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The role of RECK in the pathogenesis of nonalcoholic steatohepatitis
(University of Missouri--Columbia, 2022)
Reversion-inducing cysteine-rich protein with Kazal motifs, or RECK, is a cell surface-anchored glycoprotein and a critical regulator of the extracellular matrix (ECM). It has been examined extensively as an anti-metastatic ...
Lifestyle treatment in the regression of NASH: insulin resistance, lipid synthesis, and methodological innovation
(University of Missouri--Columbia, 2022)
for two weeks. The mice fed a HFD exhibited greater absolute CER turnover in both whole liver tissue and isolated mitochondria. Furthermore, while total liver concentrations did not differ between diet groups, the HFD elicited greater mitochondrial CER...
The role of hepatic mitochondrial function and mitochondrial turnover in the development and progression of nonalcoholic fatty liver disease and lifestyle modifications to treat the disease
(University of Missouri--Columbia, 2021)
Nonalcoholic fatty liver disease (NAFLD) and its more advanced form steatohepatitis (NASH) is associated with obesity and is an independent risk factor for cardiovascular, liver-related, and all-cause mortality. Available ...