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Making medicine solving the problems of molybdium-99 production [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2007)
The United States currently receives more than 90% of its molybdium-99 from outside sources like Canada and the U.K. Moly-99, as it is called, is a key ingredient for many chemotherapy treatments and medical imaging techniques; it is however...
Computational Evaluation of LEU Conversion for Production of Tc-99m. [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2006)
The imaging radioisotope Technetium-99m (Tc-99m) is currently being used about 10,000 times daily in the United States. There are no facilities in the U.S. capable of producing Tc-99m, rather the parent nuclide Molybdenum-99 must be imported from...
Evaluation of [99mTC(CO)3]-labeled ERBB-2-targeting peptides for breast carcinoma imaging [abstract]
(2010)
The purpose of this study was to radiolabel a novel ErbB-2-avid peptide, discovered
from bacteriophage display, with [99mTc(H2 O)3 (CO)3 ]+ and evaluate the in vitro cellular targeting and in vivo tumor imaging properties of the peptide in a mouse...
Thermal mehcanical hydraulic experimental tools for molybdenum-99 production target analysis
(University of Missouri--Columbia, 2013)
done much for the progression of nuclear materials, associated technologies must first be tested and qualified before they will see any practical use. Technetium-99m (99mTc) is a diagnostic radiopharmaceutical that is currently used about 100,000 times...
Thermal-hydraulic optimization for high production of low-enriched uranium based molybdenum-99
(University of Missouri--Columbia, 2009)
. In an attempt to address the growing demand, as well as to motivate the current reactors to stop using high-enriched uranium, the University of Missouri Research Reactor (MURR) has begun to produce molybdenum-99 using low-enriched uranium. The fission of uranium...
Engineering review and calibration of devices to measure coolant flow through irradiation positions at MURR [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2006)
producers use High Enriched Uranium (HEU) to create the Mo-99. In an attempt to demonstrate a method that does not use weapons-grade uranium, the University of Missouri Research Reactor (MURR) is trying to produce Mo-99 isotopes by irradiating Low Enriched...
Target test tube assembly process and design for the development of molybdenum-99 [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2007)
Molybdenum-99 (Mo-99) is used to create Tc-99, a widely used nuclear medicine diagnostic imaging radioisotope. In an attempt to decrease the need for imported Mo-99, development of mechanical systems to efficiently prepare low enriched uranium (LEU...
Target test tube assembly process and design for the development of molybdenum-99 [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Molybdenum-99 (Mo-99) is used to create Tc-99m, a widely used nuclear medicine diagnostic imaging radioisotope. In an attempt to decrease the need for imported Mo-99, development of mechanical systems to efficiently prepare low enriched uranium (LEU...
New Tc-99m carbonyl complexes of SN bifunctional ligands [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Technetium-99m one of the most attractive radioisotopes for use in imaging applications. For a radiopharmaceutical to be useful and effective for use under in vivo conditions, it is imperative to have high kinetic stability for the Technetium compounds...
Using phosphinimines for a Tc-99 environmental contamination sensor [abstract]
(University of Missouri - Columbia Office of Undergraduate Research, 2006)
Evaluation of [99MTc]glucarate as a breast cancer imaging agent : bench to bedside [abstract]
(2010)
The use of [99mTc]glucarate has been reported as an infarct-avid agent with the potential for very early detection of myocardial infarction. [99mTc]glucarate has also been postulated as an agent for non-invasive detection of tumors. The aim...
The thermal-mechanical analysis of targets for the high volume production of molybdenum-99 using a low-enriched uranium metal foil
(University of Missouri--Columbia, 2012)
Molybdenum-99 diagnostic imaging is the most commonly practiced procedure in nuclear medicine today with the majority molybdenum-99 produced with proliferation sensitive HEU. International and domestic efforts to develop non-HEU production...
Technetium from two perspectives : sulfide remediation and schiff base chemistry
(University of Missouri--Columbia, 2015)
Two major areas of focus in radiochemistry are environmental and pharmaceutical. This work looks at technetium-99 (Tc-99) chemistry from both viewpoints. The Manhattan Project led to millions of gallons of radioactive waste. The waste is stored...
Design of an electrical system for swaging targets in the production of molybdenum-99 [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2007)
Molybdenum-99 is used all over the world to make technetium-99m for use in medical and research fields. The Molybdenum-99 is made by placing low enriched uranium foil in a reactor and allowing it to be irradiated. In order to irradiate the uranium...
Multifunctional phosphinimine ligand for 99m-Tc(VII) stabilization [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
The preparation of higher oxidation state, in vivo stable, 99mTc(VII) (and
Re(VII)) transition metal complexes bearing biologically active molecules has
recently received considerable attention because of their ...
99mTc-DPR-SSS-BBN for diagnosis of human cancers [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
-SSS-BBN(7-14)NH] was purified by reverse-phase high-performance liquid chromatography and characterized by electrospray-ionization mass spectrometry. Radiolabeling investigations of with fac-[99mTc(CO)3(H2O)3]+ (Isolink®) provided for the metallated...
Technetium and rhenium (I and V) complexes for radiopharmaceutical applications
(University of Missouri--Columbia, 2016)
Technetium and rhenium have radioactive isotopes that are clinically useful for diagnostic (Tc-99m) or therapeutic (Re-186/188) purposes. This makes them attractive candidates for incorporation into pharmaceuticals. One way to incorporate...
Parking map and information
(University of Missouri--Columbia, 2001)
Parking pamphlet containing several maps identifying general locations as well as designated parking areas in and around the University of Missouri--Columbia campus....
Missouri's Changing Face: A Glimpse of Tomorrow
(University of Missouri Extension, 2003)
This OSEDA presentation on the topic of demographics discusses and predicts Missouri demographics, including school enrollment, population estimates by county and regionalization....
In vitro/in vivo assessment of novel 99mTc-bombesin conjugates in human cancer tissue [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2007)
investigations of with fac-[99mTc(CO)3(H2O)3]+ (Isolink®) provided for metallated conjugates of the following general structure: [99mTc(CO)3-DPR-(X)-BBN(7-14)NH2]. These new conjugates demonstrated the ability to target specific human tumors in rodent models...