There is insufficient evidence to recommend for or against routine screening mammography beyond the age of 69 years. The best candidates to stop screening are elderly women who have significant comorbidities, poor functional ...

The primary motivation to screen asymptomatic women after a hysterectomy is to prevent morbidity and mortality from gynecologic cancer. However, primary vaginal cancer is rare, the vaginal Pap test is not particularly ...

Docusate sodium given 15 minutes before irrigation is most effective for facilitating cerumen removal during a single office visit. (Grade of recommendation: B, based on head-to-head trials that lacked irrigationonly arms.) ...

Cranberry juice (200 mL daily to 250 mL 3 times daily) or cranberry concentrate tablets (at least 1:30 parts concentrated juice twice daily) reduce recurrent, symptomatic urinary tract infection (UTI) in women by 12% to ...

Scant evidence exists for the best duration of steroid therapy for contact dermatitis due to plants (rhus). Review articles recommend 10 to 21 days of treatment with topical or oral corticosteroids for moderate to severe ...

Screening patients for asymptomatic microhematuria does not appear to improve outcomes, since screening does not identify a population with increased prevalence of urologic malignancy (strength of recommendation [SOR]: A, ...

Vitamin C 500 mg daily for 50 days reduced the risk of complex regional pain syndrome for patients with a wrist fracture. We think vitamin C 500 mg a day for 7 weeks is well worth recommending. Stength of recommendation: A: Based on 2 consistent...

Recommend high-dose vaginal probiotic capsules to prevent recurrent bacterial vaginosis. Stength of recommendation: B: Based on a single high-quality randomized controlled trial (RCT).

A recent study provides modest evidence for observational management over interventional treatment, sparing patients from invasive procedures.

Recommend aspirin 975 mg (3 adult tablets) as a viable first-line treatment for acute migraine. Consider prescribing metoclopramide 10 mg to be taken with aspirin to markedly decrease associated nausea and help achieve ...

[SOR]: A, based on multiple randomized controlled trials [RCTs]). Nonpharmacologic therapies, such as behavior therapy, school- based interventions, and family therapy, are not as effective as stimulants but may add modest benefit to the effects...

Short-term use of metformin (Glucophage) improves ovulation rates for women with polycystic ovary syndrome (PCOS) (strength of recommendation [SOR]: A, based on systematic reviews of randomized controlled trials [RCT]). ...

MRI is highly accurate in diagnosing injury to the anterior cruciate ligament (ACL) (strength of recommendation [SOR]: A, prospective blinded cohort studies) and posterior cruciate ligament (PCL) (SOR: B, limited number ...

In African Americans with hypertension, therapy is best initiated with the low-sodium Dietary Approaches to Stop Hypertension (DASH) diet and a thiazide-type diuretic (strength of recommendation [SOR]: A, based on randomized ...

The use of topical triple-antibiotic ointments significantly decreases infection rates in minor contaminated wounds compared with a petrolatum control. Plain petrolatum ointment is equivalent to triple-antibiotic ointments ...

It's unclear, as no studies have specifically evaluated therapies for uncomplicated urinary tract infections (UTIs) in breastfeeding women. However, trimethoprim/sulfamethoxazole (TMP/SMX), b-lactam antibiotics, nitrofurantoin, ...

. Frenotomy should be performed with anesthesia by an experienced clinician to minimize the risk of complications (SOR: C, a practice guideline.)...

Evidence from clinical trials supports the use of pneumococcal polysaccharide vaccine for prevention of pneumonia in nursing home patients (strength of recommendation: B, based on randomized, nonblinded clinical trials). ...

Although African American men, men with a first-degree relative with prostate cancer (CaP), and older men constitute higher-risk subgroups, no well-designed randomized controlled trials are available that show PSA testing ...