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Does turmeric relieve inflammatory conditions?
(Family Physicians Inquiries Network, 2011)
Limited evidence suggests that turmeric and its active compound, curcumin, are effective for rheumatoid arthritis and other inflammatory conditions (strength of recommendation [SOR]: C, primarily low-quality cohort studies with small patient numbers...
How can we minimize recurrent ankle sprains?
(Family Physicians Inquiries Network, 2011)
Using external ankle supports during physical activity significantly reduces the likelihood of primary and secondary sprains (strength of recommendation [SOR]: A, systematic review). Proprioception rehabilitation substantially ...
Clinical Indicators of Obstructive Sleep Apnea
(Family Physicians Inquiries Network, 2011)
Clinical indicators (e.g., sex, snoring severity, history of apnea, age, menopausal status, waist-to-hip ratio, body habitus) can predict OSA as diagnosed using overnight polysomnography or sleep study. (Strength of Recommendation: B, based...
Antidepressants for the Treatment of Insomnia in Patients with Depression
(Family Physicians Inquiries Network, 2011)
to improve subjective ratings of sleep quality. (Strength of Recommendation: B, based on one qualitative study and one meta-analysis.)...
Appetite Suppressants as Adjuncts for Weight Loss
(Family Physicians Inquiries Network, 2011)
. (Strength of Recommendation: B, based on a randomized trial and a meta-analysis.) No current evidence is available on the long-term risks and benefits of these medications, or the most appropriate time to initiate appetite suppressant therapy as part of a...
What is the prognosis for patients with chronic urticaria?
(Family Physicians Inquiries Network, 2011)
The prognosis for chronic urticaria in primary care is unknown; studies in dermatology clinics in multiple countries report complete resolution in approximately one-third of patients with idiopathic chronic urticaria over ...
Antibiotics for Viral Upper Respiratory Tract Infections in Children
(Family Physicians Inquiries Network, 2011)
of Recommendation [SOR]: A, based on systematic reviews of randomized controlled trials [RCTs].) Using strategies that delay or avoid antibiotic prescription for viral upper respiratory tract infections will significantly reduce antibiotic use without increasing...
Do NSAIDs impede fracture healing?
(Family Physicians Inquiries Network, 2011)
Nonsteroidal anti-inflammatory drugs (NSAIDs) don't appear to impair clinical fracture healing (strength of recommendation [SOR]: B, inconsistent evidence from a randomized controlled trial [RCT] and retrospective studies). Even though animal...
Is cinnamon safe and effective for treating lipid disorders?
(Family Physicians Inquiries Network, 2011)
Insufficient evidence exists to determine whether cinnamon improves outcomes in patients with lipid disorders. In healthy patients without hyperlipidemia, cinnamon doesn't change lipid levels but does cause mild gastrointestinal symptoms...
Which combination drug therapies are most effective for hypertension?
(Family Physicians Inquiries Network, 2011)
Insufficient evidence exists to determine which specific combinations most effectively decrease cardiovascular morbidity and mortality, although combinations of hypertension medications at lower doses generally reduce cardiovascular outcomes (stroke...
Which smoking cessation interventions work best?
(Family Physicians Inquiries Network, 2011)
Nicotine replacement therapy (NRT), bupropion, nortriptyline, clonidine, and varenicline are all effective, although insufficient evidence exists to recommend one intervention over another (SOR: A, systematic reviews). Effective nonpharmacologic...
Is it safe to vaccinate children against varicella while they're in close contact with a pregnant woman?
(Family Physicians Inquiries Network, 2011)
All healthy children without evidence of immunity to varicella who are living in a household with a susceptible pregnant woman should be vaccinated (strength of recommendation [SOR]: C, expert opinion). The risk of transmission of vaccine virus...
Statins for patients with nonalcoholic fatty liver?
(Family Physicians Inquiries Network, 2011)
Treat patients with hyperlipidemia and presumed nonalcoholic fatty liver disease with atorvastatin to reduce the risk of cardiovascular events. Stength of recommendation: B: Based on a single prospective randomized controlled trial (RCT)....
From the journals
(University of Missouri, Department of Medicine, Division of Hospital Medicine, 2011-05)
From the journals
(University of Missouri. Department of Medicine. Division of Hospital Medicine, 2011-05)
Is your patient still using rosiglitazone?
(Family Physicians Inquiries Network, 2011)
Do not initiate rosiglitazone therapy for patients with diabetes, and consider switching those who are already taking it to pioglitazone. Stength of recommendation: A: Based on a meta-analysis of 56 randomized trials....
Consider this option for heavy menstrual bleeding
(Family Physicians Inquiries Network, 2011)
Offer tranexamic acid to patients with heavy menstrual bleeding. The extended-release formulation is effective and well tolerated. Stength of recommendation: A: Based on 1 good-quality randomized controlled trial (RCT)....
What is the best way to treat Morton's neuroma?
(Family Physicians Inquiries Network, 2011)
by corticosteroid injections and, finally, surgery (strength of recommendation [SOR]: C, case series). Injecting sclerosing alcohol depends on the provider's access to and comfort with ultrasound, but the evidence is insufficient to recommend it routinely (SOR: C...
What are the current treatment and monitoring recommendations for hepatitis C virus (HCV)?
(Family Physicians Inquiries Network, 2001)
evidence shows that treatment with PEG-interferon alpha-2b and ribavirin with weight-based dosing achieved an 82% sustained viral response. (Grade of recommendation: A [dual therapy]; D [all other recommendations].)...
Ferning in amniotic fluid: Is it a useful indicator of ruptured membranes?
(Family Physicians Inquiries Network, 2011)
The presence of arborized crystals (ferning) in amniotic fluid is both sensitive (74%-100%) and specific (77%-100%) for diagnosing rupture of membranes in laboring women who report loss of fluid (strength of recommendation ...