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Extracellular vesicles : novel mediators of conceptus-maternal interactions in sheep
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Infertility and pregnancy loss are common problems affecting reproductive efficiency, health and development in livestock. Pregnancy loss occurs most ...
Uterine regulation of preimplantation embryo development in fertility-classified heifers
(University of Missouri--Columbia, 2018)
Infertility and subfertility represent pervasive problems in domestic animals and humans, and embryonic mortality is a major factor influencing reproductive efficiency. In cattle, the majority of embryonic loss occurs ...
Biology of uterine glands : impact on reproductive function
(University of Missouri--Columbia, 2018)
by utilizing mouse models lacking uterine glands and/or FOXA2 in conjunction with in-depth histomorphological, transcriptomic and proteomic analysis. Results of these studies established: (1) uterine glands substantially impact homeostasis of the uterine...
Biology of uterine glands : impact on reproductive function
(University of Missouri--Columbia, 2018)
by utilizing mouse models lacking uterine glands and/or FOXA2 in conjunction with in-depth histomorphological, transcriptomic and proteomic analysis. Results of these studies established: (1) uterine glands substantially impact homeostasis of the uterine...
Zinc ion fluxes on the pathway to mammalian sperm fertilization competency
(University of Missouri--Columbia, 2019)
For decades, the role of the divalent ion calcium was the focus of understanding mechanisms leading to sperm fertilization competency and management of semen storage. Little focus has been placed on other divalent ions, ...
Extracellular vesicles, lipids, and lipoproteins in early pregnant sheep
(University of Missouri--Columbia, 2021)
In sheep, pregnancy establishment encompasses conceptus elongation, implantation, and placentation. These events are regulated by factors present within the uterine luminal fluid (ULF) from the endometrial epithelium and ...
Using metabolic and biochemical characteristics of postmortem muscle to investigate the interconnectedness of beef color, flavor, and tenderness
(University of Missouri--Columbia, 2021)
Understanding relationships between beef palatability and quality components are crucial for continued production of high quality and consistent beef products. Myoglobin concentrations at 48 and 336 h resulted in moderate, ...
Comparative transcriptional profiling of the uterus according to stage of the estrous cycle and pregnancy status in gilts
(University of Missouri--Columbia, 2007)
In most mammals, female reproductive tracts undergo extensive tissue remodeling throughout the estrous cycle and during pregnancy that arise in response to an array of endocrine, paracrine, and autocrine signals. These ...
The effects of elevated temperature on preimplantation-stage porcine embryos
(University of Missouri--Columbia, 2006)
It was the objective of these experiments to more fully characterize the biochemical and developmental responses of in vitro-produced preimplantation stage porcine embryos to elevated temperatures. In vitro fertilized (IVF) ...
Differential gene and protein expression in pig nuclear transfer extraembryonic membranes and blastocyst stage embryos
(University of Missouri--Columbia, 2010)
Nuclear transfer (cloning) is the process of transferring a donor cell nucleus into an enucleated oocyte. The oocyte and donor cell are subsequently fused and activated to allow for nuclear reprogramming and continued ...
The role of the mammary gland during heat stress
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Disruptive effects of climate change, such as increasing environmental temperature, have direct impacts on economic viability and efficiency of food ...
The effects of the selective estrogen receptor modulators MPP and raloxifene in normal and cancerous human and murine uterine tissue
(University of Missouri--Columbia, 2007)
The goal of this research was to determine the in vitro and in vivo effects of the Selective Estrogen Receptor Modulators (SERMs), methyl-piperidino-pyrazole (MPP), raloxifene, ICI 182,780 and 17[beta]-estradiol on endometrial ...
Glutamine metabolism and interactions with mechanistic target of rapamycin complex 1 in porcine preimplantation embryos
(University of Missouri--Columbia, 2021)
The ability to culture embryos has created opportunities for animal agriculture, including the refined selection of superior genetics, and for the medical field, allowing couples experiencing infertility to have biological ...
Effects of aflatoxin on hepatic gene expression in a poultry model
(University of Missouri--Columbia, 2008)
To determine the effects of dietary aflatoxin on hepatic gene expression in chicks, seventy five day old-male broiler chicks were assigned to three dietary treatments (0, 1 and 2 mg/kg aflatoxin/kg of feed) from hatch to ...
Tissue inhibitor of metalloproteinase-1 contributes to reduced fecundity in a rat model of endometriosis
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Endometriosis affects millions of women worldwide; its symptoms are pain and reduced fecundity. An established rat model was used which endometriosis ...
Involvement of mitochondrial transcription factor A (TFAM) in porcine gametogenesis and preimplantation embryo development
(University of Missouri--Columbia, 2007)
Mitochondrial Transcription Factor A (TFAM) is responsible for maintenance and transcriptional control of mitochondrial DNA (mtDNA). TFAM knockout is embryolethal. We have studied the expression and distribution of TFAM ...
Evaluating pig performance, carcass merit and processed pork quality when chestnuts and acorns are fed to Duroc-influenced pig genetics during late finishing
(University of Missouri--Columbia, 2019)
The objective of this study was to determine effects of feeding chestnuts and acorns on growth performance, carcass quality and further processed products of Duroc/Duroc crossbred finishing barrows. Barrows (n = 30) were ...
Efforts to identify large offspring syndrome during pregnancy through ultrasonography and maternal blood transcriptome analyses
(University of Missouri--Columbia, 2021)
Large offspring syndrome (LOS) is a fetal overgrowth condition observed in some bovine offspring produced in vitro. The main phenotypes of LOS is large body size due to overgrowth during development which can result in ...
Temporal effects of fescue toxicosis and heat stress on rat physiology and hepatic gene expression
(University of Missouri--Columbia, 2007)
Fescue toxicosis results from intake of toxins in fescue containing an endophytic fungus, Neotyphodium coenophialum. Time-related changes in rats associated with intake of an endophyte-infected fescue diet (E+) were evaluated ...
Potential diagnostic methods and nutritional changes to combat bovine respiratory disease in receiving cattle
(University of Missouri--Columbia, 2017)
Bovine respiratory disease (BRD) accounts for up to 70 percent of health disruptions and $500 million in associated medical costs and production losses, thus receiving considerable attention from cattle health personnel ...