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Go low or say No to aggressive systolic BP goals?
(Family Physicians Inquiries Network, 2016)
"Go low" or say "No" to aggressive systolic BP goals? The SPRINT trial demonstrated the benefits -- and risks -- of reaching a systolic target <120 mm Hg in non-diabetic patients at high risk for CV events. Here's who might benefit. Practice changer...
Deliver or wait with late preterm membrane rupture?
(Family Physicians Inquiries Network, 2016)
Deliver or wait with late preterm membrane rupture? While ACOG recommends delivery for all women with ruptured membranes after 34 weeks' gestation, a new study finds expectant management may be the way to go. Practice changer: In the absence...
Resistant hypertension? Time to consider this fourth-line drug
(Family Physicians Inquiries Network, 2016)
Resistant hypertension? Time to consider this fourth-line drug For most adults with resistant hypertension, spironolactone is superior to doxazosin and bisoprolol as an adjunct to triple therapy. Practice changer: When a triple regimen of an ACE...
Which nonhormonal treatments are effective for hot flashes?
(Family Physicians Inquiries Network, 2016)
Q: Which nonhormonal treatments are effective for hot flashes? Evidence-based answer: Selective serotonin reuptake inhibitors (SSRIs [fluoxetine, sertraline, paroxetine]) and the selective norepinephrine reuptake inhibitor ...
Kidney stones? It's time to rethink those meds
(Family Physicians Inquiries Network, 2016)
Kidney stones? It's time to rethink those meds. Despite being recommended for ureteral stone expulsion, tamsulosin or nifedipine are no more effective than placebo. Practice changer: Do not prescribe tamsulosin or nifedipine for stone expulsion...
Which SSRIs most effectively treat depression in adolescents?
(Family Physicians Inquiries Network, 2016)
Q: Which SSRIs most effectively treat depression in adolescents? Evidence-based answer: We don' t know which selective serotonin reuptake inhibitors (SSRIs) are the most effective and safe because no studies have compared ...
Which patients with metabolic syndrome benefit from metformin?
(Family Physicians Inquiries Network, 2016)
Q Which patients with metabolic syndrome benefit from metformin? Evidence-based answer: Patients at highest risk for progression to diabetes benefit from metformin. In patients with metabolic syndrome who are in the ...
Is lower BP worth it in higher-risk patients with diabetes or coronary disease?
(Family Physicians Inquiries Network, 2016)
Q: Is lower BP worth it in higher-risk patients with diabetes or coronary disease? Evidence-based answer: There is no simple answer; the risk/benefit picture is complicated. Controlling blood pressure to a target of 130/80 ...
Does breastfeeding affect the risk of childhood obesity?
(Family Physicians Inquiries Network, 2016)
Q: Does breastfeeding affect the risk of childhood obesity? Evidence-based answer: Yes. Even having breastfed during the first year of life is associated with a 15% lower risk of overweight or obesity over the next 2 to ...
Which treatments are safe and effective for chronic sinusitis?
(Family Physicians Inquiries Network, 2016)
Q: Which treatments are safe and effective for chronic sinusitis? Evidence-based answer: for adults with chronic rhinosinusitis (crs), intranasal steroid (ins) therapy is more likely than placebo to improve symptoms (50% ...
Does vitamin D without calcium reduce fracture risk?
(Family Physicians Inquiries Network, 2016)
Q: Does vitamin D without calcium reduce fracture risk? Evidence-based answer: No. Supplemental vitamin D without calcium -- in doses averaging as much as 800 IU per day -- doesn't reduce the risk of hip, vertebral, or nonvertebral fractures...
Consider melatonin for migraine prevention
(Family Physicians Inquiries Network, 2017)
An effective migraine prevention alternative with minimal adverse effects Melatonin is an accessible and affordable option for preventing migraine headaches in chronic sufferers.
Tamsulosin for patients with ureteral stones?
(Family Physicians Inquiries Network, 2018)
Tamsulosin for patients with ureteral stones? Yes, but only for some. Find out which of your patients can benefit. PRACTICE CHANGER: Prescribe tamsulosin for stone expulsion in patients with distal ureteral stones 5 to 10 mm in size....
Which anticoagulant is safest for frail elderly patients with nonvalvular A-fib?
(Family Physicians Inquiries Network, 2022-11)
Consider apixaban, which demonstrated a lower adverse event (AE) rate than warfarin regardless of frailty status, for anticoagulation treatment of older patients with nonvalvular atrial fibrillation (AF); by comparison, ...
Noncardiac inpatient has acute hypertension: Treat or not?
(Family Physicians Inquiries Network, 2022-09)
A retrospective study found more harm than benefit from treating elevated blood pressure in hospitalized noncardiac patients.
Can vitamin D prevent acute respiratory infections?
(Family Physicians Inquiries Network, 2019)
Can vitamin D prevent acute respiratory infections? A systematic review and meta-analysis says Yes, but the dosages used may not be what you'd expect. PRACTICE CHANGER: Reduce acute respiratory tract infections in those with significant vitamin D...
Do statins alter the risk or progression of dementia?
(Family Physicians Inquiries Network, 2018)
Q: Do statins alter the risk or progression of dementia? Evidence-based answer: No. Moderate-intensity statin therapy (with pravastatin or simvastatin) doesn't prevent progression to dementia in patients at increased risk. No prevention studies...
Debt types and burdens by family structures
(2020)
Purpose: The purpose of this study is to examine family structure differences in debt types and burdens of American families. Design/methodology/approach: Data are obtained from the 2016 Survey of Consumer Finances. Eight types of family structures...
Bariatric surgery plus medical therapy : effective Tx for T2DM?
(Family Physicians Inquiries Network, 2019)
Bariatric surgery + medical therapy: Effective Tx for T2DM? Short-term studies have indicated "Yes," but does a longterm randomized controlled trial give it a thumbs up? PRACTICE CHANGER: Consider bariatric surgery with medical therapy as a...
How effective is spironolactone for treating resistant hypertension?
(Family Physicians Inquiries Network, 2019)
Q: How effective is spironolactone for treating resistant hypertension? EVIDENCE-BASED ANSWER: VERY EFFECTIVE. Spironolactone reduces systolic blood pressure (SPB) by 11 to 17 mm Hg and diastolic blood pressure (DPB) by ...