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On-demand pill protocol protects against HIV
(Family Physicians Inquiries Network, 2016)
On-demand pill protocol protects against HIV: Finally, there's an effective prevention strategy -- other than condoms -- that can be used, as needed, by patients at high risk for HIV infection. Practice changer: Offer patients at high risk for human...
Yeast infection in pregnancy? Think twice about fluconazole
(Family Physicians Inquiries Network, 2016)
Yeast infection in pregnancy? Think twice about fluconazole. This study's findings regarding the risk of miscarriage may mean it's time to forego fluconazole in favor of topical azoles as first-line treatment. Practice changer: Avoid prescribing...
Which SSRIs most effectively treat depression in adolescents?
(Family Physicians Inquiries Network, 2016)
Q: Which SSRIs most effectively treat depression in adolescents? Evidence-based answer: We don' t know which selective serotonin reuptake inhibitors (SSRIs) are the most effective and safe because no studies have compared ...
Aneuploidy screening: Newer noninvasive test gains traction
(Family Physicians Inquiries Network, 2016)
Favorable results from the 2 studies reviewed here have prompted ACOG to recommend that cell-free DNA screening be discussed with all pregnant patients. Practice changer: Discuss cell-free DNA testing when offering fetal aneuploidy screening...
More isn't better with acute low back pain treatment
(Family Physicians Inquiries Network, 2016)
More isn't better with acute low back pain treatment Adding cyclobenzaprine or oxycodone/acetaminophen to naproxen for the treatment of acute low back pain does nothing more than increase adverse effects. Practice changer: Consider treating patients...
How do clinical prediction rules compare with joint fluid analysis in diagnosing gout?
(Family Physicians Inquiries Network, 2016)
prediction rules, the most accurate rules developed for research purposes, have a sensitivity of 92%, specificity of 89%, positive likelhood rati of 8.36, and negative likelihood ratio of 0.09 (strength of recommendation [SOR]: A, prospective cohort studies...
Is lower BP worth it in higher-risk patients with diabetes or coronary disease?
(Family Physicians Inquiries Network, 2016)
Q: Is lower BP worth it in higher-risk patients with diabetes or coronary disease? Evidence-based answer: There is no simple answer; the risk/benefit picture is complicated. Controlling blood pressure to a target of 130/80 ...
Which nonhormonal treatments are effective for hot flashes?
(Family Physicians Inquiries Network, 2016)
Q: Which nonhormonal treatments are effective for hot flashes? Evidence-based answer: Selective serotonin reuptake inhibitors (SSRIs [fluoxetine, sertraline, paroxetine]) and the selective norepinephrine reuptake inhibitor ...
Does vitamin D without calcium reduce fracture risk?
(Family Physicians Inquiries Network, 2016)
Q: Does vitamin D without calcium reduce fracture risk? Evidence-based answer: No. Supplemental vitamin D without calcium -- in doses averaging as much as 800 IU per day -- doesn't reduce the risk of hip, vertebral, or nonvertebral fractures...
What are the risks of long-term PPI use for GERD symptoms in patients > 65 years?
(Family Physicians Inquiries Network, 2019)
Q: What are the risks of long-term PPI for GERD symptoms in patients > 65 years? EVIDENCE-BASED ANSWER: THE USE OF PROTON PUMP INHIBITORS (PPIs) to control gastrointestinal esophageal reflux disease (GRED) is significantly associated with increased...
Do probiotics reduce C diff risk in hospitalized patients?
(Family Physicians Inquiries Network, 2019)
Do probiotics reduce C diff risk in hospitalized patients? A systematic review and meta-analysis says, "Yes," but that doesn't necessarily mean they will start appearing on hospital formularies. Practice changer: Start probiotics within 1 to 2 days...
Direct oral anticoagulants or warfarin for A fib?
(Family Physicians Inquiries Network, 2017)
A recent study evaluated the effectiveness of 3 direct oral anticoagulants and warfarin in patients with atrial fibrillation. So which agents came out on top? PRACTICE CHANGER: Use direct oral anticoagulants instead of warfarin in patients...
Do statins alter the risk or progression of dementia?
(Family Physicians Inquiries Network, 2018)
Q: Do statins alter the risk or progression of dementia? Evidence-based answer: No. Moderate-intensity statin therapy (with pravastatin or simvastatin) doesn't prevent progression to dementia in patients at increased risk. No prevention studies...
Can unintended pregnancies be reduced by dispensing a year's worth of hormonal contraception?
(Family Physicians Inquiries Network, 2019)
Q. Can unintended pregnancies be reduced by dispensing a year's worth of hormonal contraception? Evidence-based answer: probably, although studies that looked directly at this outcome are limited. A systematic review showed ...
Consider melatonin for migraine prevention
(Family Physicians Inquiries Network, 2017)
An effective migraine prevention alternative with minimal adverse effects Melatonin is an accessible and affordable option for preventing migraine headaches in chronic sufferers.
What's the best VTE treatment for patients with cancer?
(Family Physicians Inquiries Network, 2018)
Q: What's the best VTE treatment for patients with cancer? Evidence-based answer: No. Head-to-head studies directly compare all the main treatments for venous thromboembolism (VTE) in cancer patients. Long-term treatment (3-12 months) with low...
How effective is spironolactone for treating resistant hypertension?
(Family Physicians Inquiries Network, 2019)
Q: How effective is spironolactone for treating resistant hypertension? EVIDENCE-BASED ANSWER: VERY EFFECTIVE. Spironolactone reduces systolic blood pressure (SPB) by 11 to 17 mm Hg and diastolic blood pressure (DPB) by ...
The cost of a GMO-free market basket of food in the United States
(University of Missouri, College of Agriculture, Food and Natural Resources, 2016)
to the cost of a typical market basket of food consumed by American households, GMO-free food consumption would increase the average family food budget from $9,462 to $12,181 per year....
Exploring individual, family, and community factors predicting business success in Hispanic and Latino experiences
(Cambio Center, 2012)
This research examines what selected individual, family, and community factors best predict Hispanic/Latino male and female entrepreneurs? engagement in entrepreneurial activities and business success. In this study, individual factors...
Exploring behavior on Facebook during the 2016 presidential election
(University of Missouri--Columbia, 2018)
This research explores behaviors on Facebook during the 2016 presidential election. Rooted in selective exposure theory, the study builds on established quantitative research. Prior research has shown social media users are unfollowing, unfriending...