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Genome-wide exploration of direct GBX2 target genes and their contributions to mouse development
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The cells that comprise the vertebrate nervous system require molecular cues to determine their cellular position, identity and their ability to make appropriate connections...
Assessing the effects of anticoagulant rodenticides on non-target fish species
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Invasive rat species have negatively affected island ecosystems contributing to the decline and extinction of many endemic species. The eradication of rodents on islands can...
Characterization of an in vitro neural stem cell niche with educational component : stem cells and society
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] We describe a novel neural stem cell (NSC) culture system, derived from embryonic stem (ES) cells, that maintains and expands a population of neural stem cells similar to those...
Assessment of the microbiome associated with endangered orchids
(University of Missouri--Columbia, 2018)
or the potential effects of climate change. We studied two species of endangered terrestrial orchids in Missouri and, using DNA collected from soil and high throughput sequencing, evaluated the bacterial microbiome associated with these two orchid species....
Approaches for unveiling the kinetic mechanisms of voltage gated ion channels in neurons
(University of Missouri--Columbia, 2019)
Ionic currents drive cellular function within all living cells to perform highly specific tasks. For excitable cells, such as muscle and neurons, voltage-gated ion channels have finely tuned kinetics that allow the ...
Impact of selective motor neuron death on hypoglossal motor neuron survival and tongue morphology in a novel model of dysphagia
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Amyotrophic lateral sclerosis (ALS) is a devastating disease characterized by the progressive loss of motor neurons and paralysis of the muscles they innervate. Hypoglossal...
Brassicales to Brassica : integrating phylogenomics and population genomics
(University of Missouri--Columbia, 2020)
The Brassicales are an economically important order of flowering plants. Many crop species such as kale, broccoli, cabbage, cauliflower, canola oil, capers, and papaya, as well as the model plant organism, Arabidopsis ...
Ecological genomics of divergence, admixture, and fitness in the smallmouth bass (Micropterus dolomieu)
(University of Missouri--Columbia, 2021)
their extensive native distribution. Much less is known about levels and distribution of diversity within the species. In 1940, Carl Hubbs and Reeve Bailey published descriptions of two distinct subspecies: the Northern Smallmouth Bass (M. d. dolomieu), inhabiting...
Genetic diversity and distribution of the ringed salamander (ambystoma annulatum) across multiple spatial scales
(University of Missouri--Columbia, 2018)
that correspond to watershed boundaries. Within each cluster, I found evidence for decreased gene flow in recent generations, possibly due to the extensive timber harvest and land conversion of the CIH post European settlement. Over smaller spatial scales, I found...
Phylogenomics of orchids and their mycorrhizal fungi : trees, diversity, and the pursuit of symbiosis
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Phylogenetic trees show us how organisms are related and provide frameworks for studying and testing evolutionary hypotheses. To better understand the evolution of orchids...
Elucidation of the genetic control of carbohydrate partitioning in Zea mays
(University of Missouri--Columbia, 2019)
Carbohydrate partitioning, the process of transporting carbohydrates from sites of synthesis in hotosynthetic tissue to developing sink tissues, is crucial for the growth, development, and yield in plants and crops. ...
Periconceptional, gestational, and lactational exposure to unconventional oil and gas chemical mixture alters energy expenditure in adult female mice
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Unconventional oil and gas (UOG) processes involves injection of pressurized water, chemicals, and suspended solids thousands of feet under the surface to release natural gas...
Dissecting the genetic basis of carbohydrate partitioning in maize and sugarcane
(University of Missouri--Columbia, 2022)
Carbohydrate partitioning, the process by which carbohydrates synthesized in the photosynthetic source tissues (mature leaves) are mobilized to non-photosynthetic (sink) tissues, such as roots, seeds, and developing organs ...
Mechanisms of the phototropic pathway
(University of Missouri--Columbia, 2018)
Plants are sessile organisms and therefore are limited in their ability to gather resources. Therefore, they have evolved several mechanisms that aid them in their quest to gather light, water and nutrients. One such ...
Uncovering the genetic basis of seed amino acid composition in arabidopsis using a multi-omics integrative approach
(University of Missouri--Columbia, 2021)
Seeds are a vital source of protein in the diet of humans and livestock. However, protein composition in the seed is low, comprising about 10 percent of the total composition in the seed. Additionally, protein quality in ...
Tales of an 'invisible' life stage : survival and physiology among terrestrial juvenile ambystomatid salamanders
(University of Missouri--Columbia, 2019)
of the many amphibian species for which stage-specific data are lacking. Next, I reared larvae of five species (A. annulatum, A. maculatum, A. opacum, A. talpoideum, and A. texanum) from populations along an ~200 km latitudinal gradient in Missouri, USA...
Effects of prescribed fire and timber harvest on terrestrial salamander abundance, behavior, and microhabitat use
(University of Missouri--Columbia, 2014)
surveys for three years and used a statistical modeling approach that accounted for the tendency of terrestrial salamanders to be belowground and unavailable for surveys. I found that terrestrial salamander density at our Missouri Ozark study site ranged...
Identification, characterization and use of novel thermogenetic tools in drosophilia melanogaster
(University of Missouri--Columbia, 2019)
Extrinsic control of neural activity is necessary to decipher the neural mechanisms underlying behavior. Molecular tools that employ light (optogenetics) or temperature (thermogenetics) are primarily used for extrinsic ...
Mating systems in Nicotiana longiflora and N. Plumbaginifolia : the effect of interspecific interactions
(University of Missouri--Columbia, 2008)
The research presented here was focused on the effects of interactions between Nicotiana longiflora and N. plumbaginifolia on their mating systems. First, I conducted a series of observations and pollination experiments ...
Interactions between neuroanatomy, cognition, and ecology in Anolis lizards
(University of Missouri--Columbia, 2021)
The interactions between an organism and its environment are mediated by cognition, the substrates of which are in the brain. Cognition is ubiquitous across vertebrates, yet we still know very little about the factors ...