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What treatment is best for hypertrophic scars and keloids?
(Family Physicians Inquiries Network, 2011)
No one treatment is best (strength of recommendation [SOR]: C, meta-analysis of heterogenous studies); no good evidence exists comparing treatments with each other. Triamcinolone injections, triamcinolone injections combined with excision...
Chronic urticaria: What diagnostic evaluation is best?
(Family Physicians Inquiries Network, 2011)
(strength of recommendation: B, inconsistent or limited-quality evidence)....
How can we minimize recurrent ankle sprains?
(Family Physicians Inquiries Network, 2011)
Using external ankle supports during physical activity significantly reduces the likelihood of primary and secondary sprains (strength of recommendation [SOR]: A, systematic review). Proprioception rehabilitation substantially ...
What's the best way to relieve mastitis in breastfeeding mothers?
(Family Physicians Inquiries Network, 2011)
Frequent breast emptying helps both infectious and noninfectious mastitis (strength of recommendation [SOR]: A, 1 randomized controlled trial [RCT]). Antibiotics may be useful for women with positive milk cultures (SOR: ...
When is discectomy indicated for lumbar disc disease?
(Family Physicians Inquiries Network, 2011)
Emergent discectomy is indicated in the presence of cauda equina and severe, progressive neuromotor deficits (strength of recommendation [SOR]: C, expert opinion). Elective discectomy for sciatica caused by lumbar disc ...
Postcholecystectomy diarrhea: What relieves it?
(Family Physicians Inquiries Network, 2011)
A trial of a bile acid binder such as cholestyramine or colestipol may benefit patients with postcholecystectomy diarrhea (strength of recommendation [SOR]: C, case series). Although postcholecystectomy diarrhea is uncommon ...
Ferning in amniotic fluid: Is it a useful indicator of ruptured membranes?
(Family Physicians Inquiries Network, 2011)
The presence of arborized crystals (ferning) in amniotic fluid is both sensitive (74%-100%) and specific (77%-100%) for diagnosing rupture of membranes in laboring women who report loss of fluid (strength of recommendation ...
Which combination drug therapies are most effective for hypertension?
(Family Physicians Inquiries Network, 2011)
Insufficient evidence exists to determine which specific combinations most effectively decrease cardiovascular morbidity and mortality, although combinations of hypertension medications at lower doses generally reduce cardiovascular outcomes (stroke...
What's best for croup?
(Family Physicians Inquiries Network, 2011)
in moderate-to-severe croup (SOR: C, limited-quality disease-oriented evidence). The role of heliox in moderate to severe croup remains uncertain. Studies to date have been inadequate (SOR: C, limited-quality disease-oriented evidence). Humidified air provides...
Is your patient still using rosiglitazone?
(Family Physicians Inquiries Network, 2011)
Do not initiate rosiglitazone therapy for patients with diabetes, and consider switching those who are already taking it to pioglitazone. Stength of recommendation: A: Based on a meta-analysis of 56 randomized trials....
Is it safe to vaccinate children against varicella while they're in close contact with a pregnant woman?
(Family Physicians Inquiries Network, 2011)
All healthy children without evidence of immunity to varicella who are living in a household with a susceptible pregnant woman should be vaccinated (strength of recommendation [SOR]: C, expert opinion). The risk of transmission of vaccine virus...
Introduction to Clinical Inquiries : new series by the Family Physicians Inquiries Network
(Family Physicians Inquiries Network, 2020)
Introduction to Clinical Inquiries and FPIN. The Clinical Inquiries were included in Canadian Family Physician beginning March 2020.
What are the current treatment and monitoring recommendations for hepatitis C virus (HCV)?
(Family Physicians Inquiries Network, 2001)
evidence shows that treatment with PEG-interferon alpha-2b and ribavirin with weight-based dosing achieved an 82% sustained viral response. (Grade of recommendation: A [dual therapy]; D [all other recommendations].)...
What is the long-term educational outlook for youngsters with ADHD?
(Family Physicians Inquiries Network, 2011)
Children and adolescents with attention defi cit hyperactivity disorder (ADHD) complete fewer years of school, graduate from high school at a lower rate, and are less likely to enroll in graduate school. Older adolescents and young adults with ADHD...
Missouri hospitalist, issue 39 (2011 July-August)
(University of Missouri. Department of Medicine. Division of Hospital Medicine, 2011-07)
Missouri hospitalist, issue 39 (2011 July-August)
(University of Missouri. Department of Medicine. Division of Hospital Medicine, 2011-07)
Which smoking cessation interventions work best?
(Family Physicians Inquiries Network, 2011)
Nicotine replacement therapy (NRT), bupropion, nortriptyline, clonidine, and varenicline are all effective, although insufficient evidence exists to recommend one intervention over another (SOR: A, systematic reviews). Effective nonpharmacologic...
Should you test for H pylori in patients with nonulcer dyspepsia?
(Family Physicians Inquiries Network, 2011)
Helicobacter pylori in creases the risk of developing peptic ulcer disease (strength of recommendation [SOR]: B, cohort study), but there is no evidence that treating H pylori reduces that risk. Treating H pylori in patients with nonulcer dyspepsia...
Colicky baby? Here's a surprising remedy
(Family Physicians Inquiries Network, 2011)
This article suggests that parents of colicky breastfed infants try probiotics (Lactobacillus reuteri), which can significantly reduce daily crying time with no adverse effects. Stength of recommendation: A: A good-quality ...
Are serum uric acid levels always elevated in acute gout?
(Family Physicians Inquiries Network, 2011)
acute gout attacks (SOR: B, extrapolated from prospective cohorts)....