effective is ondansetron for nausea and vomiting in pregnancy?
(Family Physicians Inquiries Network, 2019)
Q: How safe and effective is ondansetron for nausea and vomiting in pregnancy? Evidence-based answer: oral ondansetron is more effective than a combination of pyridoxine and doxylamine for outpatient treatment of nausea and vomiting in pregnancy...
Does birth weight predict childhood obesity?
(Family Physicians Inquiries Network, 2008)
A birth weight greater than 4,000 g is associated with an increased risk of obesity in both childhood and adolescence (strength of recommendation [SOR]: B, systematic review and multiple cohort studies).
Is therapy based on endoscopy results better than empiric therapy for dyspepsia?
(Family Physicians Inquiries Network, 2005)
In the initial management of dyspepsia for patients without "alarm" symptoms (weight loss, recurrent vomiting, dysphagia, anemia, evidence of bleeding, onset of dyspepsia after age 45 years), therapy based on the results of early endoscopy...
What are the benefits/risks of giving betamethasone to women at risk of late preterm labor?
(Family Physicians Inquiries Network, 2018)
Q: What are the benefits/risks of giving betamethasone to women at risk of late preterm labor? Evidence-based answer: Giving betamethasone to women at risk for delivery between 34 weeks 0 days and 36 weeks 6 days can lower by almost 40...
Diagnosing Von Willebrand Disease
(Family Physicians Inquiries Network, 2010)
The diagnosis of vWD requires two clinical criteria: (1) a personal history, family history, or physical evidence of mucocutaneous bleeding and (2) a qualitative or quantitative decrease in functional activity of von Willebrand factor (v...
Appetite Suppressants as Adjuncts for Weight Loss
(Family Physicians Inquiries Network, 2011)
. (Strength of Recommendation: B, based on a randomized trial and a meta-analysis.) No current evidence is available on the long-term risks and benefits of these medications, or the most appropriate time to initiate appetite suppressant therapy as part of a...
How best to help kids lose weight
(Family Physicians Inquiries Network, 2010)
Screen children and adolescents for obesity and offer them multifaceted weight loss interventions, based on new evidence (and a recent US Preventive Services Task Force [USPSTF] recommendation) of their effectiveness. Consider adding a weight loss...
At what age do patients no longer need colorectal cancer screening?
(Family Physicians Inquiries Network, 2001)
Good evidence supports fecal occult blood testing (FOBT) for patients up to age 75 (grade of recommendation: A, based on systematic review of randomized controlled trials). There is insufficient evidence to recommend for or against colorectal cancer...
Supplemental oxygen : more isn't always better
(Family Physicians Inquiries Network, 2019)
Supplemental oxygen: more isn't always better. A recent study says that in certain populations supplemental oxygen above certain levels can increase mortality. PRACTICE CHANGER Do not use liberal oxygen therapy (SpO2> 96%) in acutely ill adults...
What is the best test for peripheral vascular disease?
(Family Physicians Inquiries Network, 2008)
An ankle-brachial index is best for evaluating patients with symptoms of claudication (strength of recommendation [SOR]: B, multiple cohort studies). That said, duplex ultrasonography or magnetic resonance angiography may ...
What is the best treatment for plant-induced contact dermatitis?
(Family Physicians Inquiries Network, 2013)
It's unclear which treatment is best, because there have been no head-to-head comparisons of treatments for Rhus (plant-induced) contact dermatitis. That said, topical high-potency steroids slightly improve pruritus and ...
What is the best treatment for impetigo?
(Family Physicians Inquiries Network, 2014)
Q. What is the best treatment for impetigo? A. Although evidence is lacking to support a single best treatment for impetigo, topical mupirocin, fusidic acid, gentamicin, and retapamulin are all at least 20% more likely than placebo to produce cure...