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Three essays on phosphorus runoff and water quality
(University of Missouri--Columbia, 2019)
efforts to limit both residential and agricultural nonpoint source pollution. The results could be helpful policy makers to target specific regions to initiate environmental policies and extension efforts for designing educational programs to increase...
Development of translational models for intervertebral disc degeneration using a comparative approach for canine and human patients
(University of Missouri--Columbia, 2020)
with manifestations of symptomatic IVD disease (IVDD). IVDD spontaneously occurs in canine and human populations. As such, dogs can serve as highly relevant and ethical preclinical models for both human and canine IVDD. Chondrodystrophic (CD) and non...
Evolution, transmission, and clinical impacts of SARS-CoV-2 and influenza viruses
(University of Missouri--Columbia, 2023)
provided deeper insights into how an influenza and SARS-CoV-2 viruses emerge, evolve, and spread in humans and revealed how the intricate interplay between host, virus and environmental attributes affect disease severity of SARS-CoV-2 infection. Thus...
Phenolics in red wine pomace and their potential application in animal and human health
(University of Missouri--Columbia, 2008)
animal and human health....
Development of tissue based biomaterials for articular cartilage injuries
(University of Missouri--Columbia, 2020)
oxygen species production from interleukin-1beta stimulated human chondrocyte cells with addition of anti-inflammatory agent, curcumin. Finally, use of the developed liquid collagen as a potential bioink for 3D printing was investigated....
Phytoplankton response to water quality threats in Midwest reservoirs
(University of Missouri--Columbia, 2021)
Harmful cyanobacterial blooms and invasive species threaten water quality. These threats are expected to worsen in the future, emphasizing the need for creative management solutions and a thorough understanding of their ...
Effects of stress, genetics, and environment on microbiome composition in western corn rootworm (Diabrotica virgifera virgifera Leconte)
(University of Missouri--Columbia, 2023)
Increased study of microbiomes illuminated the diversity of roles microorganism play across ecosystems. For agricultural systems, microbiomes represent a new frontier to potentially improve plant, animal, and human health, while increasing...
Cryo-EM reveals how adeno-associated virus engages its receptor AAVR and an investigation of the GPR108 ectodomain
(University of Missouri--Columbia, 2022)
-enveloped virus, the protein shell of AAV is responsible for all of the host interactions from cell entry to gene delivery. With further study of the AAV structure and how AAV engages with human cells and the immune system we hope to create a roadmap of the AAV...
Modification of fatty acid composition in soybean seeds to improve soybean oil quality and functionality
(University of Missouri--Columbia, 2011)
acid content. Combination of two mutant FAD2-1A and FAD2-1B with mutant FAD3A or mutant FAD3C or both resulted in high oleic acid content of 80 - 85% and linolenic acid content in the range from 1.5 - 4%. Perfect molecular markers associated...
Biogeochemistry and inorganic geochemistry as indicators of the paleoenvironment and paleohydrology of the Al-Azraq Basin, Jordan
(2013)
This study investigates the biogeochemical and inorganic geochemical
indicators for past environments and paleohydrology of a high resolution sediment record
from the Al-Azraq Basin, Jordan. The second largest basin in ...
High throughput profiling of transcription factors involved in soybean root growth under water deficit
(University of Missouri--Columbia, 2009)
. Among these were zinc-finger protein, MYB-related protein, GmNAC3, GmNAC4, and bZIP transcription factors. These TFs were differentially expressed in distinct root regions, and therefore they can be targeted for functional characterization and further...
Hormonal and genetic control of leaf and vein development in maize
(University of Missouri--Columbia, 2022)
Grasses (Poaceae) have successfully colonized diverse terrestrial ecosystems and impacted human civilization by producing the bulk of world food supply. The grass leaf is distinct for having a sheathing base and strap-like blade -- an evolutionary...
Reflux, aspiration and respiratory disease in dogs : clinical consideration and advances in aerodigestive diagnostics
(University of Missouri--Columbia, 2019)
The aspiration of gastric contents into the respiratory tract has been associated with the development and progression of multiple respiratory diseases in humans. In veterinary medicine the term "aspiration" is considered synonymous with "aspiration...
Investigation of the thermostability and activity of biomolecules in bio-friendly deep eutectic solvents
(University of Missouri--Columbia, 2023)
DESs in an array of biomolecule-driven purposes and illustrate the versatility and potential of these unique, environmentally responsible solvents for next-generation biotechnological and biomedical applications....
Creating a zero-waste soy processing system and developing vitamin B12 fortified non-GMO high oleic soy-based products using encapsulation technology
(University of Missouri--Columbia, 2023)
their nutritional requirements. Vitamin B12 is soluble in water and is highly susceptible to changes in pH and temperature; it easily degrades under altered environmental conditions. Encapsulation of vitamin B12 may help boost its shelf life with targeted release...
The synthesis and characterization of 1,1'-disubstituted ferrocene imine Schiff base ligand systems for use as potential environmental heavy metal cationic sensors
(University of Missouri--Columbia, 2008)
Heavy metals in the environment such as Cd, Hg and Pb are toxic to life forms. They can enter the ecological system through both natural and industrial sources. By developing chemical sensors that can detect these metals, ...
Metabolically activated heterocyclic N-oxide compounds for killing and visualizing hypoxic cancer cells
(University of Missouri--Columbia, 2009)
Tirapazamine (TPZ) is currently undergoing a variety of phase I, II, and III clinical trials for the treatment of various human cancers. TPZ derives its medicinal activity by inducing DNA damage in poorly oxygenated tumor cells. Selective...
Merging technology development of trapped ion mobility spectrometry quadrupole time-of-flight mass spectrometry with biological investigation of Medicago truncatularoot exudates
(University of Missouri--Columbia, 2020)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] "New commercial ion mobility instrumentation has the potential to improve current analytical techniques, but developments need to be applicable to ...
Forage production and diversification for climate-smart tropical and temperate silvopastures
(University of Missouri--Columbia, 2019)
Climate change creates much uncertainty for the future of animal agriculture, particularly due to an increase in summer droughts that result in the loss of range productivity. Silvopasture, the intentional integration of ...
Effects of prescribed fire on forest soil properties in the Ozark Highlands
(University of Missouri--Columbia, 2020)
Prescribed fire is commonly applied to meet a variety of forest management objectives, including the restoration and maintenance of Oak (Quercus spp.) woodlands. In the Ozark Highlands, private landowners, conservation ...