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Unraveling the role of the endogenous complex gut microbiota in the Pirc rat model of human colon cancer
(University of Missouri--Columbia, 2018)
The gut microbiota (GM) has recently been shown to modulate several systemic conditions in human and model systems, most importantly in intestinal disorders. It has also been demonstrated to have significant impacts on ...
Genetic and microbiota-mediated phenotype variability in the min mouse model of human colorectal cancer
(University of Missouri--Columbia, 2019)
, and reduced adenoma multiplicity and overall burden. Finally, we asked whether the background genetics of related inbred mouse substrains C57BL/6J (B6/J) and C57BL/6NHsd (B6/N) have differential modifier effects with respect to the Min phenotype. Using F1 mice...