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Need to Know, Number 09, September 2008
(Sinclair School of Nursing, 2008-09)
SSRIs for depression/heart failure patients? Not so fast
(Family Physicians Inquiries Network, 2017)
This study should put to rest the practice of starting SSRIs in depressed patients with heart failure in an attempt to affect CVD outcomes. PRACTICE CHANGER: Do not prescribe selective serotonin reuptake inhibitors to improve depression and reduce...
Treatment of Otitis Media with Perforated Tympanic Membrane
(Family Physicians Inquiries Network, 2009)
Acute otitis media with tympanic membrane perforation in children should be treated with an oral antibiotic. (Strength of Recommendation [SOR]: A, based on meta- analysis of randomized controlled trials [RCTs]). Topical ciprofloxacin...
Screening Mammography in Women 40 to 49 Years of Age
(Family Physicians Inquiries Network, 2004)
While there is strong agreement among experts and evidence in the literature to recommend that women 50 to 69 years of age undergo screening with mammography for breast cancer, the question of screening women 40 to 49 years of age is controversial...
Evidence based resources for young adults at risk for depression in Boone County, MO
(University of Missouri--Columbia., 2017)
"To identify the preventable risk factors leading to depression through a literature review. To recognize the behavioral changes, and the cost-effective therapeutic tools that young adults can use to improve the prevention ...
What is the best management for patients with evidence of asymptomatic ischemia on exercise stress testing?
(Family Physicians Inquiries Network, 2007)
-EST Heart Rate Recovery. For patients who have a low-risk DTS, the 4-year mortality is less than 1% to 2%; therefore, risk-factor reduction without further investigation is appropriate (strength of recommendation: B, based on cohort studies and consensus...
Is there a well-tested tool to detect drug-seeking behaviors in chronic pain patients?
(Family Physicians Inquiries Network, 2008)
There is no well-tested, easily administered screening tool to detect drug-seeking behaviors in primary care patients taking long-term opioids or being considered for such therapy (strength of recommendation [SOR]: C, ...
Does tranexamic acid reduce mortality in women with postpartum hemorrhage?
(Family Physicians Inquiries Network, 2019)
Q: Does tranexamic acid reduce mortality in women with postpartum hemorrhage? EVIDENCE-BASED ANSWER: Yes. When used in conjunction with the standard of care, 1 g intravenous (IV) tranexamic acid given 1 to 3 hours after delivery is associated with a...
Which oral nonopioid agents are most effective for OA pain?
(Family Physicians Inquiries Network, 2019)
Q Which oral nonopioid agents are most effective for OA pain? Evidence-based answer: nonsteroidal anti-inflammatory drugs (nsaids), when used at the maximum clinically effective dose, reduce osteoarthritis (OA) pain in large joints more effectively...
Does brief physician counseling promote weight loss?
(Family Physicians Inquiries Network, 2011)
While physician counseling alone isn't more effective for weight loss than usual care (strength of recommendation [SOR]: A, larger randomized controlled trials [RCTs]), counseling (adults) as part of a multidisciplinary ...
How do antidepressants affect sexual function?
(Family Physicians Inquiries Network, 2013)
Evidence-based answer: patients treated with elective serotonin reuptake inhibitors (SSRIs) and the serotonin/norepinephrine reuptake inhibitor (SNRI) venlafaxine have significantly higher rates of overall sexual dysfunction--including desire...
Effects of high fat loading on substrate utilization and performance during intermittent exercise in trained athletes
(University of Missouri--Columbia, 2008)
on a 40 min intermittent bout of treadmill running at work/recovery ratios of 6:9 s and 24:36 s at speeds that produced an RER between 0.95 and 0.99 while gas was collected, then in elliptical locomotion in which distance traveled (Km) and power output...
How should you treat Candida vaginitis in patients on antibiotics?
(Family Physicians Inquiries Network, 2007)
Oral and intravaginal antifungals for the treatment of uncomplicated vulvovaginal candidiasis (VVC) have similar effectiveness (strength of recommendation [SOR]: A, systematic review). However, no randomized controlled ...
Addressing chronic back pain in adults
(2023)
"Reduce the number of opioid drug-related overdose deaths in U.S. adults. Reduce the incidence of major adverse opioid effects for adults with chronic back pain (CBP), such as tolerance, dependence, misuse, and addiction ...
What risk factors contribute to C difficile diarrhea?
(Family Physicians Inquiries Network, 2011)
Certain antibiotics and using 3 or more antibiotics at one time are associated with Clostridium difficile-associated diarrhea (CDAD) (strength of recommendation [SOR]: B, 1 heterogeneous systematic review and several ...
Does evidence support the use of supplements to aid in BP control?
(Family Physicians Inquiries Network, 2020)
Q: Does evidence support the use of supplements to aid in BP control? Evidence-based answer: Yes. A number of well-tolerated natural therapies have been shown to reduce systolic and diastolic blood pressure (BP). (See TABLE1-8 for summary.) However...
Does a Low-Sodium Diet Reduce Blood Pressure?
(Family Physicians Inquiries Network, 2004)
Reducing sodium intake does lead to a slightly lower average blood pressure. However, no evidence from controlled trials proves that reducing sodium intake decreases morbidity or mortality, or proves that modest sodium restriction is harmful...
How often does long-term PPI therapy cause clinically significant hypomagnesemia?
(Family Physicians Inquiries Network, 2018)
Q: How often does long-term PPI therapy cause clinically significant hypomagnesemia? EVIDENCE-BASED ANSWER: Rarely. Proton pump inhibitors (PPIs) may be associated with decreases in serum magnesium laboratory values to below 1.6 to 1.8 mg...
Does pneumococcal conjugate vaccine prevent otitis media?
(Family Physicians Inquiries Network, 2011)
Yes, if the pneumococcal conjugate vaccine (PCV) series is given before 12 months of age. Vaccination before 12 months is associated with a statistically significant reduction in the incidence of both acute (AOM) and ...
Missouri hybrid corn yield trials, 1958
(University of Missouri, Agricultural Experiment Station, 1959)