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Role of microRNAs in the legume - rhizobium nitrogen fixing symbiosis
(University of Missouri--Columbia, 2019)
between soybean, an important legume crop, and rhizobia. In the first example, our results suggest that gma-miR319i functions as a positive regulator of nodule number during the soybean - Bradyrhizobium symbiosis by targeting the TCP33 transcription factor...
Investigating the role of germline RNA helicase-1 in Caenorhabditis elegans
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The germline specific RNA helicase GLH-1, a constitutive P-granule component, and DCR-1, the riboendonuclease responsible for processing small RNAs in the miRNA pathway, have...
Microrna detection by surface plasmon resonance
(University of Missouri--Columbia, 2014)
outcomes. MicroRNAs are small non-coding nucleotides that have been shown to be up regulated or down regulated in cancer patients and miRNA-155 is one such microRNA whose molecular profile is up regulated in lung cancer patients. The focus of this work...
Microrna regulation of bursicon in drosophila melanogaster
(University of Missouri--Columbia, 2014)
by activating relish, a transcriptional factor in the immune deficiency (Imd) pathway. However, the regulatory mechanism of bursicon expression remains unknown. MicroRNAs (miRNAs) are small noncoding RNAs, acting as post-transcriptional repressors by base...
Sex differences in cardiac structure and function of Zucker diabetic fatty male and female rats
(University of Missouri--Columbia, 2016)
of microRNAs (miR-29 and miR-208) and genes they target by qRT-PCR. We hypothesized that sex differences exist in the expression of both miRNA families which may contribute to not only disease progression, but increased risk of myocardial damage in diabetic...
Altered microrna expression profiles in bovine fetuses with an assisted reproduction-induced congenital overgrowth syndrome
(University of Missouri--Columbia, 2018)
found between BWS and LOS. A previous study in our laboratory found global misregulation of transcripts in bovine fetuses with LOS. microRNAs (miRNAs) have been shown to play important roles in post-transcriptional regulation of gene expression...
Conservation and divergence of reproductive phasiRNAs in flowering plants
(University of Missouri--Columbia, 2021)
. Reproductive organs of monocots produce abundant phased, small interfering RNAs (phasiRNAs). The 21-nt reproductive phasiRNAs triggered by miR2118 are highly enriched in pre-meiotic anthers, and have not been described in eudicots. The 24-nt reproductive phasi...
Plasma miRNAs as novel biomarkers for breast cancer detection [abstract]
(2010)
MicroRNAs, a family of 19- to 25-nucleotide noncoding RNAs that primarily regulate genes at post-transcriptional level, are frequently dysregulated in cancer including breast cancer. Recent studies demonstrate that the ...
Which drugs should post-MI patients routinely receive?
(Family Physicians Inquiries Network, 2010)
the best evidence (SOR: B, a single RCT) a beta-blocker (SOR: A, meta-analysis) renin-angiotensin-aldosterone system blockers, whether or not the ejection fraction is diminished after myocardial infarction (MI) (SOR: A, meta-analysis for angiotensin...
Do re mi shhh!
(University of Missouri. Alumni Association, 1973)
"These students are using electric pianos with earphones. They can hear themselves play; the teacher can listen to students individually, talk with them without leaving his piano, and even play for them; the students can ...
Upper GI bleeding with myocardial infarction : evaluation of safety for endoscopy
(2012)
Upper gastrointestinal bleeding (UGIB) in the setting of acute myocardial infarction (MI) is a complex medical condition with substantial morbidity and mortality. The anemia due to the UGIB may exacerbate the MI or the anticoagulation for the MI may...
Comprehensive profiling of micro RNA in human papillomavirus-associated squamous cell carcinoma of the head and neck
(University of Missouri--Columbia, 2014)
How accurate is the use of ECGs in the diagnosis of myocardial infarct?
(Family Physicians Inquiries Network, 2006)
The electrocardiogram (ECG) is a fairly accurate test in the diagnosis of myocardial infarction (MI). However, given more sensitive technologies, such as cardiac biomarker testing, its primary role should be as an important adjunct in the evaluation...
Does moderate exercise prevent MI for patients with coronary heart disease?
(Family Physicians Inquiries Network, 2004)
Moderate exercise reduces mortality for patients with known coronary heart disease but does not significantly decrease the risk of recurrent nonfatal myocardial infarction (MI) (strength of recommendation [SOR]: A, based on systematic review...
The effects of drought stress and western corn rootworm feeding on maize root biology
(University of Missouri--Columbia, 2010)
of transposable element interference or post-transcriptional regulation by small RNAs, i.e. siRNAs or miRNAs. Three classes of miRNA were identified based on their response to WCR+wb, WCR-wb, and control treatments in the CRW3 germplasm; WCR-specific response...
Target concept learning from ambiguously labeled data
(University of Missouri--Columbia, 2017)
of representative or discriminative target concepts. The multiple instance hybrid estimator (MI-HE) maximizes the response of the hybrid detector under a generalized mean framework and estimates a set of discriminative target concepts. MI-HE adopts a linear mixture...
Differential effects of increasing physical activity and reducing energy intake on cardiometabolic and energetic parameters in obesity-prone juvenile rats
(University of Missouri--Columbia, 2015)
less than 0.05). Dark cycle spontaneous physical activity (SPA) was significantly increased in the Ex group in comparison to Sed and WM groups. Using the Matsuda index (MI), Ex significantly improved insulin sensitivity compared to the WM and Sed group...
Characterization [of] nucleic acids unwinding and exploring its application in miRNA detection in the nanopore
(University of Missouri--Columbia, 2012)
MicroRNAs (miRNAs) are a class of short (~14-27 nucleotides) noncoding RNAs that regulate gene expression at the post-transcriptional level. Aberrant expression of miRNAs has been found in all types of tumors. Reverse transcription real...
Downstream chitin signaling mediated by CERK1 in Arabidopsis
(University of Missouri--Columbia, 2012)
Recent work identified a LysM-domain membrane associated receptor-like kinase (CERK1) as the chitin receptor in Arabidopsis thaliana. In order to further study downstream chitin signaling, we screened an Arabidopsis ...
Beyond political differences : the influence of exposure to disagreements and the mediating role of emotional responses on selective exposure
(University of Missouri--Columbia, 2012)
This study examined the influence of exposure to online discussion boards and discussion participation in the online discussion boards on opinion-challenging news use. Based on cognitive dissonance theory and media choice ...